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RESULTS Asarum and A V compound has remarkable analgestic effect of pain in mice induced by acetic acid and hot plate.

结果 细辛及A V复方制剂对醋酸致小鼠腹痛、热板法致小鼠足痛均有明显的镇痛作用并能抑制蟾蜍坐骨神经动作电位的传导。verapamil有弱的镇痛作用,无坐骨神经动作电位阻滞作用。

Methods: The myelination of the sciatic nerve was measored with light microscope and electron microscope; the expression of p75 in the sciatic nerve was measured by Western blot; the nuclear translocation of NF-kappa B in the sciatic nerve were showed by immunofluorescence.

用光镜和电镜方法检测坐骨神经纤维的髓鞘化情况;用免疫印迹方法检测坐骨神经p75的表达;用免疫荧光方法检测坐骨神经雪旺细胞内核转录因子的表达。

Most sciatic nerve trunk tumors are easy to recur for which radical sugery is the first choice and chemotherapy or radiotherapy is accessory treatment.

坐骨神经干肿瘤的诊断必须进行细致的坐骨神经干的扪诊检查;治疗以根治手术为主,辅以化疗或放疗。

YIQIHUOXUEFANG can relieve the myelin sheathe swollen of the nerves and the disease of the sciatics, and promote local vessel density around the myelin sheathConclusionsYIQIHUOXUEFANG can regulate blood glucose effectively, improve the mico-circulation around the sciatics of the diabetes rats, restrain the metabolism of the multi-alcohol, increase the expressions of the NGFand MBP, i.e.

益气活血方能有效地调节血糖,改善DM大鼠坐骨神经周围微循环,抑制多元醇代谢,有醛糖还原酶抑制剂样作用,升高Na~+-K~+-ATP酶活性,改善和提高神经传导功能,促进坐骨神经神经生长因子和碱性髓鞘蛋白的表达,可明显缓解DM大鼠周围神经的早期病变,有一定的神经修复作用,综合疗效优于弥可保。

Were recorded; the threshold intensity, length of the refractory period and velocity of conduction were measured; the influence of injuries to the conduction was also examined.

分别记录蟾蜍坐骨神经干动作电位的波形,测量蟾蜍坐骨神经干的阈刺激强度、不应期和兴奋传导速度,考察损伤对传导的影响。

Objective Sensory recordings were made in sciatic nerve of rabbits with self-made intrafascicular electrodes to discover more methods on harvesting information of peripheral nerve. Methods Recording electrode fabricated from external insulated wire 60μmin diameter(95%Pt-5%Ir alloy),was implanted directly by microsurgery technique into the fascicle of the sciatic nerve of rabbit.

目的 应用自制神经束内电极采集家兔坐骨神经感觉信号以探索获取周围神经信息的方法方法用显微外科操作技术将直径60μm的95%铂、5%铱合金表面绝缘的金属丝直接插入家兔坐骨神经神经束中作记录电极。

Methods The toad ischiadic nerve was soaked in one of the three local anesthetics: procaine, lidocaine and bupivacaine. The excitability of the toad ischiadic nerve was studied to note the disappearance time of action potential.

分别用普鲁卡因、利多卡因和布比卡因整体浸泡蟾蜍坐骨神经干,分别测定它们对蟾蜍坐骨神经干兴奋性的影响以及兴奋性消失后再恢复的时间。

Result: Schwann-like cells disperse in the hole of nerve graft at oneweek under Scanning Electronic Microscope, the processes of thesatellite-like cells adhere to the wall of graft.There was no statisticaldifference of activity of cells in both group(P>0.05) using MTT. At 12weeks,the result of appearance, histology and TEM were similar, therewere no statistical difference in SFI%, NEP and quantitative analysis ofrecovery rate of myelinated fiber populations, diameter of myelinatedfiber and thickness of myelin sheat.

结果:1w后扫描电镜下可见接种的类Schwann细胞分散在材料表面的孔隙内,细胞形态为星状,细胞突起与支架管壁粘附;MTT法测定细胞活性示神经支架组在各时间点与对照组无显著性差异P>0.05;12w时两组动物坐骨神经外观、组织学光镜观察、透射电镜观察结果相似、两组坐骨神经功能指数恢复率、神经电生理、再生有髓神经纤维计数恢复率、神经纤维直径恢复率、髓鞘厚度恢复率等指标相比无显著性差异(P>0.05)。

There were soluble trophic molecules with relative molecular weight larger than 30 000 for survival and neurite growth of FMN cultures in media with SC-CMCs derived from facial and sciatic nerves of neonatal rats and with SC-CMCs derived from Wallerian degenerating facial and sciatic nerves of adult rats. It might be reasonable to choose SC from sciatic nerves of rats on account of the findings from SC cultures on facial motoneurons.

面神经和坐骨神经SC-CMC中含有促FMN存活、生长的蛋白或多肽,相对分子质量大于30 000,其活性作用与使用的蛋白浓度有关;在研究SC分泌物对FMN营养活性作用时,可考虑选择坐骨神经SC。

P75 expressed only in the injured sciatic nerve,the ipsilateral spinal ganglion and motor neuronal body of spinal cord, not in the normal peripheral nerve system.

P75在坐骨神经损伤一侧的脊髓前角运动神经元胞体、脊神经节感觉神经元胞体和坐骨神经均有表达,而在未损伤的周围神经系统无表达。

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