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Objective To investigate MRI manifestations of the posterior lobe and stalk of the hypophysis in central diabetes insipidus.

目的 通过垂体MRI观察中枢性尿崩症患者垂体后叶及垂体柄的改变。

The pituitary gland consisted of neurohypophysis and adenohypophysis. The adenohypophysis was divided into anterior lobe, intermediate lobe and posterior lobe.

黄颡鱼的脑垂体由垂体神经部和垂体腺部组成,垂体腺部又由前叶、间叶和后叶三部分构成。

The pituitary gland consists of neurohypophysis and adenohypophysis. Two types of pituicytes and three types of neurosecretory fibers (A1, A2 and B) have been recognized in neurohypophysis. The neurosecretory terminals contain different diameters and shape of secretory granules.

脑垂体由神经垂体和腺垂体2部分组成神经垂体组织中存在2种类型的脑垂体细胞,并可以区分A1型、A2型和B型3种类型的神经分泌纤维,其终端轴突中具有不同直径和形态的分泌颗粒;B型纤维轴突中含有许多透明小囊泡。

From the results of amino acids sequence comparison and analysis of functionally important sites of growth hormone,pituitary growth hormone of macaque from Cercopithecidae and snub-nosed golden monkey from Colobidae show little difference.

垂体生长激素氨基酸序列的比较和垂体生长激素重要功能位点分析的结果显示:猴科的猕猴与疣猴科的川金丝猴垂体生长激素基因差异非常小。

Results The bulging of the upper border of the pituitary gland and the shifting position of the pituitary stalk observed in the intensified MRI are the pathognomonic signs for the diagnosis of micropituitary adenoma. THe operation was stopped due to hemorrhage in one case.

结果 MRI 显示的垂体上缘隆起,垂体柄移位和T2加权上示高信号,这是诊断垂体微腺瘤独有的影像特征。11例中施肿瘤近全切除术10例,因出血终止手术1例。

Orexin A(100 and 1000 nM) stimulated the release of GnRH from hypothalamic explants harvested from prepuberal swine.However,only 1000 nM orexin B could stimulated the release of GnRH from the hypothalamic explants harvested from prepuberal swine.

五、Orexin对性成熟青年母猪下丘脑组织-垂体-卵巢轴作用的体外研究为探讨orexin在生殖调节中直接作用的靶位点,我们在体外培养了猪下丘脑脑片、垂体和卵巢细胞,研究了orexin A和orexin B在体外对下丘脑、腺垂体和卵巢GnRH、LH和E2释放的影响。

Patients with pituitary adenoma (84 PRL-secreting pituitary adenomas, 30 GH-secreting pituitary adenomas and 36 nonfunctioning pituitary adenomas) were treated by adnomectomy. The dynamic studies of serum PRL, GH, Cortisol, ACTH and thyroidal functions (T3, T4, TSH) were performed before and after microsurgery.

为了解垂体瘤手术对垂体激素分泌的影响,动态观察了150例垂体瘤患者在显微外科手术前后血清泌乳素、生长激素、甲状腺功能〔T3、T4、促甲状腺素〕、血皮质醇和促肾上腺皮质激素的变化。

Methods Samples from 78 patients with pituitary adenomas, including 37 invasive and 41 noninvasive, and 5 normal pituitary tissue specimens from autopsied patients were examined. The expressions of OPN mRNA and OPN were examined by real-time fluorescence quantitative PCR and immunohistochemical SP method, respectively.

分别对78例垂体腺瘤手术标本(其中侵袭性37例,非侵袭性41例)和5例来源于尸检的正常垂体组织进行检测,采用实时荧光PCR技术检测组织中OPN mRNA表达,免疫组织化学SP法检测OPN蛋白表达,结合临床资料分析OPN mRNA及其蛋白的表达与垂体腺瘤侵袭性的关系。

Methods samples from 78 patients with pituitary adenomas, including 37 invasive and 41 noninvasive, and 5 normal pituitary tissue specimens from autopsied patients were examined. the expressions of opn mrna and opn were examined by real-time fluorescence quantitative pcr and immunohistochemical sp method, respectively. the relation of opn and opn mrna expressions to invasiveness of pituitary adenomas was analyzed.

分别对78例垂体腺瘤手术标本(其中侵袭性37例,非侵袭性41例)和5例来源于尸检的正常垂体组织进行检测,采用实时荧光pcr技术检测组织中opn mrna表达,免疫组织化学sp法检测opn蛋白表达,结合临床资料分析opn mrna及其蛋白的表达与垂体腺瘤侵袭性的关系。

In conclusion, the pregnant result of group C was better than group B, D, E.2. The positive substance of TNF-αin group B was significantly increased than group A in the hypothalamus nuclei, neurohypophsis, pars intermedia, ovary follicle, corpus luteum, however, the expression of TNF-αwas obviously decreased in adenohypophysis.

B组TNF-α阳性产物的表达在下丘脑核团、神经垂体、垂体中间部、卵泡、黄体中均较A组显著增高,在垂体前叶较A组显著降低,在卵巢基质以及子宫中的表达与A组无显著差异。

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