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Objective To investigate the expression of pituitary tumor transforming gene and clinical significance in pituitary marcroadenomas.

目的 探讨垂体瘤转化基因在垂体大腺瘤中的表达及意义。

In the ovary, the GnRHR positive cell reside in secondary follicle, mature follicle, corpus luteum, corpus albicans and atretic follicle.

在垂体内,GnRHR阳性细胞位于腺垂体,占细胞总数的31.5%,在神经垂体未发现。

Pituitary apoplexy is characterized by headache, visual loss, meningism, ophthalmoplegia, vomiting, hormonal dysfunction, and altered mental status caused by sudden hemorrhage or infarction of the gland.

垂体卒中是由于垂体腺瘤的突然出现或梗死从而引起头痛、视力丧失、假性脑膜炎、眼肌麻痹、呕吐、激素性功能障碍以及精神状态异常。

In the pituitary, the pattern of ghrelin mRNA expression during oestrous cycle markedly decreased in the estrus and metestrus. In the ovary, ghrelin mRNA exhibited with the highest level in the diestrus and the lowest in the proestrus, which was different from those in the hypothalamus and pituitary.

下丘脑ghrelin mRNA的表达在发情前期水平最高(p 0.05),发情期最低;在垂体,发情前期和间情期mRNA表达水平明显高于发情期和发情后期(p 0.01);而卵巢中Ghrelin mRNA表达模式不同于下丘脑和垂体,在发情前期水平最低,然后逐渐升高,在间情期表达水平最高(p 0.01)。

A monolayer culture system of pituitary cells was used to study the release of LH and FSH and their responses to a GnRH agonist,LRH-A3,in vitro by pituitary cells of prepubertal gilts at the ages of 30,60,90,120,and 150 days.

利用垂体细胞单层培养模型研究了30,60,90,120和150日龄北京黑猪母猪垂体细胞LH和FSH的释放及其对LRH-A3反应能力。

Adenomas within the sphenoidal sinus can be removed in 7 cases by cutting the sphenoidal plate and the tubercutum sella e and the anterior wall of sellsa floor.

显微切除鞍上肿瘤时应解剖出垂体柄和受挤压的垂体组织并加以保护,以免术中损伤。

In maximum width. Reportedly, in cadavers without pituitary adenomas the mean distance between the tuberculum sellae and the dorsum sellae was 10mm (7-14mm), the transverse diameter of the sellar floor was 14mm (9-18mm) in width. The measurements are less than ours.

我们测量的鞍底前后径和横径均较非垂体腺瘤患者尸体解剖测量值大,可能因为垂体瘤压迫使蝶鞍扩大所致。

And 15 cases of gliomas,5 of acoustic neuromas,3 of craniopharyngiomas,2 of chordomas and 1 of trigeminal neuroma showed type Ⅲ curves.

结果 :91 %(20/22)的脑膜瘤SI -T曲线为速升或快升型,其中血管瘤型均为Ⅰ型。垂体瘤75 %(9/12)表现为早期快速强化,尤以侵袭性垂体瘤为著。

Results: Compared with the C group, the contents of CORT in blood and ACTH in pituitary gland are increased at the different time points. Compared with the C group ,the contents of CR11 in Hypothalamus are enhanced in S and SAI groups on list but those are reduced in S and SM groups on 16st and 21st. Compared with the S group ,the contents of CORT in blood and ACH in pituitary gland are increased in SM group on 11 at. Compared with the SM groups, the contents of CORT in blood are reduced in TKXLD groups on 11st, l6st and 21st. Compared with the SAT group respectively, the contents of CRH in Hypothalamus are decreased in TKXLD group on list and those in TKXLD group are increased on 16st and 21st.

结果:实验第11、16和21天悬吊组和悬吊加辐射组大鼠血清CORT和垂体ACTH含量高于正常组;悬吊组和悬吊加辐射组大鼠下丘脑CRH含量在实验第11天高于正常组,在实验第16天和21天低于正常组;实验第11天悬吊加辐射组大鼠血清中CORT的含量高于悬吊组;实验第11、16和21天,中药组大鼠血清CORT含量低于悬吊加辐射组,垂体ACTH含量低于悬吊加辐射组;中药组大鼠下丘脑CRH含量在实验第11天低于悬吊加辐射组,在实验第16天和21天高于悬吊加辐射组。

In the coronary section of rat hypophysis, pars distalis, pars intermedia and pars nervosa were discernable under the light microscope.

在光镜下观察,大鼠垂体冠状切面上,可显示垂体3部分的结构关系,远侧部,中间部及神经部清晰可辨。

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