基础

Japonicum was firstly PCR amplified from S. japonicum cercaria cDNA library. Its recombinant prokaryotic and eukaryotic expression plasmids were successfully constructed and its nucleotide sequence was determined. It was firstly expressed in E. coli with MW of about 17 ku.

中山大学基础医学院病原生物学教研室；中山大学基础医学院病原生物学教研室；中山大学基础医学院病原生物学教研室；中山大学基础医学院病原生物学教研室；中山大学基础医学院病原生物学教研室广东广州510189；广州医学院病原生物学教研室；广东广州510180；广东广州510189；广东广州510189；广东广州510189；广东广州510189

The thesis studies the difference between GWSs composition and traditional workflow applications, proposes the implement mechanism and technical architecture of GWSs composition and defines the reference model of GWSs composition platform, which provide holistic framework and top-level guidance for studying dynamic GWSs composition technology, designing GWSs composition platform, and implementing representative composite service applications.2、Theories and methods of composite process modeling and process analysis. This thesis proposes a meta-model of Geo-spatial Web services composition process defining from two aspects, i.e. process and resource. According to the process definition meta-model, we propose a new Geo-spatial Web services composition Process/Resource model based on extended WF-net, which effectively resolves the problems on uncertain activity option and dynamic variation of service in composite process model. A notion with regard to soundness of process model is proposed from three aspects, i.e. the structural correctness of process model, validity of data link and validity of resource. The notion of soundness definitely gives a dividing line on correctness of composite GWS process. This thesis analyzes sufficient and essential terms of soundness, and studies compositional property of WSCP/R-net models which provides an effective method to construct a soundness WSCP/R-net model. According to WSCP/R-net, the thesis proposes composition algebra and studies the properties of it. Based on the composition algebra, 6 kinds of composite process reduction rules are induced to optimize the process.3、Geo-spatial Web service QoS model and its application architecture. This thesis proposes an extendable GWS QoS model from three aspects, i.e. Geo-spatial Web Service itself, networking conditions and service consumer which can be used to distinguish GWSs with overlapping or identical functionality. We work over the QoS evaluation methods of composite GWS process which can be used to guide the execution, monitor and service selection of composition process. Aming at some disadvantages in traditional Web service discovery model for its lacking of QoS supporting, this thesis proposes a new service discovery model SDMQ supporting QoS constraints.4、Technologies of composite service executing. SSPL, a new composite service process language, is defined to overcome the disadvantages of existing composite services process languages which can not adapt to the dynamic variation of Geo-spatial Web Services. An algorithm is described to translate WSCP/R-net model into SSPL. The thesis studies the model of dynamic services selection with QoS global optimization, presenting an algorithm GODSS to resolve dynamic services selection with QoS global optimization in GWSs Composition.5、Design and implement experimental system and representative applications. According to the research findings presented above, we design and implement an experimental system and construct two representative applications to show that our achievements are effective and practical.

