基因组学

To this end,we used the Transwell system to select two highly invasive subcell lines SNU5-P3 and PAMC82-P3 from minimally invasive parent cells,and compared gene expression in paired cell lines wit...h high and low invasive potentials.38 genes were commonly upregulated in the two highly invasive subcell lines.

通过全基因组芯片比较SNU5-P3和PAMC82-P3与其亲本细胞的基因表达谱，获得了38个在两张芯片共同上调表达的差异基因，其中16/38(42%)已报道是与侵袭转移功能相关的基因。LOXL2是一个在两张芯片共同上调表达的基因，通过生物信息学分析和细胞表达谱分析，表明LOXL2可能是胃癌侵袭转移密切相关的功能基因。

To better understand and utilize this kind of transposable element, both bioinformatics and molecular biology methods are employed to identify and characterize MITEs in wheat genome.

为了更好地理解和利用这类转座元件，本文综合利用生物信息学与分子生物学方法，对小麦基因组中MITE元件的分子特征进行了研究，并利用它开发出了一种新型的分子标记。

As a result, the scientist reversed their thinking method, adopted reverse vaccine technology, from the whole genome sequence, developed B group meningococci vaccine successfully in 1-2 years.

应用逆向思维，采用逆向疫苗学的方法从基因组全序列出发，在1－2年的时间里就成功研制了 B 群脑膜炎球菌疫苗。

Identification of protein-coding genes in microbial genomes is one of the most important tasks in bioinformatics.

基因识别是进行基因组分析的第一步，在生物信息学研究中占有重要的地位。

As transcriptional factors, Homeobox genes play an important role in individual development and regulatory mechanism of cell differentiation.

对致病菌禾谷镰刀菌全基因组序列中可能的Homeobox基因进行生物信息学分析。

This chapter describes a number of bioinformatics techniques useful for analyzing poxvirus genomes.

本章描述了对痘病毒基因组分析有用的许多生物信息学技术。

Some of the software discussed here have been developed by members of the Poxvirus Bioinformatics Resource Center (PBRC; funded by National Institutes of Health ) specifically for use with poxvirus genomes.

这里描述的软件中的一些已经被痘病毒生物信息学资源中心(PBRC；由国立卫生院资助)的专门使用痘病毒基因组的成员所开发。

All the recombined suicide plasmids were successfully obtained and sequenced, and 24 unique sequences were identified. Bioinformatics analysis showed that there were 51 ORFs in the 24 operons.

对插入的随机片段进行测序后进行生物信息学分析，共证实有24个不同的基因片段，在TIGR4全基因组里面，这24个基因片段所处的操纵元结构中，总共包括51个开放阅读框，其中多数为含有多个ORFs的操纵元结构。

Tobacco tomato spotted wilt disease was found in many provinces.This disease is widely distributed in Yunnan production tobacco area and it causes above 60% losses in some area. The tomato spotted wilt disease is one of the most potentially dangerous disease of tabacco in the world. This paper reviewed the distribution,symptomology, causal agents, pathogenic mechanism, the composition and function of virus genome and epidemiology and management of the tobacco tomato spotted wilt disease.

目前该病在中国许多省均有发生的报道，在云南烟区广泛分布，在局部地区可造成60%以上的严重损失，烟草番茄斑萎病被认为是世界上对烟草最具潜在危险病害之一，较为系统全面的综述了烟草番茄斑萎病的发生与分布，病害症状学，病原物，致病机制，病毒基因组结构和功能以及病害的流行及控制等方面的研究进展。

Foxh1, a Smad DNA-binding partner, mediates TGFβ-dependent gene expression during early development. Few Foxh1 targets are known. Here, we describe a genome-wide approach that we developed that couples systematic mapping of a functional Smad/Foxh1 enhancer to Site Search, a program used to search annotated genomes for composite response elements. Ranking of SFEs that are positionally conserved across species yielded a set of genes enriched in Foxh1 targets.

在最新的研究中，加拿大多伦多大学和英国阿伯丁大学的研究人员开发出一种新的生物信息学的方法，把Smad/Foxh1功能性增强子系列制图与定点查找结合起来，进行全基因组范围的Foxh1靶蛋白搜索，并将搜索结果按照其在生物间的保守性打分分级。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。