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Moreover, the heterozygote is refrigerated at low temperature or frozenly reserved in liquid nitrogen for a long time, and after resuscitation, the heterozygote can be directly used in the repair of tissues or organs so as to effectively avoid the necrosis of tissues due to untimely use after assembling.

然后在低温下泠藏或在液氮中长期冻存,复苏后可直接用于组织或器官的修复,有效避免了细胞在组装后若不及时使用就会出现的坏死现象。

OBJECTIVE: To investigate the effect of Jiangu granula on the apoptosis of rat osteoblast induced by TNF-ɑ.

目的:验证健骨颗粒含药血清对肿瘤坏死因子α诱导的鼠成骨细胞凋亡的影响。

Objective To explore the role of tumor necrosis factor-α in the pathogenesis of hepatorenal syndrome.

目的 探讨肿瘤坏死因子-α及肝素对内皮素-1(ET-1)收缩肾脏血管作用的影响,研究TNF-α在肝肾综合征发病机制中的作用。

To investigate the role of inflammatory cytokines in the pathogenesis of lung ischemia-reperfusion injury,the rat ischemia model with occlusion of left hilus for 45-minute was set up and the changes of levels of TNFα,IL-6 and IL-8 in lung tissues and plasma were dynamically observed during lung ischenia-reperfusion.

为探讨炎性细胞因子在肺缺血再灌注损伤发病机制中的作用,采用大鼠在体温缺血再灌注模型,动态测定了肺组织和血浆肿瘤坏死因子α、白介素-6(IL-6)和白介素-8(IL-8)含量的变化。

Histiocytic necrotizing lymphadenopathy (Kikuchi's disease) is a rarely observed clinical entity characterized by fever and solitary or multiple lymphadenopathy predominantly in the posterior cervical region.

组织细胞坏死性淋巴病变(Kikuchi's disease,菊池氏病)为一种罕见的以发烧及主要侵袭后颈部单一性或多发性淋巴病变为特徵的临床疾病。

In conclusion, Kikuchi-Fujimoto disease can masquerade as a single, rapidlygrowing, parotid tumor in a middle-aged man. Because it is histiocytic necrotizing lymphadenitis adjoining the parotid gland, Kikuchi-Fujimoto disease should be considered a cause of parotid tumor.

经此案例可知,菊池-藤本氏病可以单一、快速增大,发生在中年男性且以疑似腮腺肿瘤为表徵,实际上是邻近腮腺的组织发生了组织球性坏死性淋巴结炎,故临床上耳下附近的疑似腮腺肿瘤病灶,应将本病列入鉴别诊断。

Active viral replication and histologically proven liver necrosis are risk factors for progression to cirrhosis.

病毒复制活跃和组织学已证实的肝组织炎症坏死是慢性肝炎向肝硬化进展的高危因素。

Microscope examination:in group a,at 2 weeks,a few inflamatory cells appeared in the holes with many osteoblasts and ostoid appeared around the drilled holes.at 8 weeks,marrow formed in the drilled holes in group b,at 2 weeks,there were a large amount of osteoblasts in the drilled holes and some ostoid formed around thc drilled holes.at 4 weeks,the drilled holes were full of trabeculae.at 8 weeks,the trabeculae matured with the marrow appeared in the intertrabecular space.

组织学结果:2周时a组钻孔区出现少许炎症细胞,边缘出现较多成骨细胞并有骨组织形成,至8周时,钻孔区内形成骨髓组织,只在边缘形成骨小梁结构。2周时b组钻孔区有大量的成骨细胞,边缘有较多骨组织形成,4周时钻孔区内充满新生骨小梁结构,8周时钻孔区内骨小梁成熟,小梁有骨髓组织填充。[结论]骨髓基质干细胞对兔股骨头缺血性坏死有良好的修复作用。

After model reproducing, the rabbits were randomized to receive a directly intramyocardial injection of either pcDNA3-bFGF 100μg (n=19) or pcDNA3 100μg (n=18). Animals were sacrificed 2, 6 or 12 weeks later, immunohistochemistry analysis was performed to study expression of bFGF gene at protein level, histologic analysis was performed to evaluate the effect of angiogenesis induced by gene therapy.

模型制备成功后将动物分为治疗组(n=19)和对照组(n=18),并于心肌内分别注射pcDNA3-bFGF100μg或pcDNA3 100μg,饲养至2、6、12周处死;免疫组化观察蛋白表达;行病理切片观察缺血坏死心肌面积的变化和缺血心肌内血管新生的情况。

ResultsThe glandular cell in the endometrial implant after therapy with middle or high-dose of (10,15 gkg-1d-1) XiaoChaiHu Decoction showed characteristic features of apoptosis which displayed by the cell decreased in size, karyopyknosis , cytoplasmic and nuclear chromatin condensation , density increased and a lot of apoptotic bodies among cell. Whereas some stromal cell displayed degeneration and necrosis. The protein expression of Fas and Caspase-3 in endometriotic tissue of XiaoChaiHu Decoction group was higher than that in the endometrium.

结果中、高剂量小柴胡汤(10,15 gkg-1d-1)治疗后,异位内膜有较多腺上皮细胞出现凋亡的特征,表现为细胞体积变小,核固缩,胞浆和核染色质凝集,密度增高,细胞间凋亡小体,同时间质细胞中可见一些坏死细胞;异位内膜Fas蛋白、Caspase-3蛋白的表达水平明显高于其在位内膜。

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