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POU1F1 is the first certified pituitary transcription factor, it plays a role in control ofgrowth process and metabolism, it has far-ranging biological functions in improvinggrowth, reducing fat aggradation and so on.

POU1F1(pituitary transcription factor 1)是被鉴定的第一个垂体转录因子,它对哺乳动物的生长发育、新陈代谢起重要的调节作用,具有提高生长速度,降低脂肪沉积等广泛的生物学功能。

Prolactin,Growth Hormone, and Thyroid-stimulating Hormone-β, secreting by chicken anterior pituitary, are essential hormones affecting chicken laying ability, growth rate, and immunity via regulating chicken broodiness, development, and immune response.

催乳素(Prolactin,PRL)、生长激素(Growth Hormone,GH)、促甲状腺素β(Thyroid-stimulating Hormone-β,TSHβ)是家禽垂体前叶分泌的具有重要生理功能的激素,这些激素通过调控家禽就巢性的发生与维持、生长发育、免疫应答等过程来影响家禽的产蛋性能、生长性能以及免疫力。

College of Animal Science and Technology, China Agricultural University, Beijing 100094, ChinaProlactin,Growth Hormone, and Thyroid-stimulating Hormone-β, secreting by chicken anterior pituitary, are essential hormones affecting chicken laying ability, growth rate, and immunity via regulating chicken broodiness, development, and immune response.

催乳素(Prolactin,PRL)、生长激素(Growth Hormone,GH)、促甲状腺素β(Thyroid-stimulating Hormone-β,TSHβ)是家禽垂体前叶分泌的具有重要生理功能的激素,这些激素通过调控家禽就巢性的发生与维持、生长发育、免疫应答等过程来影响家禽的产蛋性能、生长性能以及免疫力。

During evolution, networks of gene groups are constructing of genomic stability, genetic co-adaptation and self-organization of genomes. Cytogenesis of endocrine cells within pituitary is in respond to hormones stimulation, and involved in induced expression of a serial transcription factors.

腺垂体干细胞分化成5种不同的内分泌细胞系,受上丘脑和性腺、胰岛细胞等激素的调控,涉及系列转录因子的诱导表达,成为细胞系发生研究的模型。

Investigation of the insulin-like growth factor system in breast muscle during development in Langshan and Arbor Acres chickensWe analyzed the effects of nutrient availability on the breast muscle insulin-like growth factor system.

本研究揭示了在生长轴、甲状腺轴和肾上腺轴中某些基因在特定时期在转录水平上的表达是相关的,并且发现下丘脑、垂体和肝脏中某些基因在品种间的表达差异是受营养因素调控影响的。2。

ResultsComparing with gonadectomy Shenyangxu model group, Wenyangyishen Capsules can improve upset excitability of male rat of gonadectomy penis Home News for Overseas Service Department , shorten erection incubation period; The rat increasing gonadectomy male sex attaches weight modulus of sexual organ; Can urge the hypophysis , adrenal gland weight modulus to increase by, weight adjusting the thymus gland , spleen; Elevate rat serum testosterone、Cortisol contents obviously; Be caused by messenger Cortisol the various Shenyangxu model small rat symptom gets laxation disappear even.

结果 与去势肾阳虚模型组比较,温阳益肾胶囊能提高去势雄性大鼠阴茎对外部刺激的兴奋性,缩短勃起潜伏期;增加去势雄性大鼠附性器官的重量系数;能促使垂体、肾上腺重量系数增加,调节胸腺、脾脏的重量;明显升高大鼠血清睾酮、皮质醇含量;使氢化可的松所致阳虚小鼠各项症状得到缓解甚至消失。结论温阳益肾胶囊具有益肾壮阳的功效。

It is believed that the dysfunctions of monoamine nerve in central nervous system and HPA axis are responsible for depression.

目前认为,中枢单胺神经和下丘脑-垂体-肾上腺轴功能异常可能是抑郁症发病的主要生物学原因,以此理论支持的抗抑郁药物虽有较好的疗效,但仍然对近30%的抑郁症患者无效。

The expression and axonal transport of pituitary adenylate ecelase-activing polypeptide was reported, The number of neurons immunoreactive for PACAP increased markedly within the nodose ganglion during a 24-48h culture period, PACAP was found to axonally transported and accumpulated at the site of a crush injury.

另有一个研究,是调查在体外培养的鼠迷走神经中垂体腺苷酸环化酶激活多肽的表达和轴突输送,提出在24-48小时的培养期,PACAP免疫反应性神经元的数目在结节神经节内显著地增加,PACAP参与轴突输送中并堆积在受损部位,在这部位被释放。

Autoimmunity hypothesis of schizophrenia figures schizophrene has a certain degree of immunological functional disturbance,Hypothalmu- pituitary- adrenal axis can produceimmunosuppression. Hydrocortisone,the production of HPA axis,serve as important medium of immunosuppression, so we presume that hydrocortisone possibly induce immunological dysfunction of schizophrene.

精神分裂症的自身免疫假说认为精神分裂症患者存在一定程度的免疫功能低下,而下丘脑-垂体-肾上腺轴功能紊乱被认为是引起免疫抑制作用的主要机制之一,其中皮质醇是免疫抑制作用的重要介质,因此我们推测精神分裂症患者可能存在有皮质醇含量增高有关。

The adrenals at the bottom represent bilateral cortical hyperplasia. This could be due to a pituitary adenoma secreting ACTH (Cushing's disease), or Cushing's syndrome from ectopic ACTH production, or idiopathic adrenal hyperplasia.

位于下方的肾上腺是肾上腺皮质增生,这可能是由于垂体腺瘤分泌 ACTH,或是由于 ACTH 异常分泌引起的库欣氏综合征,还可能是由于先天性肾上腺增生而引起的。

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