基侧的
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The cytotoxicity of these compounds were valuated by MTT and SRB methods using three cancer cell lines: HL-60, A-549, P-388. Cyclo-shikonin, and cyclo-alkannin have high cytotoxicity against HL-60.The chiral center of side chain has no effect on their activity. 2- 1-(Acetyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (105) has strong inhibition effect on P-388 cells. 2- 1-(isooctyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (108) and 2- 1-(2-furoyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (112) have high inhibition on A-549.Shikonin (1), alkannin (2), and their derivatives have the structural features of a planar chromophores and short side chain. We examined the ability to inhibit the telomerase.
抗肿瘤活性初步筛选测试采用小鼠白血病P-388肿瘤细胞和人肺癌A-549肿瘤细胞进行,结果表明侧链羟基的手性对抗肿瘤活性无明显影响;有数个化合物具有很好的体外抑制活性,特别是化合物2-(1-异辛酰氧基-4-甲基-3-戊烯基)-5,8-二羟基-1,4-萘醌(108)和2-[1-(2-呋喃甲酰氧基)-4-甲基-3-戊烯基]-5,8-二羟基-1,4-萘醌(112)体外显示对人肺癌A-549肿瘤细胞有强效;2-(1-乙酰氧基-4-甲基-3-戊烯基)-5,8-二羟基-1,4-萘醌(105)对小鼠白血病P-388肿瘤细胞有强效;环紫草素和环异紫草素对人白血病HL-60细胞有强烈抑制作用。
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E. 3-allyloxyisothiazole and N-allylisothiazolone, were synthesized with 3-mercaptopropionate as the starting material through ammonolysis, cyclization and allylation reactions.
以3-巯基丙酸甲酯为原料,经氨解、关环、烯丙基化合成了2种含有不饱和侧链的异噻唑类化合物,分别为3-烯丙氧基异噻唑和N-烯丙基异噻唑啉酮。
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A clip for fixing a cladding sheet to an underlying support structure includes a base (5), a pair of side walls (7) extending from the base and converging towards each other, and a pair of flanges (9) extending outwardly and downwardly from the side walls.
一种用于将覆盖板固定到下面的支持结构上的夹子,包括一基部(5)、一对从该基部伸出并相互靠拢的侧壁(7)、以及一对从所述侧壁向外和向下延伸的凸缘(9)。
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The poly with p-aminophenyl-ethynyl as a side-group was synthesized through Pd-catalyzed Sonogashira coupling reaction between 4-[(2,5-dibromophenyl)ethynyl] aniline and 1,4-diethynyl-2,5-bis benzene.
通过单体4-[(2,5-二溴苯)乙炔基]苯胺和1,4-二乙炔基-2,5-二戊氧基苯之间的Sonogashira偶合反应合成了带有p-氨基苯乙炔基共轭侧基的聚对苯撑乙炔。
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At the same time, the importance of donor atoms pertaining to the side chain in the complexation reaction of three lariat azacrown ethers with alkali metal ions has been analyzed through the Fukui function.
同时,利用福井函数,对侧臂在氮基臂式冠醚与碱金属配位过程中的重要性进行了分析,结果表明氮基臂式冠醚的侧臂上供电子原子对整个冠醚分子与金属配位过程中有着十分重要的作用。
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The induced supramolecular chirality was found to be dependent on the absolute configuration of lateral residues, that is, the polymers with-configurational oxazolinyl chromophores tended to form chiral aggregates with levorotatory handedness, while polymers obtained from the-monomer offered dextrogyrate one upon the addition of Cu salt. A model, in which side groups would arrange in a helix fashion, is employed for describing the unusual chirality.
由此提出了侧基在Zn/Cu协同配位作用下形成螺旋状排列的模型,即侧基螺旋模型。N-噁唑啉苯基马来酰亚胺与甲基丙烯酸甲酯共聚得到了耐热性能好(热分解温度大于296℃)的光学活性聚合物~(25D=-7.8°(来源:Af4BC论文网www.abclunwen.com)~-36.6°。
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RESULTS: After 3 days of operation, the BMP positive cells were found in the matrix of experimental group I.
将自体成骨样细胞即刻种植在胶原包埋的聚羟基乙酸基质材料上,然后将该复合体或单纯基质材料移植到兔颅骨的一侧全层骨缺损区,作为实验侧或实验侧。
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The floral primordium is initially circular, along with the edge of which slight concaves occur. The outmost whorl of tepal primordia arises as a result of apical meristem division and the floral primordium then is in the shape of triangle. Two further whorls of tepal primordia arise in spiral acropetal sequence and are alternately arranged. When the innermost whorl of tepal primordia is at the late developmental stage, the foremost stamen primordia arise almost simultaneously in spiral acropetal succession and all of the stamen primordia are ultimately arranged in a triangle-cone form. Late in stamen primordium development, carpel primordia arise as same as the young stamen primordia and grow laterally. Grooves are present on the adaxial side of each carpel and develop into ventral sutures gradually closing up.
观光木的花原基最初为近圆形,随着顶端分生组织的活动,花原基边缘处出现浅凹,形成第一轮花被片原基,此时,花原基呈三角形排列,后两轮花被片原基依次发生,与前一轮互生;在内轮花被片发生的后期,最初几枚雄蕊原基几乎同时出现,呈螺旋状向顶发生,最后排列成三角圆锥状;雄蕊原基发育后期,心皮原基开始发育,形状与发育初期的雄蕊原基相似,随后心皮原基进行侧向生长,在近轴面出现浅凹,进而发育为凹槽,形成腹缝线,最后腹缝线完全愈合。
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First, 4-(2, 3-epoxypropoxyl) benzaldehyde was obtained by reaction of 4-hydroxy benzaldehyde and epichlorohydrin. Then, the Wittig reaction was carried out to convert EBD to styryl glycidyl ether.
首先用对羟基苯甲醛和环氧氯丙烷反应制备4-(2, 3-环氧丙氧基)苯甲醛,然后通过Wittig反应将醛基转化为乙烯基得到含环氧基团的功能性单体苯乙烯基环氧丙基醚,最后用ATRP方法聚合单体SGE得到含环氧侧基的聚苯乙烯。
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Petiole 8-20 cm, glabrous; leaf blade 5-7-foliolate; leaflets sessile, abaxially green, oblanceolate, 10-25 × 5-12 cm, abaxially glabrous or with sparse whitish hairs, ferruginous tomentose at base and in axils of lateral veins, base cuneate, margin crenate-serrate with teeth crenulate-serrulate, apex acuminate to subcaudate; lateral veins in 18-25 pairs.
叶柄8-20厘米,无毛;叶片5-7具小叶;小叶无柄,背面绿色,倒披针形, 10-25 * 5-12 厘米,背面无毛或者有稀少带白色毛的,被锈色绒毛在基部和在侧脉腋处,基部楔形,边圆齿状锯齿具细圆齿到细锯齿的牙齿,18-25对的侧脉。
- 推荐网络例句
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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.
随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。
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But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.
不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。
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Closes the eye, the deep breathing, all no longer are the dreams as if......
关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。