基质外的

Alternative etiologies for the development of this disorder include intrauterine insult (ischemic, metabolic, or viral such as CMV) during the 12th to 24th week of embryologic development. This results in damage to the germinal matrix and radial glial cells. Radial glial cells act as mechanical guides by which neurons are transported to the outer cortex during development.

另一种病因可能是由于第12-24周期间的宫内损伤（缺血、代谢异常、或病毒感染如CMV），其结果导致生发基质和放射状胶质细胞的损伤，在神经元移行至外皮层的过程中，放射状胶质细胞充当着机械性向导的作用。

Objective To investigate the relationship between quantitative change of fibronectin or Laminin and growth and differentiation of leukemic cells.

目的 探讨细胞外基质纤连蛋白、基膜连接蛋白与白血病细胞生长、分化之间的关系。

Results (1)ATP could inhibit the proliferation of U937 cells with inhibition rate over 43% after 48hour ATP treatment;(2)ATP treated U937 cells numbers increased obviously in G1 phase,and apoptosis peak appeared before G1 phase,apoptotic cell number was 3.4% for 24hour,and was 22.7% for 48hour of ATP treated U937 cells;(3) Nuclear chromatin condensed into sperical masses bound cytoplasma membrane formed apoptotic bodies which is shed from membrane surface into intercellular medium;(4) Apoptotic bodies were nigrosine staining negtive.

结果 (1)ATP对U937细胞的增殖有按摩明显的阻抑作用，加药48h后增殖的抑制率可达43%以上；(2)ATP处理的U937细胞周期发生改变，G1期细胞数按摩明显增多，ATP作用24h时G1期前出现亚二倍体峰——凋亡峰，凋亡细胞数为3.4%，作用48h时凋亡细胞数增多为22.7%；(3)ATP处理的U937细胞首先在核内染色质浓缩成半月形贴近核膜，逐渐向核膜外移动，进入胞浆内再移向质膜内外面，紧贴质膜外面再逐步脱离细胞体，进入细胞基质中，成为游离的凋亡小体。

Methods Cell culture,flow cytometry,HE staining,Nigrosine staining and electron microscopy were used. Results (1)ATP could inhibit the proliferation of U937 cells with inhibition rate over 43% after 48hour ATP treatment;(2)ATP treated U937 cells numbers increased obviously in G1 phase,and apoptosis peak appeared before G1 phase,apoptotic cell number was 3.4% for 24hour,and was 22.7% for 48hour of ATP treated U937 cells;(3) Nuclear chromatin condensed into sperical masses bound cytoplasma membrane formed apoptotic bodies which is shed from membrane surface into intercellular medium;(4) Apoptotic bodies were nigrosine staining negtive.

结果 (1)ATP对U937细胞的增殖有明显的阻抑作用，加药48h后增殖的抑制率可达43%以上；(2)ATP处理的U937细胞周期发生改变，G1期细胞数明显增多，ATP作用24h时G1期前出现亚二倍体峰——凋亡峰，凋亡细胞数为3.4%，作用48h时凋亡细胞数增多为22.7%；(3)ATP处理的U937细胞首先在核内染色质浓缩成半月形贴近核膜，逐渐向核膜外移动，进入胞浆内再移向质膜内外面，紧贴质膜外面再逐步脱离细胞体，进入细胞基质中，成为游离的凋亡小体。

It is mainly inhibited as glomerular sclerosis, renal interstitial fibrosis and intrarenal vascular sclerosis.

目前，肾保护的研究主要从防治肾小球硬化、肾间质纤维化和肾内血管硬化等方面进行，其中减少细胞外基质过度积聚是其核心环节。

Objective: To observe the change of Leydig cell and extra-cellular matrix of testis in mice during experimental orchiditis.

目的：研究小鼠睾丸间质细胞和睾丸内细胞外基质在实验性睾丸炎期间的变化。

The decreased function of Leydig cells and damage of ECM in testis during experimental orchiditis might be the factors associated with the poor fertile ability.

发生睾丸炎期间，睾丸间质细胞功能下降，睾丸内细胞外基质受损，这可能是导致生育力下降的原因之一。

Drug intervention groups received either daily inhalation of budesonide, ipratropine or heparin respectively, starting on the 8th day or TGF-β1 monoclonal antibody(TB21)0.5 mg twice (6th and 19th day) via the tail veinous injection.

其它各药物干预组于制作模型第8 d起分别雾化吸入布地奈德（布地奈德组，12只）、溴化异丙托品（溴化异丙托品组，12只）和肝素（肝素组，6只）溶液。4周后检测小支气管平滑肌及胶原厚度，用免疫组化法及原位杂交法观察各生长因子在支气管肺内的表达，用放免法检测血清和BALF中细胞外基质成分Ⅲ型前胶原、层粘连蛋白及透明质酸。

Mutations in COCH gene may impair the gap-junction between the spiral ligament fibrocytes, and obstruct the potassium recycling in cochleae, then, the endocochlear potential will be declined, hearing loss and vestibular dysfunction will be induced.

内耳尤其耳蜗间质组织中，这种稳定的细胞外基质结构框架对维持钾离子稳态及蜗内电位水平具有重要意义。

Cartilage cells which are the only adult hyaline cartilage cells synthesize and secrete high specifical cartilage matrix.

关节软骨是一种特殊的结缔组织，覆盖在关节的负重面上，由软骨细胞及细胞外基质所构成，软骨细胞是成人透明软骨的惟一细胞，它合成与分泌高特异性的软骨基质。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。