垂体的

Based on the understanding of physiological pathway for broodiness, three genes related to broodiness including PRL, PRL receptor, and pituitary-specific transcription factor (POU1F1)-encoding genes were selected as candidates to screen the genomic variation by means of PCR-SSCP protocol and analyze the association with chicken broodiness and other target traits.

禽类血浆PRL水平上升与就巢行为的起始和维持具有密切的相关性，本研究采用候选基因的策略，通过分析就巢行为发生的生理机制，选择与就巢性状密切关联的PRL、PRL受体和PRL转录调控因子——垂体特异转录因子(pituitary-specific transcription factor，POUlF1)基因，采用PCR-SSCP分析检测基因变异，并分析基因变异与就巢性和其它目标性状的相关性。

The experimental result shows:1 acupuncture and moxibustion on DU4 and RN4 can lighten inflammationreact , suppress the inflammation course, DU4 has the best result.2 IL-2 is the important factor of participating the immune respondence.Acupuncture and moxibustion can increase IL-2 content in the blood , thusstrengthen the immune function of the organism .3 acupuncture end moxibustion can raise β-EP content of lower thalamus ,hypophysis , lymph gland. it proves that acupuncture and moxibustion can stimulateand accelerate compound、store 、process 、shifting utility of β-EP content; andstrengthen the immune regulating function of the organism, acupuncture function isstrong rapidly, moxibustion function is slow and gentle, the regulating action powerof moxibustion has close relations with choice of the point . The possible reason isthat y whether acupuncture and moxibustion bring into play their regulating actionthrough different way of neural body fluid.4 The DU4、RN4、FEI point influence rule apply on change of β-EP content ofabove-mentioned organism.

实验结果显示：1 针灸命门和关元穴能减轻炎症反应，抑制炎症过程，命门穴效果最好。2IL-2 是参与免疫应答的重要因子，而针灸能增加血中 IL-2 含量，从而增强机体的免疫功能。3 针刺和艾灸可以升高下丘脑、垂体、淋巴结β-内啡肽含量，说明针灸可以刺激并加速β-内啡肽含量合成、储存加工和转移利用；增强机体的免疫调节功能，针刺作用迅速强烈，艾灸作用缓慢温和，艾灸的调节作用强弱还与穴位的选择有密切关系。

Methods ①In situ hybridization was applied to observe the changes ofhypothalamic CRHmRNA positive cells after PX and melatonin supplementation;②Immunohistochemistry was used to observe the changes of CRH positive cellsin hypothalamus and CRH staining in median eminence of neurohypophysis after PXand melatonin supplementation;③ELISA was applied to detect the changes of CRHconcentration in serum after PX and melatonin supplementation.

①运用CRHmRNA 原位杂交的方法来观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRHmRNA 阳性细胞的变化；②应用免疫组织化学染色的方法观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRH 阳性细胞和神经垂体正中隆起CRH 阳性染色的变化；③运用ELISA 法检测松果体摘除及补充褪黑素后血清CRH 浓度的变化。

Objective To study the morphological and functional effect of pinealectomy on CRH neurons in paraventricular nucleus of rat hypothalamus as well as thefunction of melatonin supplementation, enrich the research of the effect of pinealbody and melatonin on hypothalamic-pituitary-adrenal axis,provide theoreticalevidence of the effect of pineal body and melatonin on immune function andimmune-associated disease such as tumor and autoimmune disease.

目的： 研究松果体及其褪黑素对大鼠下丘脑室旁核CRH 神经元形态和功能的影响以及补充褪黑素的作用，丰富松果体及褪黑素对下丘脑——垂体——肾上腺轴影响的形态及功能方面的研究，为进一步揭示松果体及褪黑素对免疫功能以及免疫相关性疾病如肿瘤、自身免疫性疾病等的影响机制提供理论依据。

The results showed: 1 All GH deficient children presenting with polyuria and polydipsia had severe ADH deficiency; 2 In 11 GH deficient children without polyuria and polydipsia, 7 were found endogenous ADH insufficient; 3 The children with sho...

