基侧的

These two penultimate residues TyrHC2 (140)α and TyrHC2 (145)βseem to play a more important role in propagating structural changes between different part of the molecule, such as the molecular surface,α〓β〓 interface and the haem proximal side in bar-headed goose Hb.

这二个Tyr残基在传递Hb分子不同部位的构象变化方面起了重要作用。如从Hb分子的表面至α〓β〓亚基交界面又至血红素临近侧。

Two SP1-like elements and half of binding motifs of RAR are found in the 119 bp region from -nt. 325 to -nt. 207 upstream of the first ATG. An AP1/cAMP like reaction element is found in the 113 bp region from -nt. 206 to -nt. 94 upstream of the first ATG of the CK13 gene 5' flanking region. We didn't know the reaction element CTGAATCA between -nt.

仔细分析CK13基因5'旁侧-nt.325~-nt.207之间119bp片段中，发现有两个类似的SP1反应元件及一个与半个维甲酸受体结合的模块，而CK13基因5'旁侧-nt.206~-nt.94之间113bp片段中-nt.199~-nt.192间的碱基CTGAATCA类似AP1/cAMP的反应元件。

From the calculations, it can be found that the van der Waals interactions, the hydrophobic interactions, as well as the H-bonding interactions are crucial for the ligand binding. The 4-phenylamino group can produce strong van der Waals adn hydrophobic interactions with the nonpolar side chains of the residues deep in the binding cleft. The R^1 and R^2 substituents on the bicyclic chromophore can also produce strong van der Waals and hydrophobic interactions with the residues located at the exterior part of the binding pocket. Moreover, the two N atoms of the quinazoline can form H-bonds with EGFR, which will produce significant contribution to biological activities. The calculated nonbonded interactions between anilinoquinazolines and EGFR, as well as the information obtained from the predicted complexes, can interpret the structure-activities of the inhibitors well, which can afford us important information for structure-based drug design.

从模拟结果得到的抑制剂和靶酶之间的相互作用模式表明范德华相互作用、疏水相互作用以及氢键相互作用对抑制剂的活性都有重要的影响，抑制剂的苯胺部分位于活性口袋的底部，能够与受体残基的非极性侧链产生很强的范德华和疏水相互作用，抑制剂双环上的取代基团也能和活性口袋外部的部分残基形成一定的范德华和疏水性相互作用，而抑制剂喹唑啉环上的氮原子能和周围的残基形成较强的氢键相互作用，对抑制剂的活性有较大的影响，计算得到抑制剂和靶酶之间的非键相互作用能以及抑制剂和靶酶之间的相互作用信息能够很好地解释抑制剂活性和结构的关系，为全新抑制剂的设计提供了重要的结构信息。

In this paper, PPVs derivatives with alkoxyl as side-chain and PPVs derivatives containing oxadizole were synthesized; the monomers and polymers were characterized as well. It was studied systemically the influence of component and molecular structure of main-chain and side-chain or side-groups on polymer solubility, electroluminescent and photoluminescent properties, thermostability, and light-emission device performance.

合成了烷氧取代以及主链中含有噁二唑的PPV衍生物，详细研究了各种单体和相关聚合物的合成并对其结构与性能进行了表征，系统研究了聚合物主链、侧链或侧基的组成与结构特征对聚合物的可溶性、电致发光特性、光致发光特性、耐热性以及电致发光器件性能的影响。

Leaves crowded toward apex of stems or spaced along distal part of stems, sessile or petiolate; petiole to 8 cm, base amplexicaul; leaf blade usually sword-shaped to elliptic-lanceolate, veins truly parallel from base, lateral veins absent.

叶密集向茎先端，或在茎上部间隔的，无柄或具叶柄；叶柄给8厘米，基部抱茎；叶片通常剑形到椭圆形披针形，脉真地平行的自基部，侧脉无。

The third-order optical nonlinearities and lime responses were measured by a phase conjugate forward, 3-dimensional degenerate, four-wave mixing technique. Comparing polymer's third-order NLO coefficient, it shows that the χsuperscript (3 value increasecs with the introduction of the azobenzol side-chain.

通过简并四波混频飞秒激光系统对各个接枝聚合物的三阶非线性极化率系数进行了测定，考察了偶氮侧链的引入对聚合物主链三阶非线性的影响，并考察了侧链上不同取代基的电子效应对主链三阶非线性的影响。

The fact that the compound, 2-methyl-2-di- methylaminomethyl-5--n-pentylidenecyclo- pentanone hydrochloride (T60) possessed little anticancer activity indicated that the Mannich bases that could formed a methylene group were necessary for anticancer activity.

当环戊酮环上的Mannich碱侧链位置上引入取代基时，抗癌活性显著降低，如化合物2-甲基-2-二甲胺甲基-5--亚戊基环戊酮盐酸盐（T60）几乎无抗癌活性。这说明Mannich碱能形成亚甲基是这类化合物产生抗癌活性所必不可少的条件。

Methods On same oral therapy condition,the patients in control groupwere given commmon thoracocentesis on twice a week,the patients in experimental groupwere treated by thoracic tube intubation with veinal catheter.After drainage within3days,the pleural cavity of the paˉtients in group E were injected with the compound of sodium hyaluranate,sodium carboxymethylcellulose and butyltriˉamcinolone.The patients of two groups were examined by X-ray after6months.According to the database of normal crowd chest X-ray photograph,the area of patient's photograph was drawn.The value of average gray scale in the area was gathered by image analysis system and to be compared with the value of normal side,so the gray ratio was got after correction.

在口服给药条件一致的前提下，对照组患者沿用常规每周2次间断抽液的方法；实验组采用静脉留置针持续引流的方法，3日内将胸液引流尽后注入由透明质酸钠、羧甲基纤维及丁基去炎松组成的可吸收生物活性凝胶。6个月后行胸片检查，图像分析系统根据正常人群胸片同侧拟合区域采集平均灰度值并与健侧相比，经校正后得灰度比。

Taking the particularity of the connection scheme of novel converter transformer and its filter system into account, it's necessary to find out the relation between its commutated reactance and short-circuit impedances between windings and fundament frequency impedance of filter branch for impedance design of novel converter transformer and reactive power ...

考虑到新型换流变压器及其滤波系统的接线方案较为特殊，了解其换相电抗与绕组之间的短路阻抗及阀侧滤波支路的基频阻抗之间的关系，对新型换流变压器的阻抗设计和阀侧无功补偿度的优化配置是十分必要的。

WANG Wei-Ting, GUO Lian-Jun, QU Ling, WANG Fang, LU Qing, QIAN Jia-Qing(Department of Pharmacology, Tongji Medical College, Huazhong Universityof Science and Technology, Wuhan 430030, China)By using decapitating, intravenous injection of saturated MgCl2 and legation of bilateral carotid arteries with vagi, theeffects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethyl- amino) propane hydrochloride on survival time in mice were studied. With the model of cerebral ischemia for 20 min and reperfusion for 10 min, effects of DDPH on the superoxide dismutases activity and malondialdehyde content in brain tissue and pathological changes were studied.

采用断颅，iv饱和MgCl2溶液及结扎双侧颈总动脉和迷走神经等法造成小鼠脑缺血模型，观察1-(2，6-二甲基苯氧基)-2-（3，4-二甲氧基苯乙氨基）丙烷盐酸盐对小鼠脑缺血后存活时间的影响；采用小鼠脑缺血（20 min）再灌注(10 min)模型，观察DDPH对脑组织超氧化物歧化酶活性，丙二醛含量及组织病理损伤的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。