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isolates recovered from tuberculosis patients of rual morth Jiangsu province with variable-number tandem-repeatgenotyping, and analyze factors related to the dominant VNTR genotype.

目的运用可变数目串联重复分型方法研究农村结核病研究现场的结核分杆菌分离株的分子特征,分析与VNTR优势基因型相关的因素。

Thus, the theoretical interpretation of adaptation is changed from the genotype explanation to organism's phenotypic explanation.

这样,就将适应的理论解释从基因型解释转化为生物的表型解释。

The chromatin unfolding assay showed that ,like the wild-type transactivation domain, two variants that represent benign polymorphisms did not induce chromatin unfolding or only induced subtle change. Contrary to the behaviors of the wild type and two benign variants, four cancer-predisposing mutations in the transactivation domain superactivate the chromatin unfolding. The results suggest that the chromatin unfolding assay can aid in the characterization of deleterious mutations in the C-terminal transactivation domain of BRCA1 and may provide more reliable presymptomatic risk assessment.

对这些重组质粒的染色质伸展活性检测表明,野生型pwt和两种良性多态性突变体不具有染色质伸展活性或只有极微弱的染色质伸展活性,而其他4种乳腺癌易感突变体均具有过强的染色质伸展活性,提示利用染色质伸展技术可预测BRCA1转录激活区基因型与乳腺癌发生风险的表现型的关系。

Results The positive cases of TTV-DNA were twenty-one in one hundred and thirty five aged viral hepatitis patients and the positive ratio was 15.6%; The TTV genic model was chief Ⅰ model (76.2%), The TTV singleness infection cases were two (9.5%) yet the superposable infection ratio was 90.5%, the difference had prominence.

结果 135例老年病毒性肝炎患者中TTV-DNA阳性者21例,阳性率为15.6%;TTV基因型主要为Ⅰ型(76.2%),TTV单独感染仅2例(9.5%),重叠感染率达90.5%,两者差异具显著性(P〈0.01)。

Objective To study relationship between serum and red blood cell folate, serum vitamin B12 (VB12), total plasma homocysteine, thermolabile genotypes, and activity of methylene-tetrahydrofolate reductase.

目的 探讨叶酸、维生素B12(VB12)、血浆总同型半胱氨酸、5,10-亚甲基四氢叶酸还原酶活性及其热敏感性基因型间的相互关系。

Objective To observe the unique DNA profile and the relationship between DNA profile and phenotype of Trichophyton rubrum, and establish an effective molecular method to identify T. rubrum.

目的用PCR方法扩增红色毛癣菌和须癣毛癣菌临床分离株的DNA,观察PCR指纹的差异以及基因型与传统表型的关系,建立一种红色毛癣菌分子生物学鉴定方法。

Objective To observe the unique DNA profile and the relationship between DNA profile and pheno type of Trichophyton rubrum , and establish an effective molecular biologic method to identify T. Rubrum.

目的 用聚合酶链反应扩增红色毛癣菌和须癣毛癣菌临床分离株的DNA,观察PCR指纹的差异以及基因型与传统表型的关系,建立一种红色毛癣菌分子生物学鉴定方法。

The Hardy-Weinberg equilibrium for genotypic distribution was estimated by the goodness-of-fit test. The UNPHASED program was applied to perform the transmission disequilibrium test, the haplotype analysis and the pair-wise measure of linkage disequilibrium between these 2 SNPs.

利用拟合优度χ2检验分析基因型分布频率是否符合Hardy-Weinberg平衡定律,应用UNPHASED软件包进行2个SNPs的传递不平衡检验、单倍型分析和连锁不平衡程度的测量。

Results The vaccinal vestige, BCO immunization and familial traits were the risk factors of tuberculosis. Frequency of wildness, mutant heterozygote and homozygote of MBP-54 was difference in cases and controls.

MBP-54位点野生型、突变型杂合子、突变型纯合子3种基因型在病例组和对照组中的分布频率不同。

Canalisation is a measure of the ability of a population to produce the same phenotype regardless of variability of its environment or genotype.

渠道化是一个群体产生相同表型的能力程度,不论其环境或基因型的可变性。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

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There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

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