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Methods The acute necrotizing pancreatitis model was made by retrograde injection of3.5%Sodium Taurocholic Acid into the rat's pancreatic duct.Through mirabilit for external application and qing yi decoction,the changes of serum endothelin,nitric oxide,amylase and the weight changes ofmirabilit for external application and the pathological changes of pancreas,lungs were observed.

应用牛磺胆酸钠逆行胰胆管穿刺注射造成大鼠急性坏死性胰腺炎(acute necrotizing pancreatitis,ANP)模型,通过芒硝外敷与清胰汤内服联合应用,观察大鼠血清内皮素(endothelin,ET)、一氧化氮(nitric oxide,NO)、血清淀粉酶(amylase,AMY)的变化及芒硝外敷前后自身重量的变化和胰腺、肺脏的病理变化。

Cytokines found to have up-regulated in cells were measured in serum and lung tissue of rats exposed to large tidal volume ventilation. For investigating the intracellular pathway of cytokine up-regulation in VILI, exogenous TNF-α or H2O2 was added to culture media of alveolar epithelial cells. Cytokines were then measured. To explore the role of oxidant stress in VILI, N-acetylcysteine, as an anti-oxidant, was used in vitro and in vivo.

我们在体外培养的肺上皮细胞中加入外源性肿瘤坏死因子、过氧化氢或N-乙酰半胱氨酸,观察细胞因子的变化。N-乙酰半胱氨酸亦被投入大鼠呼吸机诱导肺损伤模型,观察用药后细胞因子的变化。

Wagener FA, Eggert A, Boerman OC, Oyen WJ, Verhofstad A, Abraham NG, Adema G, van Kooyk Y, de Witte T, Figdor CG. Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood 2001;98(6):1802-1811.11 McCoubrey WK Jr, Huang TJ, Maines MD.

推测其作用机制可能有以下几个方面:(1)研究证实,在EAE的发生和发展中,有多种炎性细胞因子,如白细胞介素-1、2,肿瘤坏死因子a和干扰素g发挥着重要作用,他们的存在进一步激发了HO-1的表达[17]。

At day 20, some of the acini collapsed, and the epithelial cells of the duct were damaged.

由10μg·L-1 B\P处理20d时,在鳃回血管中发现血细胞坏死后残留的固缩细胞核,鳃丝的上皮细胞排列不规则甚至断裂,部分消化腺泡崩解,鳃丝结构和消化导管上皮结构损害严重;消化盲囊组织结构的损伤比鳃更为严重。

Objective To investigate the expression of CD18 and the tendency of neutrophil in avulsed skin tissues of swine, and to discuss the effect of CD18 on secondary tissues necrosis of skin avulsion injury.

目的:研究猪皮肤撕脱伤组织中整合素CD18的表达及中性粒细胞的趋化,探讨CD18在皮肤撕脱伤组织继发性坏死中的作用。

Objective To observe the change of macrophages in peritoneal cavity, immune function, and TNF-α in peritoneal fluids after a pneumoperitoneum with insufflating carbon dioxide (CO2) or helium in rat model, investigating the effects of different gases on peritoneal local immunity.

目的 研究二氧化碳(CO2)、氦气在模拟气腹条件下,动物模型腹腔巨噬细胞的数量、免疫功能和腹腔液中肿瘤坏死因子-α含量的变化,探讨不同气体对机体腹腔内局部免疫的影响。

The disorderis char-acterized by necrosed upper leaves and by leaf curling,distortion or leaf tip burn Fig.

这种疾病的典型症状是上层叶片出现扭曲、变形或坏死在世界各地种植百合的温室都会经常发现叶烧病的踪迹。

"Based on the incidence results ... and presupposing equal risk distribution, without therapeutic intervention, most patients should theoretically experience at least one episode of avascular necrosis at some point in their life," Dr. Mistry wrote.

Mistry博士指出,基于发生率的结果……以及事先假设的相同风险分布,若不接受任何治疗性干预措施,理论上大部分患者在其生命中的某一时刻至少会发作1次非血管性坏死。

Further study of other polymorphisms in the TNF promoter is indicated to understand more about the tophi.

未来仍然需要有更多关於甲型肿瘤坏死因子的其他位置多型性的探讨,进一步了解痛风石产生的分子机转。

Survival of patients after severe organophosphorous insecticide poisoning is strongly dependent on effective intensive care treatment, as aspiration pneumonia and multi-organ failure are typically the final causes of death in such cases.

严重的有机磷杀虫剂中毒病人能否存活取决于加强护理治疗的有效性,由于吸入性肺炎和多器官坏死是这些情况下导致死亡的最终因素。

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