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We propose an outpatient procedure under local anesthesia for the correction of prominent ears. We fold the antihelix with an anterior scoring method via posterior approach. The cartilage is preserved to avoid a sharp antihelical fold, and the scar is concealed in the posterior auricular sulcus. All patients had satisfactory correction of the deformity and yet no significant complication.

我们经由耳朵后将对耳轮软骨前表面作一个网状的雕刻,然后将之向后翻转作为新的对耳轮,可以避免软骨切除后所产生不美观的转折,避免产生两耳不对称的情形,术后没有血肿或皮肤坏死的并发症,手术所产生的疤痕隐藏在耳朵后面,所有的病人对手术结果都很满意。

We propose an outpatient procedure under local anesthesia for the correction of prominent ears. We fold the antihelix with an anterior scoring method via posterior approach. The cartilage is preserved to avoid a sharp antihelical fold, and the scar is concealed in the posterior auricular sulcus. All patients had satisfactory correction of the deformity and yet no significant complication.关键词 prominent ears , otoplasty

我们经由耳朵后将对耳轮软骨前表面作一个网状的雕刻,然后将之向后翻转作为新的对耳轮,可以避免软骨切除后所产生不美观的转折,避免产生两耳不对称的情形,术后没有血肿或皮肤坏死的并发症,手术所产生的疤痕隐藏在耳朵后面,所有的病人对手术结果都很满意。

On postnatal Day 5, wild-type mice and mice lacking alpha2A-adrenoceptor (alpha2A-KO) or alpha2C-adrenoceptor subtypes (alpha2C-KO) were randomly assigned to receive dexmedetomidine (3 microg/kg) or phosphate-buffered saline intraperitoneally. Thirty minutes after the intraperitoneal injection, the glutamatergic agonist ibotenate (10 microg) was intracerebrally injected, producing transcortical necrosis and white matter lesions that mimic perinatal human hypoxic-like lesions.

将出生后5天的野生型大鼠和缺乏α2A(α2A-KO)或α2C(α2C-KO)肾上腺受体亚型的大鼠腹膜内随机注射右旋美托咪啶(3 μg/kg)或磷酸钠缓冲液。30分钟后,脑内注射10μg 谷氨酸激动剂 ibotenate ,产生类似围产期缺氧性皮质坏死和白质损伤。

Aside from pancreatic enzymes activiation and autodigestive process, recent investigations have established that the upregulation of inflammatory mediator are believed to be the critical steps in the progression of mild pancreatitis to severe pancreatitis. Tumor necrosis factor-, ThyomboxaneA2 ,ProstaglandinsI2 are all important inflammatory mediator. TNF-( is one of cytokines. It is important to the over-production of ICAM-1,VCAM-1, TXA2 andPGI2. The ICAM-1 and VCAM-1 mediate both leukocytes adhesion and migration through the endothelium into tissues to connect with injuried target cells. The TXA2 and PGI2 are the production of arachidonic acid. They are responsible for the tissue ischaemia.

肿瘤坏死因子(Tumor necrosis factor-, TNF-、血栓素A2(ThyomboxaneA2,TXA2),前列环素(ProstaglandinsI2,PGI2)均是炎症反应中重要的炎性介质,其中肿瘤坏死因子-是非常重要的细胞因子之一,它由活化的单核细胞产生,在细胞间黏附分子(Intercellular adhesion molecule-1,ICAM-1)及血管细胞黏附分子(Vascular cell adhesion molecule-1,VCAM-1的表达、血栓素A2及前列环素过量生成方面起着重要的作用,前两者是介导白细胞与内皮细胞黏附,迁移于组织并与受损的靶细胞相结合的主要媒介,是炎症反应中的重要介质,后两者是花生四烯酸的代谢产物,亦是重要的炎性介质,参与构成血液循环障碍。

Results The main CTimages of adrenal neuroblastoma in children were bigger extrarenal tumor ,included :huge and irregular mass(6 cases ),regular mass (2 cases),calcification (87cases),cystic degeneration or necrosis (1cases),bleeding(2cases),crossing of the midline (5cases),wrapping retroperitoneal major vessels (4cases),retroperitoneal enlargement of lymphnode (7 cases),The masses were heterogeneous enhancement.

