垂体的

Isointence signal of neurohypophysis were significantly higher in the Ⅱ type than the Ⅰ type.

型ESS的垂体后叶信号变为等信号的发生率比Ⅰ型高。

But over neurohypophysis IL-4 immunoreactive productions were hardly observed.

推测可能是由于胎儿自身抗排斥能力的提高降低了IL-4在垂体中的分布。

Objective To explore the structural foundation of the releasing pattern and extracellular normal transport route for secretory granules of polypeptide hormones of neurohypophysis.

目的 探讨神经垂体多肽激素分泌颗粒的释放形式和在细胞外正常转运途径的结构基础。

The neurohypophysis is only found in the dorsal region between the RPD and the PPD. The growth hormone cells do not differentiate in the PPD of the adenohypophysis, occupying 2/3 of the PPD until the larva is 5 days old. The other hormone-producing cells in the RPD and in the PT do not differetiate. In the 10-day old larva, the hormone-producing cells except the GH cells in the adenohypophysis do not differentiate. In 15-day old larva, the adrenocorticotropic hormone cells differentiate in the RPD and the other hormone-producing cells in the adenohypophysis do not differentiate. In the 30-day old larva, the all kinds of hormone-producing cells are formed in the adenlhypophysis.

神经垂体只见于RPD和PPD交界的背上方。5日龄仔鱼腺垂体内GH细胞已分化，占PPD的2/3，其他激素分泌细胞未见分化。10日龄仔鱼脑垂体内除GH细胞外，未见其他种类激素分泌细胞分化。15日龄仔鱼脑垂体RPD内ACTH细胞已分化，PPD和PI内除GH细胞外，其他种类激素分泌细胞均未分化。30日龄仔鱼RPD、PPD和PI内各种激素分泌细胞都已分化，共有6种激素分泌细胞，分别是促肾上腺皮质激素分泌细胞，催乳激素分泌细胞，生长激素分泌细胞、促甲状腺激素分泌细胞、促性腺激素分泌细胞和促黑激素分泌细胞。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, which indicates PX and melatonin supplementation have no significant effect on CRH levels.

结果： ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低，提示松果体摘除后下丘脑CRH 神经元的表达增强；②松果体摘除大鼠补充褪黑素后，下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复，不过不论是低剂量组还是高剂量组，也不论是术后4 周还是术后8周，均不能恢复至正常；③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低，提示下丘脑CRH 神经元释放CRH 增加；④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性，表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

Results ①Compared to sham group, ISH and IHC of rat hypothalamic CRHshow positive cells numbers increase, positive areas enlarge and average gray scaledecreases, which reveals the expression of hypothalamic CRH neurons enhances afterPX;②The enhancement of ISH and IHC of hypothalamic CRH in PX rats aftermelatonin supplementation dose-dependently recovers, but it can't return to be normaleither in high dose group or in low dose group and either at 4th week or at 8th week;③IHC of CRH in median eminence of neurohypophysis shows positive areas enlargeand average gray scale decreases, which reveals the releasing of CRH fromhypothalamic CRH neurons increases;④ELISA of CRH in serum shows thedifferences of CRH concentrations among all groups are not significant, whichindicates PX and melatonin supplementation have no significant effect on CRH levels.

结果： ①松果体摘除后大鼠下丘脑室旁核CRH 原位杂交和免疫组化的结果与假手术对照组相比均显示阳性细胞数增多、阳性面积增加、平均灰度降低，提示松果体摘除后下丘脑CRH 神经元的表达增强；②松果体摘除大鼠补充褪黑素后，下丘脑CRH 原位杂交和免疫组化染色增强呈剂量依赖性恢复，不过不论是低剂量组还是高剂量组，也不论是术后4 周还是术后8周，均不能恢复至正常；③松果体摘除后神经垂体正中隆起CRH 免疫组化结果显示阳性面积增加、平均灰度降低，提示下丘脑CRH 神经元释放CRH 增加；④ELISA 法检测血清CRH结果示各组血清CRH 浓度差异没有显著性，表明松果体摘除及补充褪黑素对血清CRH 水平没有显著影响。

The variation scope of standard curve parameter of 12 groups of RIA tests for the eight kinds of pituitary and gonad hormones was basically controlled under 15%.

这8 种垂体性腺激素12 批 R I A 测定的标准曲线参数的变异范围基本控制在15 ％以内。

The aim of the present study is to evaluate the neuroprotective effects of ghrelin on the ischemic penumbra in focal cerebral infraction.

目前关于ghelin对中枢神经系统作用的研究主要集中在下丘脑—垂体系统，而对中枢神经系统其它部位的研究报道尚不多。

AIM: To discuss the use of inferior petrosal sinus sampling in distinguishing between pituitary and ectopic sources of adrenocorti cotropindependent Cushing syndrome.

R%E9X2DD2{；l0 目的：探讨岩下窦静脉取血在鉴别垂体和异位来源的ACTH依赖性Cushing综合征的意义。

This paper describes an inhibitory effert of GABA on the incorporation of￣3H-TdR into rat anterior pituitary cells in static primary monolayer cultures. The action was antagonizable by picrotoxin.

本实验利用原代细胞培养体系，观察到GABA对大鼠垂体前叶细胞的氚标胸苷（3H－TdR）基础掺入率有明显的抑制性效应，且可被印防己毒素所反转。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！