结果表明：(1)GH缺乏、伴多饮多尿症状的生长落后儿童均为ADH严重缺乏；(2)GH缺乏、无多次多尿症状的生长落后儿童11例中7例为潜在性ADH缺乏；(3)GH正常、伴多饮多尿症状的生长落后儿童都为ADH部分缺乏；(4)GH正常、无多饮多尿症状的生长落后儿童的下丘脑-垂体后叶功能基本正常。

HISI treatment prolong the survival time of mice in toxic condition induced by sodium nitrite and duration of electrocardiograph in trachea closed mice .HISI could obviously improve the ischemic electrocardiogram T-wave induced by Pituitrin.ST segment drifts on electrocardiogram in acute myocardial ischemia rats induced by Isoprotereno were obviously opposed by administration of HISI. The myocardial infarction areas, releasement of lactic dehydrogenase 、 creatine phosphokinase significantly increased in myocardial ischemia dogs, HISI treatment prevented these effects .

实验结果表明：苦碟子氯化钠注射液能显著延长小鼠常压缺氧环境及亚硝酸中毒情况下的存活时间，延长小鼠气管夹闭后心电消失时间；可显著改善垂体后叶素诱发的大鼠急性心肌缺血心电图T波异常；明显对抗异丙肾上腺素诱导的急性心肌缺血大鼠心电图ST段的偏移；显著改善冠脉结扎所致急性心肌缺血犬的心外膜心电图缩小其梗死心肌面积，降低心肌耗氧量，减少心肌坏死导致的心肌酶如乳酸脱氢酶、肌酸磷酸激酶的漏出。

AOPA, by "multiple relevant convergence reaction", adjusts and affects systematically the endocrinal function of bone metabolism,improves the levels of estrogen and CT/PTH, reverses the declining tendency of pituitary-thyroid axis function and improves thyroid function so as to weaken osteocyte in the bony absorption, enhance osteoblast in osteogenesis and increase bone density.

AOAP可以通过&多位点相关集合效应&综合调控影响骨代谢的内分泌功能，提高雌激素、降钙素/甲状旁腺素水平，扭转垂体-甲状腺轴功能减退的趋势，改善甲状腺的功能，使破骨细胞的骨吸收减弱，成骨细胞的骨形成增强，增加骨密度。

When MR imaging shows thickening and enhancement of the pituitary stalk and associated leptomeningeal disease as in this case, sarcoidosis is a very strong possibility, along with meningitis, particularly fungal.

结节病为一种不明原因的炎性病变，可以影像多个系统，包括中枢神经系统，女性多见，大于10：1，黑人比白人更多见，15%病人累及中枢神经系统，5%有神经症状，脑神经功能障碍和尿崩症是最常见的神经系统结节病的临床表现，MR改变包括脑膜增厚及强化，孤立性肿块或多发性小，散在的脑膜或实质病变，此例病例中MR图像出现增厚强化的垂体蒂伴有软脑膜病变，强烈提示结节病，伴随脑膜炎尤其是真菌性，通常T2表现为低信号，虽然这些也能够在霉菌病/淋巴瘤/脑膜瘤中看到。

There was no difference of FSHR expression in subcutaneous and omental adipose tissue from premenopausal, perimenopausal and postmenopausal men and women.

我们的研究首次阐述了脂肪组织上FSHR的表达和功能，第一次提出FSH直接调控脂肪分化、代谢的观点，FSH-FSHR信号调控开创了绝经期肥胖症研究的崭新方向，开拓了垂体糖蛋白受体新的研究领域。

Moreover, we established the model of apoptosis induced by corticosterone and explored the effect of gangliosides, which is a active component in pilous antler, on this apoptotic cell model. The effects of gangliosides on neurotransmitter release, neuronal filopodia formation, calcium signal cascade and 5-HTl A receptor-ligand competitive binding were also studied. 2. Theory study: The viewpoint on brain and kidney in traditional Chinese medicine and that in Western medicine were comparatively studied. The essence of the relationship between kidney and brain in traditional Chinese medicine Subsequently, in combination with the analysis on the results in the empirical study, we discussed the essence of the relationship between kidney and brain in traditional Chinese medicine from the viewpoint about the feedback mechanism of hippocampus-hypothalamic-pituitary-adrenal.

体外实验采用糖皮质激素建立神经细胞凋亡模型，研究鹿茸有效成分的干预作用，并从神经递质释放、神经细胞丝状伪足生成、神经细胞钙信号途径、5-HT_(1A)受体配体竞争结合等方面进行机制探讨。2、理论研究：比较中西医学对肾和脑的传统认识以及现代研究，分析中医学中肾和脑的现代科学内涵，结合实验研究结果，从现代生物学海马—下丘脑—垂体—肾上腺轴负反馈机制的角度对中医肾脑相关理论的实质进行探讨。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！