基因型

Ob j ect i ve To reveal the relationship between PON-1 Q/R polymorphism, serum PON-1 activity and T2DM complicated by CAD in Chinese Han ethnic group and to provide objective evidence in the prophylaxes and management of T2DM complicated by CAD.Methods The subjects of the study consist of four groups:(1) T2DM group (22 men and 14 women, mean age 56 ?8 years);(2) CAD group (35 men and 6 women, mean age 60 ? 13 years);(3) T2DM complicated by CAD group(14 men and 13 women, mean age 66 ?9 years);(4) normal-control group(21 men and 12 women, mean age 57 + 11 years).

目的与方法本研究应用聚合酶链式反应—限制性片段长度多态性方法鉴定天津地区汉族人单纯T2DM患者36例、单纯CAD患者41例、T2DM合并CAD患者27例和正常对照组33例的PON-1 Q／R基因多态性的基因型，并测定血清PON-1活性，探讨PON-1在T2DM并发CAD中的作用，为该病的防治提供客观依据。

To isolate and clone the tumor suppressor gene on chromosomal region 7q32 that corelated with the occurrence of human NPC,we detected the genotype of polymorphic microsatellite markers on 7q32 in 24 nasopharyngeal carcinoma biopsies and matched normal lymphocyte DNA.

为了分离和克隆定位于7q32染色体区域的与鼻咽癌发病有关的抑瘤基因，检测了鼻咽癌活检组织及配对外周血标本中7q32微卫星DNA多态性位点的基因型，发现在7q32区域存在30%左右的杂合性丢失。

Among family members of genotype-positive infants, 51% were found to carry disease-causing mutations.

在基因型阳性婴儿的家庭成员中，51%携带致病性基因突变。

In an area where HBV and aflatoxin were risk factors, a close association of HLA-A02 genotype with hepatocellular carcinoma was identified.

启东肝细胞癌中HLA-A02基因型的相对集中与特征性的p53基因249密码子错义突变的高频度没有关联。

The frequency of C allee and the genotype Trp64Arg was higher in obese girls.

肥胖女童中变异等位基因、Trp64Arg 变异基因型的出现频率明显高于正常体重者。

There was no significant difference in frequencies of genotypes or alleles between the two groups.

两组人群在基因型和等位基因频率上均无显著的统计学差异。

Results The distribution of genotypes and alleles was significantly different between the control group and patient group.

结果：对照组与病例组等位基因的构成及基因型分布具有统计学意义。

The results showed that at 80% similarity level among the 42 tested strains there were 5 genotypes indicated by UPGMA dendrogram of nifH PCR-RFLP.

结果表明，在80%相似水平上42株根瘤菌nifHPCR-RFLP基因图谱中有5个基因型聚类群。

The sequence analysis of the complete F genes from two samples confirmed that like the results of the gene sequence analysis from other genes, BJ1816 and BJ1887 belong to two different dusters.

结论F蛋白的序列分析进一步证明BJ1816和BJ1887分属于不同的基因型，其F蛋白的基因特征与其他国外文献中所报道的hMPV相似，是病毒的膜表面糖蛋白，提示其在病毒的感染与免疫中起到重要的作用。

Objective To investigate the allele and genotype frequences of CYP2D6*10 in Ningxia Hui population.

目的 了解宁夏回族人群CYP2D6*10等位基因及基因型分布频率，为临床使用CYP2D6底物药物提供依据。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。