坏死的

The oral liquid is superior to available medicine and method of treating Duchenne muscular dystrophy in that it has the effects of preventing muscle fiber necrosis, promoting muscle fiber regeneration, strengthening myodynamia, and lowering CPK, LDH and other biochemical indexes.

解决了现有治疗DMD疾病的药物或方法如免疫抑制剂、皮质类固醇类激素、硫唑嘌呤及和环孢霉素A等的缺陷。具有防止肌纤维坏死，促进肌纤维再生，肌力增强，CPK、LDH等生化指标下降，病症明显改善的效果。而姜黄素原来主要用于治疗肿瘤、溃疡、肝炎，以及降血脂、忧郁症等。

BACKGROUND: Ratio of surgical flap in usual is less than or equal to 2:1, and it can be 3:1 in some particular place where has abundant blood supply, the exceeded would necrose.

背景：常规皮瓣设计常遵循长：宽≤2：1的原则，在某些局部血运丰富的区域，可达3：1，超出这个范围，皮瓣的远端易发生坏死。

Treatment temperatures are representative of those required for thermal necrosis of ingrowing nociceptor nerve fibers and disc cellularity alone, or with coagulation and restructuring of anular collagen in the high temperature case.

治疗温度代表那些需要热坏死处理的内生的伤害感受器神经纤维以及间盘细胞构成，或者在高温下造成胶原环的凝固和重构。

Treatment temperatures are representatie of those required for thermal necrosis of ingrowing nociceptor nere fibers and disc cellularity alone, or with coagulation and restructuring of anular collagen in the high temperature case.

治疗温度代表那些需要热坏死处理的内生的伤害感受器神经纤维以及间盘细胞构成，或者在高温下造成胶原环的凝固和重构。

The results indicated that the typical apoptosis was induced by PRRSV in lungs and uteri. The ultrastructural changes showed different characterizations at different stages of the infection. During the early stage from 8th h to day 3 postinfection,the apoptosis cells shrank,the cytoplasm concentrated,the chromatin condensed,the kernel disaggregated and the endoplasmic reticulum dilated. During the middle stage from day 5 to day 9 postinfection,the apoptosis cells evidently shrank,the cell membranes protu berated,the plastosome manifolded,and apoptosis bodies were found. During the last stage from day 10 upwards postinfection,the apoptosis bodies degenerated and disappeared,and no inflammation occurred. Few apoptosis cells were necrotic.

结果表明，PRRSV可诱导宿主肺和子宫发生典型的细胞凋亡，表现为细胞的超微形态结构随着病毒感染进程出现不同的特征性变化，早期（感染后第8 h至第3 d）凋亡细胞多表现为细胞体积缩小，细胞质密度增强，染色质浓缩，核仁解体，内质网扩张；中期（感染后第5 d至第9 d）凋亡细胞体积显著缩小，细胞膜突起，线粒体增多，有凋亡小体形成；晚期（感染后第10 d以后）凋亡细胞形态多表现为凋亡小体降解和消失，少数凋亡细胞在凋亡晚期表现为坏死细胞。

Electron micrograph showed us that hepatocytes were damaged seriously along with the prolonged NHBD time in A group. At the NHBD 120 and 150min in A group, hepatocytes showed numerous cytoplasmic vacuoles and lysosomes, round swollen mitochondria with clear matrix and rough endoplasmic reticula which was not in a stacked arrangement.

电镜发现，A组随着心跳停搏时间的延长，肝细胞的损伤逐渐加重，至120和150min时，肝细胞内可出现大量空泡和溶酶体，线粒体和粗面内质网结构也遭到破坏，但未出现明显的坏死和凋亡改变。

The expression changes of TNF-α and p65 mRNA expression were detected by reverse transcription-polymerase chain reaction, the TNF-α level in the supernatant was determined by ELISA, and the expression of p65 in AR42J cell lines was detected by Stept Avidin-Biotio Complex.

逆转录－多聚酶链反应半定量法观察肿瘤坏死因子/p65亚单位mRNA表达的变化；ELISA法检测TNF-α在细胞上清中质量浓度的变化；链酶亲和素－生物素－过氧化物酶复合物法检测p65蛋白在AR42J细胞中的表达。

The patients were treated with reversal flow axial composite auricular island flap based on supraorbital artery or supratrochlear artery.results6 cases were treated with the technique, only one case underwent epidermal blisterand, and the partial skin flap necrosis, the necrosis area of flap was 1.0cm×2.0cm, 5 cases were successfully repaired with satisfactory.conclusionthe island flap could be an ideal way for the one stage reconstruction of large alar defects, which is recommended to be widely used.

结果：在临床上将该方法应用于6例病人，除1例出现表皮水疱，后皮瓣部分坏死，面积约1.0 cm×2.0，其余5例取得满意的临床效果。结论：反流轴型的耳廓复合组织瓣能ⅰ期修复大面积鼻翼缺损，是一项极具推广的修复手段。

Severity of joint swelling, radioimmunoassay of serum estradiol (E 2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once we...

结果：切除卵巢的小鼠，血中雌二醇水平明显下降，而血清骨钙素和肿瘤坏死因子的含量则显著增加；同时，滑膜组织炎症加重，软骨损伤及骨的破坏均更为严重。

Methods: The mice for experiment were immunizied with subcutaneous injection of type Ⅱ collagen to induce arthritis after ovariectomy. Severity of joint swelling, radioimmunoassay of serum estradiol (E2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once weekly.

切除小鼠卵巢后，Ⅱ型胶原皮下注射以诱导关节炎；每周1次观察小鼠的关节肿胀程度；组织切片光镜下观察小鼠滑膜、关节软骨及骨的改变；放射免疫法检测小鼠血清雌二醇、骨钙素、肿瘤坏死因子的变化。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！