基质外的

Matrix metalloproteinases, which degrade extracellular matrix and basement membrane, plays an important role in many inflammatory diseases.

基质金属蛋白酶(matrix metalloproteinases，简称MMPs)是可以分解细胞外基质和基底膜的蛋白质水解酶，在许多疾病中扮演重要的角色。

It is also one of the main etiological factors of bronchopulmonary dysplasia. Present researches show that extracellular matrix metabolism disturbance participates in pathophysiological process of acute and chronic lung injury.

目前认为，细胞外基质代谢紊乱参与了急、慢性肺损伤的病理生理过程，作为降解ECM成份最重要的基质金属蛋白酶及其组织抑制因子在这个过程中可能发挥了重要的作用。

RESULTS: We detected immunohistochemical evidence of type II collagen within both the extracellular matrix-rich and matrix-poor areas in all 15 cases of clear cell chondrosarcoma.

结果：在15例透明细胞软骨肉瘤的细胞外基质富集区和基质贫乏区，都发现了II型胶原的免疫组化证据。

The matrix metalloproteinases are a group of zinc-dependent endopeptidase with homogenous structure and function; it can degrade various components of the extracellular matrix.

基质金属蛋白酶是结构和功能同源的一组锌离子依赖的内肽酶家族，能降解细胞外基质的多种成分。

The evident damage of chloroplast ultrastructure in S.polyrrihiza appeared at pH 2.5, but no severe plasmolysis and chloroplast swelling were seen.

紫萍在pH 3.5时膜系统的外渗率仍较低，基粒和基质类囊体结构无明显改变：pH 2.5时叶绿体结构才出现严重伤害，但未见明显的肿胀与质壁分离现象。

Expression of collagen-binding integrin receptors in the mammalian sclera and their regulation during the development of myopia.

巩膜细胞外基质及基质金属蛋白酶在近视发展中作用的研究进展。

It starts transmitting information by integrating with lagen and stromatin by irritating osteocytes and chondrocytes to form rapidly extracellular matrix so as to promote repair of bone and cartilage injury.

转化生长因子β通过刺激骨、软骨细胞合成胶原和基质蛋白，快速形成细胞外基质，达到其促进骨、软骨损伤修复的作用。

The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte. Ever since, people tried their best to find a way to reconstruct articular cartilage.

中文题名人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究副题名外文题名 Cartilage induction of human mesenchymal stem cells and experiment on compound porous materials as cells' scaffold in vitro 论文作者刘晓岚导师周江南学科专业外科学研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2003 论文页码总数68页关键词骨组织工程软骨细胞骨髓基质干细胞壳聚糖高分子外消旋聚乳酸馆藏号BSLW /2003 /R68 /10 造成人体关节软骨损伤的原因主要为创伤和关节炎，关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复，但这种修复由于缺乏相应的刺激机制，只能形成纤维软骨，而不能形成符合关节生理、力学要求的透明软骨；单纯软骨部分损伤软骨组织内无血管，软骨细胞迁移迟缓，无法使损伤区域软骨细胞再生，因此，关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

Vascular endothelial growth factor is the most critical growth factor for angiogenesis, and matrix metalloproteinase-9 (MMP-9) is associated with extracellular matrix degrading and bone resorbing.

血管内皮生长因子(Vascular endothelial growth factor，VEGF)在血管的新生中起重要调节作用，基质金属蛋白酶-9(matrix metalloproteinase-9，MMP-9)可降解细胞外基质，引起骨吸收。

Two days after bone marrow MSCs compounded to nano-CS/COL scaffold, bone marrow MSCs presented globular shape and were scattered; Four days later, bone marrow MSCs presented shuttle shape, extended and anchored on the surface of nano-CS/COL by pseudopods; Eight days later, bone marrow MSCs proliferated and fused each other, and they secreted a lot of extracellular matrix, then which covered most material particles.

骨髓基质干细胞复合到纳米壳聚糖-胶原纤维支架后2 d，细胞呈球形散在分布；4 d 后细胞呈梭形，延展爬行且有伪足与材料表面锚靠；8 d 时细胞增殖，相互间融合，并有大量的细胞外基质分泌，大部分材料颗粒被覆盖。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。