针对当前空间信息服务聚合研究中存在的若干不足，本文重点在基于工作流的空间信息服务聚合框架、空间信息服务聚合流程建模和分析技术、空间信息服务QoS模型及应用体系以及空间信息服务聚合流程执行等几个方面进行深入研究，主要工作和创新点包括：1、基于工作流的空间信息服务动态聚合框架：研究了空间信息服务动态聚合和传统工作流应用的不同，在此基础上提出了基于工作流技术的空间信息服务动态聚合实现机制、技术体系和参考模型，为研究空间信息服务聚合的关键技术、开发服务聚合支撑平台以及在此基础上构造特定的空间信息服务聚合应用提供了总体框架和顶层指导。2、空间信息服务聚合流程建模和分析技术：首先基于动态服务聚合流程建模的需求和空间信息服务动态变化的应用实际，从服务聚合的过程维和资源维出发定义了服务聚合流程定义元模型；与之相对应，对基本的WF-net进行扩展，提出服务聚合流程/资源网作为空间信息服务聚合流程的形式化描述模型，有效解决了现有的基于基本Petri网和工作流网的服务聚合建模方法所不能解决的不确定路径选择和服务的动态变化性问题；从流程结构正确性、数据依赖有效性和资源实现有效性三个方面提出了WSCP/R-net健壮性的概念，明确界定了聚合流程正确性的标准，并对WSCP/R-net模型的健壮性分析方法和WSCP/R-net模型的组合特性进行了研究；提出了空间信息服务聚合代数算子并对其性质进行了研究，在此基础上提出了6种聚合流程约简规则，从而可达到优化聚合流程、提高聚合流程执行效率的目的。3、空间信息服务QoS模型和应用体系：从服务本身、网络环境和服务消费者三个层次出发，提出了一个可扩展的空间信息服务QoS模型GSQM，实现了对空间信息服务的度量和评价，并对GSQM不同质量要素信息的客观、公正采集方法进行了研究；研究了空间信息服务聚合流程QoS评价方法，有效支持了空间信息服务聚合流程的执行、监控以及服务选择等操作；针对目前的服务发现模型仅支持服务功能性描述、不能有效满足空间信息服务应用需求的现状，提出了一种新的支持QoS约束的服务发现模型SDMQ，并对模型的实现框架进行了研究。4、空间信息服务聚合流程执行技术：针对现有的服务聚合流程描述语言不能有效满足空间信息服务动态聚合流程描述的特点，基于BPEL4WS提出了一种新的空间信息服务聚合流程描述语言SSPL；研究了满足健壮性要求的WSCP/R-net模型向SSPL的转换算法，在此基础上可以满足用户无显式编码来实现空间信息服务聚合应用的目的；研究了服务动态选择QoS全局优化模型，并在此基础上提出了一种解决服务动态选择QoS全局优化问题的实现算法GODSS.5、基于论文研究成果，设计实现了"空间信息服务聚合实验系统"，并构建了"矿产资源评价"和"城市消防应急响应"两个典型应用案例，对论文所述模型、方法的可行性和有效性进行了验证。

At first, we describe economical and technical characteristics of infrastructure construction, differentiatlle gross and narrow range of infrastructure, which establish theoretical base for social capital entrancing into.

第一部分首先阐述了基础设施的内涵，区分了广义和狭义的基础设施，并对基础设施的技术和经济属性进行了分析，从而为社会资本进入基础设施领域奠定了理论基础。

The design and calculation of raft foundation ,the topic of whether to remain the permannent building separation for settlement between mair buildings and podiums,the piling design,and calculation for base settlement are introduced.

依据上海地基基础设计规范(DGJ08—11—1999)和《高层建筑混凝土结构技术规程》(JGJ3—2002)，结合多年的工程经验，详细阐述了在上海地区进行高层建筑基础设计时结构方案的选择，筏形基础设计与计算，主楼与裙房间是否要设永久沉降缝，桩基础的设计，以及基础沉降计算等常见问题。

The mechanical behaviour of anchorage foundations is then further studied by comparing that of a caisson without anchors. Meanwhile, the distribution of moment on anchor is analyzed; and the influence of anchors' embedded depth on the bearing capacity is studied.

在此基础上，通过无根键沉井基础和有根键沉井基础的受力特性对比，分析了根式基础的受力特性，对根键上的弯矩分布型式进行了研究，并探讨了根键沿深度位置分布对根式基础承载力的影响。

So, in view of the peculiarities of the short-term dynamic model and the impulse response function, impulse response is stable and sensitive. In the short-term period, the central bank has a greater control of Ml through the conduction of the base currency and the result is better. It can also prove that the money multiplier of our country has long and firm relations with other elements except the base currency. Through the short-term dynamic equation, it successfully calculates the money multiplier beyond the sample and provides the basis for the central bank to prefigure the regular alteration of the money multiplier.

