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垂体后叶

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Objective In order to understand the role of IL-6 as a neurotrophic factor owing to increasing of nerve fibers in anterior pituitary after adrenalectomy.

目的 了解肾上腺切除后垂体前叶内神经纤维增多的成因及与神经营养因素的关系。

The pituitary gland consisted of neurohypophysis and adenohypophysis. The adenohypophysis was divided into anterior lobe, intermediate lobe and posterior lobe.

黄颡鱼的脑垂体由垂体神经部和垂体腺部组成,垂体腺部又由前叶、间叶和后叶三部分构成。

Clinical curative effect of hypophysin unite propranolol to healing esophagus fundus ventricularis variceal bleeding is similar with somatostatin, it is first elective method both economy and effective of healing esophagus fundus ventricularis variceal bleeding.

垂体后叶素联合心得安治疗食管胃底静脉曲张破裂出血的临床疗效与生长抑素基本相似,是治疗食管胃底静脉曲张破裂出血的既经济又实用有效的方法。

Clinical curative effect of hypophysin unite propranolol to healing esophagus fundus ventricularis variceal bleeding is similar with somatostatin, it is first elective method both economy and effective of healing esophagus fundus ventricularis variceal bleeding.

垂体后叶素联合心得安治疗食管胃底静脉曲张破裂出血的临床疗效与生长抑素基本相似,是治疗食管胃底静脉曲张破裂出血的既经济又实用有效的方法。中国论文联盟http://www.lwlm.com

Clinical curative effect of hypophysin unite propranolol to healing esophagus fundus ventricularis variceal bleeding is similar with somatostatin, it is first elective method both economy and effective of healing esophagus fundus ventricularis variceal bleeding.

垂体后叶素联合心得安治疗食管胃底静脉曲张破裂出血的临床疗效与生长抑素基本相似,是治疗食管胃底静脉曲张破裂出血的既经济又实用有效的方法。转载于中国论文联盟 http://www.lwlm.com

Methods The model of myocardia ischemia was made by injection of pituitrin in rats. The changes of ECG were observed with three parameters, viz. the heart rate, the locomotions of T wave and S T section.

采用垂体后叶素法建立心肌缺血动物模型,以Ⅱ导联心电图T波和S—T段位移及心率的变化为指标,观察党参和黄芪对实验性心肌缺血大鼠的保护作用。

Results Following orchiectomy 7d,the amount of CGRP-immunoreactive nerve fibers in the AP of the rat increased significantly, with the tortuous varicose fibers more densely distributed than that of NOR and the amount of varicosities increased significantly, while the thick fibers were more thicker than that of NOR,and many thin fibers were sent out from the thick fibers, and the varicosities were more larger.

结果 睾丸摘除7d后,大鼠垂体前叶CGRP免疫反应神经纤维发生了显著变化,表现为膨体型纤维较正常组稠密,分支增多,迂曲成片,盘绕成网,分布更加广泛,膨体数量显著增多;粗纤维较正常组粗,且发出许多迂曲盘绕的细纤维,膨体形态变大。t检验显示,OX组与NOR组垂体前叶内CGRP免疫反应神经纤维的平均面积密度差异显著,OX+V与NOR组差异显著。

RESULTS Ouabain-like immunoreactivities were observed abundantly in the inner zone of adrenal cortex, known as the zone reticularis of SD rats and Macaca mulattas; weakly in the posterior pituitary of SD rats, but nothing in the hypothalamus.

结果 在大鼠和恒河猴的肾上腺皮质内侧网状带细胞中可以观察到丰富的哇巴因免疫反应阳性物质,垂体后叶有较弱的哇巴因免疫反应阳性物质,而下丘脑并未发现有哇巴因免疫反应物质存在。

