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During the two critical periods—gametogenesis and preimplantation development, there are genome-wide epigenetic reprogramming in gametes and embryos, which plays important roles in the erasion or creation of imprinting, gene silencing and tissue-specific gene expression.

其中关键时期是配子形成期和胚胎植入前期,最主要内容是全基因组DNA"CpG岛"甲基化和染色质组蛋白乙酰化的有规律变化,结果是配子遗传印记的消除与重建、植入前胚胎大范围基因的静默和组织特异性基因表达的确定。

In the unsterilized soil, the colonization of JMC1402P was affected by the physical and chemical factors of soil, and the aboriginal microbe would compete with it.The safety of releasing JMC1402P to the surrounding was tested, the design was as follows: mixing JMC1402P and R. huakuii JS5A16L, JMC1402P and Pseudomonas fluorescens Pf.X16L2 in filterable membrane, sterilized soil and unsterilized soil.

JMC1402P标记菌株释放环境的安全性研究表明,当JMC1402P与华癸中生根瘤菌JS5A16L、荧光假单胞菌Pf.X16L_2混合培养在微孔滤膜上、灭菌盆装土及田间三个环境中时,未检测到华癸中生根瘤菌JS5A16L和荧光假单胞菌Pf.X16L_2中有gfp基因编码的绿色荧光蛋白的存在,在X-GlucA作用下亦没有带有gusA基因的发光菌落。

Although several gametogenesis-specific genes were identified previously, more genes related to the ovarian development are expected to be involved due to the complexity of gametogenesis.

虽然已有一些调控卵子生长和卵泡发育的特异性基因被发现,但与卵巢发育和卵子生长相关的更多基因的功能有待于进一步研究,阐明其在这复杂过程中的具体分子机制。

This result showed that the nucleotide sequence of the coding region and accordingly amino acid sequences of Myf-5 gene of gayal and cow, chimpanzee, rhesus monkey, human, dog, house mouse, Chinese softshell, chicken and zebrafish were quite conservative.

大额牛与普通牛、黑猩猩、恒河猴、人、狗、家鼠、软体贝壳、鸡、斑马鱼的Myf-5基因编码区核苷酸序列同源性分别为99.0%、90.0%、90.5%、90.5%、87.2%、84.8%、72.9%、64.3%、51.8%,相应的氨基酸序列同源性分别为99.6%、94.9%、94.6%、94.9%、89.9%、88.7%、81.6%、70.4%、56.6%,这说明大额牛与其他9个物种在Myf-5基因的编码区核苷酸和相应氨基酸序列上具有较高的保守性。

Barrier is a kind of boundary elements, which blocks the spread of heterochromatin and insulates the neighboring active genes from repression effects.

障碍子就是边界元件的一种,它可以使活性基因的表达免受异染色质的的作用,防止基因沉默。

Objective Loss of heterozygosity of tumor suppressor gene is believed to play a key role in carcinogenesis of colorectal cancer.

目的抑癌基因的杂合缺失被认为是结直肠癌形成的通路之一,本实验拟通过对染色体10q23~24区的LOH分析,发现高频杂合缺失区域并筛查与结直肠癌相关的抑癌基因。

The expression pattern of gibel carp pou2 suggests that this gene should play an important role during early stages of embryogenesis. It might regulate the formation of neural plate and the fate of midbrain and hindbrain cells during early embryogenesis.

银鲫pou2基因的表达图式提示该基因在胚胎发育的早期具有重要作用,它可能参与调控神经板的形成和中后脑细胞的发育命运。

Combined with animal model of peradaptation to myocardium ischemia , the research observed the level of enzymatic dynamics of myocardium, SOD,MDA,ET and correlation peptide of calcitonin gene in peripheral blood and cardiac function, apoptic cell and expression of apoptosis regulatory gene, ultrastructure of myocardium with BIOPAC16, in situ end labeling and hybridism, optic microscope and electron microscope. The study of animal model of peradaptation to myocardium ischemia illustrated that the peradaptation and pretreatment with Wenxin capsule could be positively protective for the injury of ischemia reperfusion. The protection is mainly reflected by reduction of infarction area, correction of heart rhythm abnormality of ischemia reperfusion, melioration of the contraction and relaxation function of myocardium, recovery of the subcellular structure and themelioration of the abnormality of biochemical and bioactive substance in the myocardium.

并结合心肌缺血预适应动物模型,采用BIOPAC16导生理记录和分析处理系统处理心肌功能指标,采用原位末端标记及原位杂交技术标记凋亡细胞及凋亡相关调控基因的表达,采用光电镜技术观察心肌超微结构的变化,同时观察外周血心肌酶、超氧化物歧化酶、丙二醛、内皮素、降钙素基因相关肽等水平,结果表明心肌缺血预适应及温心胶囊预处理对心肌缺血再灌注损伤具有肯定的保护作用,其保护心脏作用主要表现在缩小心肌梗死范围、抗缺血再灌注心律失常、改善心肌收缩和舒张功能、减轻心肌超微结构损伤,调节心肌生化物质及生物活性物质的生成和释放。

According to the sequence of the hydrolase gene, we designed the primers to clone the unknown sequence by rapid amplication of cDNA ends.

根据筛选所获得的其中一个阳性克隆水解酶基因的序列,设计引物,通过cDNA末端快速扩增的方法扩增基因的未知序列。

Day 3 of fifth instar is an important stage for silk protein synthesis and preparation for metamorphism.

家蚕在吐丝、变态发育等方面具有独特的生物学过程,对这些家蚕特异的锌指蛋白基因的进一步功能研究,可能揭示出这些基因与家蚕特异生物学过程的联系。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

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