实证检验显示，中央银行运用货币政策工具时受外汇占款变量的制约影响太大，而再贷款成了调控基础货币投放的主要对冲手段，它的作用的发挥有赖于外汇占款的变动情况，存在明显的被动性。2、基础货币与M1和M2存在长期稳定关系，从长期来看基础货币对M2的冲击影响强于对M1的影响，而从短期来看基础货币对M1的影响要强于对M2的影响；M1和M2在基础货币冲击下具有冲击的放大传导机制和缓沖传导机制，脉冲响应具有稳定性和灵敏性，基于短期动态模型和脉冲响应函数所表现出的特征。

This article that focuses on the systematic and in-depth research in the current primal problem about abnormal burst pressure reservoir depress burst pressure has procured following main fruits:1 It forms the method which could obtain massive vertical static state mechanics parameters.2 In a foundation of acquisition of rock mechanics parameters,apply bent lamella that as mechanical model along with characteristic of actual geologic characteristics to analysis curvature for anticlinal strcture, get homologous tectonic stress value throug relation between the curvature and stress and different principal curvature in anticlinal structure,consequently set up laminational stress model for anticline reservoir. The block lamination for existed fracturing date has formed method of setting up mechanical model of lamination terrestrial stress by abtaining the block tectonic stress coefficients which are got by complex utilization test, laboratory test and fracturing date playback.3 Analysesing the main reason which lead to high burst pressure by considering the characteristic of reservoir geology,reservoir,and rock mechanics and reservoir damage,etc.Establishing burst pressure quantitative prediction model which provide gist for depressing construction risk and optimizing construction craft under the condition of open hole completion ,gun-perforated completion and damaged reservoir.4 Provding theoretical basis for interpreting acidification pretreatment which could depress busrt pressure by finding the relation between the influencing factors and rock machanics parameters and analysing the factors that have effect on rock mechanics parameters. Expounding the mechanism of reaction of mixed monomineral and acid from the angle of microcosmic element, evaluating quantitatively acid sensilility of different kinds of mineral effectively, and determing the first-order reaction dynamical equation of each mineral.5 Revealing rock mechanics property chage as a result of acid flooding in different condition by sandstone traumata experiment in different temperatures which combined with rock mechanics triaxial stress experiment.6 Associating damage mechanics with sandstone acidizing, established sandstone damage mechanics model in the foundation of the recognition on the rock mechanics parametric variation which is caused by acid-rock reaction in both macroscopic view and microscopic view ,also demonstrated those processes and quantitative estimated the acid busrt pressure to direct the site operation.

本文针对目前异常破裂压力储层降低破裂压力的主要问题展开较为系统和深入的研究，取得了以下主要成果：1形成了利用测井资料，结合室内岩芯测试结果，获取静动岩石力学参数的相关性特征，从而获得纵向上大量静态力学参数的方法。2在获取了岩石力学参数的此基础上，利用弯曲薄板作为力学模型，结合区块实际地质特征对背斜构造进行曲率分析，通过曲率与应力的关系，利用背斜构造不同部位的主曲率求得相应的构造应力值，从而建立起背斜储层的分层应力模型；对已有压裂资料的区块分层，形成了综合利用测试、室内实验、压裂资料反演获得该区块构造应力系数，建立起分层地应力的力学模型的方法。3综合考虑储层地质、油藏、岩石力学特性和储层伤害等因素，分析造成高破裂压力的主要原因，综合利用岩石力学、弹性力学等知识，建立了裸眼完井、射孔完井条件下以及储层受到伤害后的储层破裂压力定量预测模型，为降低施工风险和优化施工工艺提供了依据。4完成了物性、岩性影响岩石力学参数的因素分析，找出了各影响因素和岩石力学参数之间的关系，为从机理上解释酸化预处理降低破裂压力提供了理论基础；从微观元素的角度阐述了单矿物与酸反应的机理；并在此基础上，有效评价了各种矿物的酸敏感性，定量确定了岩石中各矿物的一级反应动力学方程。5完成了不同温度下的酸液类型、酸液浓度、注酸量等一系列砂岩损伤实验，结合岩石力学三轴应力实验，系统揭示了在不同条件下注酸而引起的岩石力学性质变化。6将损伤力学与砂岩酸化相结合，在宏观、微观两个方面认识酸岩反应引起岩石力学参数变化基础上，建立了砂岩损伤力学模型，并对其进行验证，在此基础上定量计算酸化后的破裂压力，有效指导现场施工

