基侧的

Results AQP1 is expressed at the apical and basolateral membrane of the microvascular endothelium; AQP3 was detected at basal cells of both the bronchiole epithelium and submucosal gland acinus; AQP4 is present in the basolateral membrane of columnar cells in bronchiole; while AQP5 is expressed in the apical membrane of type Ⅰ pneumocytes, and also at the apical of columnar cells of superficial epithelium and submucosal gland acinar cells.

结果本研究发现AQPs基因在羊肺中的表达分布与人相似，AQP1在肺内的毛细血管内皮细胞表达；AQP3在小支气管黏膜上皮的基底细胞的基侧膜表达，AQP4存在于小支气管黏膜上皮的柱状纤毛细胞的基侧膜；AQP5存在于Ⅰ型肺泡上皮细胞的顶质膜，存在于小支气管黏膜上皮柱状纤毛细胞，以及在气道黏膜下腺的腺细胞的顶质膜表达。

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

The side-chain liquid crystal polymacrylate was synthesized by free radical polymerization form the acrylate monomer which was generated from p-hydroxy benzoic acid, ethylene chlorohydrin and acrylic acid by etherification, esterification and chloration.

以对羟基苯甲酸、氯乙醇和丙烯酸为主要原料，经醚化、酯化和酰氯化反应合成了中间体和含液晶基元的丙烯酸酯单体，后者经自由基聚合合成了聚丙烯酸酯侧链液晶聚合物。

P28 紫色 Formation of a peptide bond 肽键形成–4侧链具有的反应–形成二硫键-其它反应 Tyr,His,Arg Review Isoelectric Point Titration滴定 of an amino acid 滴定 Gly幻灯片 18 His Lys Glu Reaction of amino acids Section 4 Protein isolation and purification 蛋白质分离及提纯 Working With Proteins Experimental techniques for protein analysis and characterization Purification steps A cell contains many types of proteins In the lab we want to isolate a single protein for experiments Purification steps We first grow cells or isolate tissues that contain the protein of interest We break open the cells to produce a crude extract Use centrifugation离心 to separate soluble from insoluble material We fractionate 分离 the protein mixture based on properties of such as size, charge affinity or solubility.

丹磺酰氯与氨基酸反应生成荧光性质强和稳定的磺胺衍生物，用于多肽链NH 用于多肽链 3末端氨基酸的标记烃基化反应(1) 2，4-二硝基氟苯2，4-dinitrofluorobenzene，二硝基氟苯(二硝基氟苯 DNFB也叫做试剂。DNFB在弱碱性溶液也叫做Sanger试剂试剂中与氨基酸发生取代反应，生成黄色化合物二硝基二硝基苯基氨基酸(dinitro phenyl amino acid， DNP氨基酸氨基酸)苯基氨基酸氨基酸(2)苯异硫氰酸酯(phenylisothiocyanate， PITC)在弱碱性条件下，与氨基酸反应在弱碱性条件下，生成苯乙内酰硫脲 PTH衍生物，(phenylthiohydantoin， PTH)衍生物，即PTH-氨基酸，此反应又称之Edman反应，该反应是蛋白质或多肽氨基酸序列测定常用的反应。

In this condition, the parallel transformer can exhibit nearly zero impedance to harmonic current and very high primary self-impedance to fundamental current and thus lead harmonic current in power systems to flow into the transformer branch. With a step-down transformer, the power semiconductor switches of the active power filter are always worked in relatively low voltage, which ensure the security and reliability of the active filtering device.

实时检测并联变压器一次侧的谐波电流，根据谐波补偿条件，得到谐波补偿电流的指令信号，通过电力电子变流器跟踪产生谐波补偿电流注入到二次侧补偿绕组中，使得并联变压器对谐波电流呈现近似为零的低阻抗，对基波电流呈现很大的一次侧自阻抗，从而输导系统中的谐波电流流入并联变压器支路。

Results In normal vessels, an entire layer of internal elastica lamina was observed, however, in growing collateral vessels, IEL was disrupted, neointima was evident.