分析2004年10月~2008年10月经手术病理证实的8例儿童肾上腺神经母细胞瘤的CT表现,如形态,密度及周围结构变化情况,结合临床资料,进行综合评价。结果儿童肾上腺神经母细胞瘤为肾外体积较大肿块,其中不规则肿块6例,规则2例,钙化7例,囊变坏死1例,出血2例,越过中线5例,包绕腹膜后大血管4例,腹膜后淋巴结肿大7例,肾脏向后外侧移位6例。

The mean ADC value of lymphomatous, metastatic and benign lymph nodes was (0.874±0.17)×10~(-3)mm~2/s,(0.98±0.09)×10~(-3)mm~2/s and (1.20±0.10)×10~(-3)mm~2/s. There was statistically different between benign lymph nodes and other groups (P=0.00). When an ADC value of 1.085×10~(-3)mm~2/s was used as a threshold value for differentiating malignant from benign lymph nodes, the best results were obtained with an sensitivity of 87.8% and specificity of 91.3%. 16 of 18 cases (88.9%) were accurately staged in accordance with clinical staging. For 24 patients after chemotheraphy or radiotheraphy, 4 cases were complete remission and WB-DWI was negative. WB-DWI was positive in 14 of 17 cases with recurrent or remnant tumor. For 3 patients with suspected partial remission, WB-DWI indicated necrosis in 2 cases and inactive in 1 case. Repeated WB-DWI examination was performed in 13 cases, tumors were eradicated in 6 cases, improved in 4, expanded in 2. A new colon carcinoma besides its primary lesion was found in 1 case. The results of WB-DWI were all concordant with other clinical tests.

以ADC值1.085×10~(-3)mm~2/s作为诊断恶性淋巴结病变的临界值,敏感性及特异性分别为87.8%和91.3%。88.9%(16/18)患者WB-DWI检查后分期与临床分期一致。24例淋巴瘤患者放化疗后行WB-DWI检查,4例临床疗效为完全缓解,WB-DWI检查均为阴性,17例临床确认有肿瘤复发及明显残留,WB-DWI显示为阳性的14例,另外3例常规影像评价为部分缓解的患者,WB-DWI检查提示2例病灶以坏死液化为主,1例病灶无明显活性。13例淋巴瘤患者行多次WB-DWI检查,发现6例治疗后病灶消失,4例缓解,1例原发病灶缓解,新出现结肠癌,2例淋巴瘤进展,皆与临床相符。

At 48h to 96h PI, proliferative inflammation was observed. All the time, the nonsuppurative encephalitis was observed in the brain.

感染雏鸭的肝组织在接种后24h表现出血性坏死性肝炎变化,接种后48~96h呈增生性病变,而接种后各时期脑组织均呈非化脓性脑炎变化。

The results indicated that the typical apoptosis was induced by PRRSV in lungs and uteri. The ultrastructural changes showed different characterizations at different stages of the infection. During the early stage from 8th h to day 3 postinfection,the apoptosis cells shrank,the cytoplasm concentrated,the chromatin condensed,the kernel disaggregated and the endoplasmic reticulum dilated. During the middle stage from day 5 to day 9 postinfection,the apoptosis cells evidently shrank,the cell membranes protu berated,the plastosome manifolded,and apoptosis bodies were found. During the last stage from day 10 upwards postinfection,the apoptosis bodies degenerated and disappeared,and no inflammation occurred. Few apoptosis cells were necrotic.

结果表明,PRRSV可诱导宿主肺和子宫发生典型的细胞凋亡,表现为细胞的超微形态结构随着病毒感染进程出现不同的特征性变化,早期(感染后第8 h至第3 d)凋亡细胞多表现为细胞体积缩小,细胞质密度增强,染色质浓缩,核仁解体,内质网扩张;中期(感染后第5 d至第9 d)凋亡细胞体积显著缩小,细胞膜突起,线粒体增多,有凋亡小体形成;晚期(感染后第10 d以后)凋亡细胞形态多表现为凋亡小体降解和消失,少数凋亡细胞在凋亡晚期表现为坏死细胞。

Methods A retrospective analysis was performed in 14 cases of urinary obstruction among 1090 cases of transplanted kidney in the year 2000-2006, including 9 cases of vesicoureteral anastomotic stricture, 6 of whom received a second vesicoureteral anastomosis, one had infection surrounding the renal graft and ureter end necrosis, two ureteral anastomosis with bladder muscle flap, and one stenostomia aerocyst distention under ureteroscope.

回顾总结2000-2006年我院1090例肾移植患者中的14例移植后上尿路梗阻患者,其中输尿管膀胱吻合口狭窄9例,6例行膀胱输尿管二次吻合手术,1例移植肾周感染输尿管末段坏死采用移植肾近端新鲜存活输尿管与自体输尿管吻合,1例采用膀胱肌瓣代移植输尿管,1例采用输尿管镜下气囊扩张后放置双J管。

There were broken hyphae and destruction of cells after 1 week, coagulation and necrosis after 1 month.

服特必萘芬1周后病甲中的真菌可见菌丝断裂,胞壁破坏。1个月后见凝固、坏死。

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