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基底细胞上皮瘤

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Key words: basal cell carcinoma; basal cell epithelioma

关健词]基底细胞癌;基底细胞上皮瘤

METHODS: COX 2 and VEGF protein expressions were detected by immunohistochemical staining in 15 seborrheic keratosis, 15 Bowen s disease, 20 basal cell epithelioma, 20 squamous cell carcinoma and 5 normal skin tissues.

免疫组织化学法检测脂溢性角化病15例,皮肤原位癌15例,基底细胞上皮瘤20例,鳞癌20例及正常组织5例COX 2和VEGF的表达。

Objective To investigate the expression of ezrin in seborrheic keratosis, basal cell carcinoma, squamous cell carcinoma and its relation to clinical pathology parameters.

目的 探讨埃兹蛋白在脂溢性角化病、基底细胞上皮瘤、皮肤鳞状细胞癌中的表达及其与临床病理参数之间的相关性。

Results With the expression in normal salivary gland as a standard, low C-erbB-2 mRNA expression was seen in adenolymphoma, basal cell adenoma. However, various degrees of over-expression of C-erbB-2 oncogene mRNA were detected in pleomorphic adenoma, mucoepidermoid carcinoma,acinic cell carcinoma ,adenoid cystic carcinoma ,papillary cystic carcinoma,and myoethelial cell carcinoma.

结果 正常涎腺和涎腺肿瘤中发现不同程度C-erbB-2mRNA的表达,以正常涎腺组织的表达水平为基准,在腺淋巴瘤、基底细胞腺瘤呈现低表达、无表达或与正常涎腺组织表达水平相似,多形性腺瘤、粘液表皮样癌、腺泡细胞癌、腺样囊性癌、乳头状囊腺癌和肌上皮癌则呈现不同程度的过表达。

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