该研究首次报导猪后肢侧支血管生长过程中细胞外基质的降解十分活跃，对侧支血管的生长具有重要的作用。

The dissertation mainly consists of two parts:1. The Reaction Chemistry of Alkynes under Palladium Catalysis Part 1 studies the reaction α,β-unsaturated carbonyl compounds with alkenylpalladium intermediate generated by nucleopalladation, and discovered 1 the Pd-catalyzed tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls,2 the four-component tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls, 3 the tandem intramolecular oxypalladation-conjugate additionreaction of alkynoic acids with α,β-enals. These new reactions provide notonly efficient highly stereoselective methods for the synthesis of γ,δ-unsaturated,polyunsaturated carbonyl compounds and γ-lactonic aldehydes, but also thebasic transformations for a number of C-C bond formation reactions which can be usedto design synthesis of many acyclic, cyclic or polycyclic compounds.

本论文的主要工作分为两个部分：一、钯催化下炔烃的反应化学在本小组前人工作的基础上，我们详细研究了炔烃亲核钯化产生的烯基钯中间体与α，β-不饱和羰基化合物的反应，发现两价钯催化下卤离子-炔烃-α，β-不饱和醛酮的串联加成反应、卤离子-炔烃-α，β-不饱和醛酮的西组分串联加成及炔酸分子内氧钯化-串联Michael型加成反应；由此发展了γ，δ-不饱和醛酮、多不饱和羰基化合物和带有醛酮基侧链的γ-丁内酯衍生物的高立体选择性合成方法，这一过量卤离子存在下的烯基钯对α，β-不饱和羰基化合物共轭加成反应的发现，为大量碳-碳键形成反应的实现提供了基础，使我们能够从这一基本反应出发，设计和开发多种分子内、分子间的碳碳成键反应，以好的立体、区域选择性组建开链、环状及多环类型的化合物。

The aim of this study was to develop a novel amphiphilic functional block poly(ε-caprolactone) bearing ketone groups MPEG-b-P(OPD-co-CL. 2-oxepane-1, 5-dione was copolymerized with ε-caprolatone in which methoxy poly (MPEG, Mn=5 000) and stannous octoate were used as initiator and catalyst, respectively. The syntheses were conducted by bulk and solution polymerization. 1H NMR results showed that peak position and splitting of the polymers synthesized through solution polymerization were consistent with theoretical data, demonstrating the products were designed block copolymers. While in the bulk polymerization, polymer peak position was changed due to their high reaction temperature, suggesting their structural variation.

将带有羰基官能团的4-羰基己内酯和ε-己内酯分别在甲氧基聚乙二醇(MPEG，Mn=5 000)为引发剂，异辛酸亚锡为催化剂溶液和本体体系中开环聚合，合成了两亲性侧基带有羰基官能团的聚己内酯嵌段共聚物MPEG-b-P(OPD-co-CL.1H NMR结果表明采用溶液聚合法合成的聚合物各峰的峰位置和分裂情况与理论一致，证明了产物是实验所设计的嵌段共聚物，而采用本体聚合法合成的聚合物由于温度的影响，聚合物各峰的峰位置发生了变化，说明其结构发生了变化；差示扫描量热法分析结果表明随着OPD单体含量的增加，聚合物的熔点，玻璃化转变温度和熔融焓增加；热失重测试结果表明OPD单体的引入增加了聚合物的热敏感性。

The characteristic of protargol impregnated specimens was: the single kinety and complex kineties entered the vestibular after they rotated 1.5 coils. the peniculus 3 composed of 3 rows of kineties, of which one near the peniculus 2 was stopped at the joint of peniculus 1 and 3 and the end of the outer row of peniculus 1 had extraversion behavior.

蛋白银制片特征为：单毛基索和复毛基索旋转1.5圈后进入前庭，第3咽膜(P3)起始段由3列毛基索组成，其靠近P2侧的一列毛基索在P1与P3的汇合处终止，P1最外一列的末端外倾。

Poly(aryl ether sulfone ether ketone ketone) with side carboxyl attached to the main chain was synthesized by Friedel-Crafts polycondensation of 4,4′-diphenyoxyl diphenyl sulfone with trimellitic anhydride chloride.

以4，4′-二苯氧基二苯砜，偏苯三酸酐酰氯为单体通过Friedel-Crafts亲电反应合成了主链芳环上带有羧基侧基的聚芳醚砜醚酮酮树脂。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。