When aborted rats in group E were treated with the dose of 50 IU/g IFN-γ, expression of TNF-αin this group was compared with the other four groups, the results were as follows: Compared with group A, the nucleus pre-opticus medialis, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, nucleus arcuatus hypothalami and pars intermedia had a highly expression of TNF-α, in the other nuclei of hypothalamus, neurohypophsis and adenohypophysis, the change was not significantly, the expression of TNF-αin follicle and corpus luteum were decreased distinctly, the variation in uterus was slight and no difference was exsited; Compared with group B, the expression of TNF-αin nucleus nucleus lateralis hypothalami, nucleus ventromedialis hypothalami, nucleus arcuatus hypothalami, adenohypophysis and uterus presented a remarkable enhancement, conversely, the TNF-αexpression in the nucleus pre-opticus medialis, nucleus pre-opticus suprachiasmaticus, nucleus supra-opticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, neurohypophsis, follicle and corpus luteum had been significantly decreased; Compared with group C, the nucleus pre-opticus medialis, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, nucleus arcuatus hypothalami, adenohypophysis, pars intermedia and uterus had upregulated the expression of TNF-α, however, it was decreased in the nucleus periventricularis hypothalami and corpus luteum; When compared with group D, the expression of TNF-αin nucleus lateralis hypothalami, nucleus dorsomedialis hypothalami, nucleus ventromedialis hypothalami, pituitary, follicle and ovary stroma were obviously enhanced, while in the nucleus supra-opticus and nucleus arcuatus hypothalami, the situation was definitely opposite, in the other parts, the change was not significant.

外源腹腔注射50 IU/g IFN-γ后,同A组相比:E组TNF-α免疫阳性产物在下丘脑视前内侧核、视前大细胞核、室周核、腹内侧核、背内侧核、弓状核、垂体中间部显著增高,在下丘脑其它核团、神经垂体、垂体前叶较A组差异不显著,在卵泡、黄体中阳性产物表达均较A组显著降低,在子宫中表达较A组变化不明显;同B组相比:E组TNF-α免疫阳性产物在下丘脑外侧核、腹内侧核、弓状核、垂体前叶、子宫均显著增高,在视前内侧核、视交叉上核、视上核、视前大细胞核、室周核、室旁核、神经垂体、卵泡、黄体中阳性物质表达均显著降低;同C组相比:E组下丘脑视前内侧核、腹内侧核、背内侧核、弓状核、垂体前叶与中间部、子宫均显著增高,在室周核、黄体中均显著降低;同D组相比:E组下丘脑外侧核、背内侧核、腹内侧核、垂体各部、卵泡、卵巢基质均显著增高,在视上核、弓状核显著降低,在其它部位表达变化差异不显著。

When aborted rats were injected with 10 IU/g IFN-γin group D, compared with group A, expression of TNF-αinmmuopositive substance in the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami were highly increased, conversely, the ones in the nucleus pre-opticus suprachiasmaticus, neurohypophsis, adenohypophysis, ovary were obviously decreased, the change in the uterus was not remarkable; Compared with group B, expression of TNF-αin the arcuatus hypothalami was obviously enhanced, while in the nucleus pre-opticus suprachiasmaticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, neurohypophsis, pars intermedia, ovary, the results were on the contrary, the uterus had no significantly variation; Compared with group C, expression of TNF-αin the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami, adenohypophysis and pars intermedia had an obviously risen trend, however, the variation in the nucleus pre-opticus suprachiasmaticus, nucleus periventricularis hypothalami, neurohypophsis, pars intermedia, follicle and corpus luteum was completely opposite, uterus had no obviously change.

外源腹腔注射10 IU/g IFN-γ后,同A组相比:D组TNF-α免疫阳性产物在下丘脑视前内侧核、视上核、视前大细胞核、室周核、室旁核、弓状核显著增高,在视交叉上核显著降低,在其它核团较A组无显著差异,在神经垂体、垂体前叶、卵巢中阳性产物表达均较A组显著降低,在子宫中的表达较A组变化不明显;同B组相比:D组TNF-α免疫阳性产物在弓状核显著增高,在视交叉上核、视前大细胞核、室周核、室旁核、腹内侧核、背内侧核、神经垂体、垂体中间部、卵巢各部阳性物质表达均显著降低,在子宫表达变化不显著;同C组相比:D组下丘脑视前内侧核、视上核、室旁核、弓状核、垂体前叶与中间部均显著增高,在视交叉上核、室周核、神经垂体、卵泡、黄体中均显著降低,子宫中表达变化不明显。

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