基质外的

Matrix metalloproteinase 9 (MMP9) is one of the representative substances that can degrade basement membrane and extracellular matrix.

基质金属蛋白酶9(matrix metalloproteinase 9，MMP9)是降解细胞基底膜，包括细胞外基质的代表性物质。

Objective To show the effect of human chorionic gonadotrophin on the expression of invasion associated genes in choriocarcinoma cells.

滋养层细胞来源的绒癌细胞对组织具有浸润能力，这一行为与其表达和分泌基质金属蛋白酶以降解细胞外基质有关[1] 。

In view of practical problem during Sulige gas field development, this paper complete follow study content. Study material balance theory of two district compound gas reservoir. Carry out stress sensitivity experiment on matrix rock and labor created fracture core from Sulige gas field with America Core Company high pressure high temperature flow experimental instrument to study stress sensitivity change rule of different permeability matrix rock and created fracture core at the condition of time and again switch on and off well and different drawdown pressure. Carry out depletion experiment on matrix rock of different permeability serial combination with different kinds of allocation, using double core clamper serial connected experimental apparatus, to study gas well production performance of bi-zonal compound low permeability reservoir during low pressure production stage. At the basis of experimental study, establish single well simulation model to analyze development index infection caused by stress sensibility and production performance infection rule caused by inner formation and outer formation of bi-zonal compound gas reservoir permeability variation while considering stress sensitivity.

针对苏里格低渗气田开发中存在的实际问题，完成以下研究内容；研究了两区复合气藏物质平衡原理；利用美国岩芯公司高温高压流动实验仪，对取自苏里格气田基质岩芯和人工造缝岩芯进行应力敏感实验，研究不同渗透率基质岩芯和造缝岩芯在多次开关井和不同生产压差条件下的应力敏感变化规律；采用双岩芯夹持器串联实验装置，对不同渗透率串联组合的基质岩芯进行各种配产条件下的衰竭实验，研究两区复合的低渗储层气井在低压生产阶段的生产动态特征；在实验研究的基础上，建立单井模拟模型分析储层应力敏感性和非均质性对开发指标的影响，研究考虑应力敏感时两区复合气藏储层中内区和外区渗透率变化对开发动态的影响规律。

Result indicated that:(1) Different ground substance has effection ,taixian is the best one for rooting.

试验结果表明：（1）不同基质对扦插苗瓶外生根率影响较大，且苔藓是其扦插生根的最优基质。

Research of extracellular matrix is an important subject in tissue engineering, and also a problem of succedaneum of ECM.

细胞外基质研究是组织工程学的重要部分，即是重要基础研究内容，又是研究细胞外基质的替代物课题。

It is well-known that for eucaryotic cells, DNA is located in the karyon and can not penetrate to the cytochylema and the tissue fluid because the cell membrane can act as barriers for DNA transportation. Therefore, the appearance of DNA in cell matrix and the serum can indicate that some diseases have taken place. A main reason for cancer occurrence is the mutation of DNA. It may cause the change of the sequence and expression of cancer suppressor genes.

真核细胞的DNA广泛的存在于细胞核内的染色体上，由于核膜的选择性通透作用，使DNA无法分散到其它细胞的亚器官，加之细胞膜的隔离效果，DNA更难扩散到细胞外基质中，因此细胞外基质中DNA含量的增加往往也会预示某些疾病的发生。

Results :①The MVs were formed by osteoblast of the secret type、dentinoblast and process;② There was a mature process of the MVs in the extracellular matrix.The appearance of the hydroxyapatite was a major mature feature;③ HAP formed initially in the MVs entered into collage matrix and eventually mineralized;④ The shifting sign of HAP from MVs to the surface of collage fibril was observed.

结果：①MVs是由分泌型成骨细胞、成牙本质细胞及其突起芽生进入胶原基质；②MVs在细胞外胶原基质中有一个逐渐成熟的过程，并以羟基磷灰石（hydroxyapatite，HAP）晶体的出现为其主要特征；③HAP在MVs内形成、增多，最终进入胶原基质并进一步沉积、钙化；④部分胶原原纤维表面沉积的HAP 晶体与MVs分泌的晶体有明显的移形迹象。

Result The flexibility of the scaffold material was powerful. The load-elongation curve of the mechanical testing was similar to that of ACL, the maximum load, the ultimate stress and the Young's modulus of the scaffold materials were 52.61 N, 14.96 MPa and 202.08 MPa respectively. Human ACL cells displayed the representative characteristercs of the ligamentous fibroblasts, and synthesized extracellular matrix, such as type Ⅰand Ⅲ collagen protein. The scaffold materials had no cytotoxicity. Human ACL cells adhered, grew and proliferated well both on the surface and in the holes of the scaffold materials.

结果］韧带支架材料的柔韧性强，拉力测试的负荷－拉伸曲线与韧带的拉伸曲线相似，其最大负荷、极限应力和弹性模量分别为52.61N、14.96MPa和202.08MPa；体外分离培养的人前交叉韧带细胞呈典型的成纤维细胞特征，能在体外分泌Ⅰ、Ⅲ型胶原等细胞外基质；支架材料无细胞毒性，人前交叉韧带细胞可在支架材料上黏附、生长并分泌细胞外基质。

Whereas osteoporosis is unassociated with bone pain, osteomalacia has been associated with isolated or generalized bone pain.39,40 The cause is thought to be hydration of the demineralized gelatin matrix beneath the periosteum; the hydrated matrix pushes outward on the periosteum, causing throbbing, aching pain.7 Osteomalacia can often be diagnosed by using moderate force to press the thumb on the sternum or anterior tibia, which can elicit bone pain.7,40 One study showed that 93% of persons 10 to 65 years of age who were admitted to a hospital emergency department with muscle aches and bone pain and who had a wide ariety of diagnoses, including fibromyalgia, chronic fatigue syndrome, and depression, were deficient in itamin D.41

然而，骨质疏松症与骨痛无关联，而软骨病则与局部性或全身性骨痛有关。其原因被认为是骨膜下已去矿质化的胶原基质上发生的水合反应，水合的胶原基质在骨膜上向外扩张，引起阵痛。软骨病可通过以拇指适度挤压胸骨和胫骨前方以引起骨痛感。一项研究显示10岁到65岁中有93%的人向医院急诊室承认有肌肉疼痛和骨痛症状，他们还有一些其他症状包括纤维肌痛、慢性疲劳综合征、抑郁等，该研究显示他们都缺乏维生素D。本人已认领该文第9、10两部分，48小时后若未提交译文，请其他战友自由认领。本人已认领该文11、12部分编译，48小时后若未提交译文，请其他战友自由认领。本人认领第十三部分，48小时内交稿请战友纠错！

Matrix metalloproteinases, a gene family of Zinc-containing endopeptidase, degrade extracellular matrix and play an essential role in the metastasis process.

基质金属蛋白酶是一类Zn~(2+)依赖的与细胞外基质降解有关的基质金属蛋白酶，在肿瘤的侵润和转移中起重要的作用。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。