As a part of the Rootstalk foundation research ,the paper introduce contrast of the vertical load and pull capacity, horizontal push capacity between the rootstalk foundation and the common caisson by means of 3-D FEM software analysis. The analysis shows that the rootstalk foundation has great practical potential and its mechanical behavior are preliminarily discussed.

本文结合参与安徽省高速公路总公司根式基础课题组的工作，应用三维有限元软件对根式基础与普通沉井基础进行了竖向抗压抗拔承载力，水平抗推承载力数值模拟对比，说明根式基础在工程应用上的潜力，并对根式基础的受力机理进行了初步探讨。

On this basis, according to historical data, apply ANN and differential simulation method to get the quantitatively correlative relations between each production and its own influence factors, and introduce the new methods of prediction for dynamic indexes with gas-field development (The combinatorial prediction method based on fuzzy comprehensive evaluation, the method of ANN to select optimally combinatorial prediction models and the ANN prediction method based on genetic algorithm).(2) Base on mathematical programming, combine with quantitative economics and techno-economics, introduce economical indexes to establish production"s distribution optimal model, production"s constitution optimal model and measured production"s constitution optimal model, including multi-objective models and five-years models. Upon this, the optimal project for all gas field and each gas-collected factory can be got. Also, introduce the time value of capitals to improve on these models.(3) Base on the optimal solution theory and algorithm theory for the nonlinear programming problem, introduce the SUMT algorithm and genetic algorithm to study how to solve the models, and on the basis of normal genetic algorithm, make use of auto-adaptively modulating method to improve on normal genetic algorithm; Base on algorithm"s convergence theory and calculation"s complexity theory to analyze seriatim SUMT algorithm"s convergence and genetic algorithms convergence, and compare performance with each other.

在此基础上，利用神经网络方法和微分模拟方法根据历史数据得到各分项产量与其影响因素之间的定量关联关系，并引入气田开发动态指标新的预测方法(基于模糊综合评判的组合预测方法、神经网络优选组合预测模型预测方法以及基于遗传优化的神经网络预测方法)；(2)以数学规划为基础，结合数量经济学和技术经济学，引入经济指标建立产量分配优化模型、产量构成优化模型、措施产量构成优化模型、气田开发多目标规划模型以及五年规划模型，进而获得全气田及各采气厂的最优方案，并引入资金时间价值对五年规划模型进行改进；(3)以非线性规划问题的最优解及算法理论为基础，引入SUMT算法以及遗传算法对模型的求解进行研究，并在原有的遗传算法基础上，引入自适应调整方法对遗传算法进行改进；以算法的收敛性理论和计算复杂性理论为基础，逐一分析SUMT算法以及遗传算法的收敛性，并比较三种算法的优劣性。

Groups were feeded with routine dietary(Zn37.15mg/kgDM),among which,group A was used to as the control group andB,C,D groups were added 120mg/kg,240mg/kg,360mg/kg Zn-Met in routine dietary. Pretesting date was 10 days.

各组奶牛均饲喂含锌量37.15mg／kg的基础日粮，其中，A组=基础日粮；B组=基础日粮+120mg／kg蛋氨酸锌；C组=基础日粮+240mg／kg蛋氨酸锌；D组=基础日粮+360mg／kg蛋氨酸锌，预试期为10天。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。