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The neural histology shows that the degeneration, necrosis and reduction of the quantity of the neur cell on anterior horn cinereum, the change on lateral cord white matter demyelination, disorder, disruption of the neuraxon. The entire changes is in conformity with pathological character of the CSM.

神经组 织学检查见到灰质前角神经元的变性、坏死、数量减少,以及侧索白质脱髓鞘变,排列紊乱,轴突断裂,病理变化符合CSM 的病理变化特征。

This type of infarction is marked by loss of neurons and neuroglial cells and the formation of a clear space at the center left.

左侧中央的明亮的坏死区神经元和神经胶质细胞消失。

Results:The rate of tumor shrinkage and necrosis was 46.8% and 20.7%,while the contrast group was 78.9%,49.2% respectively(P<0.05).There were significant difference(P<0.05)for 2year survival rate in singlelesion group,nondistant metastasis group and combinedtherapy group.

结果:单纯TACE组的肿瘤总缩小率和肿瘤完全坏死率分别为46.8%和20.7%,联合治疗组分别为78.9%、49.2%(P均<0.05),单病灶组、无转移灶组及联合治疗组的2年生存率高于多病灶组、有转移组和单纯TACE组(P均<0.05)。

AIM: To observe the regulative effects of different concentrations of glucose on the expressions of tumor necrosis factorrelated apoptosisinducing ligand,osteoprotegerin,and the ligand of osteoprotegerin in osteosarcoma MG63 cells,and to study the role of nonphysiological concentration of glucose in pathogenesis of diabetic osteoporosis.

目的:观察不同浓度葡萄糖环境下人成骨肉瘤MG63细胞株肿瘤坏死因子相关凋亡诱导配体及其护骨素、护骨素配体的表达,探讨糖尿病骨质疏松症的发病机制。

N Dq'^8z?1I3q AIM: To observe the regulative effects of different concentrations of glucose on the expressions of tumor necrosis factorrelated apoptosisinducing ligand,osteoprotegerin,and the ligand of osteoprotegerin in osteosarcoma MG63 cells,and to study the role of nonphysiological concentration of glucose in pathogenesis of diabetic osteoporosis.

目的:观察不同浓度葡萄糖环境下人成骨肉瘤MG63细胞株肿瘤坏死因子相关凋亡诱导配体及其护骨素、护骨素配体的表达,探讨糖尿病骨质疏松症的发病机制。

After excision of the fibrotissues and necrotic bone in the fracture ends, cancellous bone was transplanted in it and fixed by a plate. Then, the fracture ends were enclosed by a Facial Pedical osteal Flap.

将骨折端纤维及坏死骨去除之后,局部给以松质骨植骨并行钢板固定,之后将所取的筋膜蒂骨膜瓣包紧固定在骨折端周围,观察骨不连术后骨折的愈合情况。

It has important sense for the research of this disease to establish animal models with osteonecrosis of the femoral head.

股骨头坏死动物模型的建立对该病的研究有重要意义。

But the pathophysiology of osteonecrosis of the femoral head has not been completely elucidated.

目前认为激素和酒精的摄入是股骨头缺血坏死最常见的两大病因。

The most common continuousfoci were pneumonia (41.3%), tracheobronchitis (28.9%), peritonitis(23.4%), uterine/ovarial necrosis (9.8% of female patients),intraabdominal abscesses (9.1%), and pyelonephritis (6%).

最常见的持续性病灶是肺炎(41.3%)、气管支气管炎(28.9%)、腹膜炎(23.4%)、子宫/卵巢坏死(9.8%的女性病人)、腹内脓肿(9.1%)和肾盂肾炎(6%)。

Methods The PCO rat models, prepared by pregnancy hormone combine with human chorionic gonadotrophin, randomly divided into four group as control, model, Chinese crude drug and western medicine group; The levels of serum gonadal hormone were detected by radioimmunoassay; The effects of ZYC on ovaries and ovarial follicular development were observed by light microscope; And the expression level of TNF-α was detected with the immunohistochemical staining technique.

采用孕激素联合人绒毛膜促性腺激素造模法制备PCO模型大鼠。随机分为对照组、PCO模型组、PCO模型组+助孕胶囊组、PCO模型组+克罗米酚组,运用放免法测定血清性激素水平的变化;光镜观察卵巢、卵泡发育的影响,免疫组化学法检测卵巢组织肿瘤坏死因子α表达水平。

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