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The expression level of metabolitic enzyme (CYP1A1, CYP1B1) and its correlation with cell differentiation /apoptosis were studied as well. The influence of resveratrol in cell cycle was determined with FCM. Results 1 Resveratrol not only suppresses the growth of medulloblastoma cells in a dose and time related fashion but also induces cell differentiation and apoptosis. Resveratrol promotes differention of UW228-1,-2 cells to forward glia, UW228-3 and Med-3 cells to neuron. A treatment of resveratrol in the concentration of 100μM for 48hrs comit most of cells die of apoptosis. 2 Among the four cell lines Fas and Caspase-3 were constantly expessed, whereas FasL was absent irrespective to the drug treatment. 3 ICC, RT-PCR, Western-blot hybridization and EROD enzymatic activity assay demonstrated that expression of CYP1A1 is different after treatment with resveratrol in four cell lines, up-regulated in three UW228 cell lines in a dose dependent manner but down-regulated in Med-3 cells. Suppressive effect of resveratrol on CYP1B1 expression is the same among four medulloblatoma cell lines. 4 Cell cycle distribution of UW228-3 was greatly changed after treatment.

结果:1、白藜芦醇以时间和剂量依赖性方式抑制髓母细胞瘤细胞生长,同时促进细胞的分化和凋亡:白藜芦醇促使UW228-1、-2靶细胞向神经胶质细胞方向成熟分化,UW228-3、Med-3细胞向神经元细胞方向成熟分化,以100μM作用48小时效果显著;2、四个细胞系均有Fas和Caspase-3表达,但无Fas-L基因表达和蛋白活性产生,因此难以形成Fas相关性死亡通路;3、白藜芦醇处理前后CYP1A1基因的表达在各细胞系略有不同:UW228-1,-2,-3三个细胞系白藜芦醇以剂量相关性方式上调CYP1A1的表达,而Med-3细胞系,白藜芦醇却抑制CYP1A1的表达;四个细胞系在白藜芦醇处理后CYP1B1的表达均受到抑制;4、UW228-3细胞系经白藜芦醇作用后细胞周期有较大改变,表现在G0/G1期在整个细胞周期中所占的比例增加,而其它时期则相应减少。

The pore capacity is becoming smaller with increasingthe vitrinite content. 2. Micro-porosity is dominated in the total pore capacity, which takes more than50%. There is not relationship among pore capacity and specific surface with otherfactors such as Maceral and R0, which shows that the distribution and shapes of poreare not influenced by the composition of the coal. 3. The pore is opened for the coal of Ordos Basin, the order is from durain to clarainthen samples to vitrain. Others are belong to half-opened and thin throat. 4. The adsorption content of gas is increasing with the higher pressure, and the freegas content is decreasing;The adsorption content of gas is decreasing with thehigher temp, and the free gas content is increasing;The adsorption content of gas isincreasing with higher vitrinite content for the kennel coal when temp.

总空隙主要由小孔孔容构成,小孔孔容占了50%以上;镜质组含量和惰性组含量等物质以及镜煤反射率均与孔容、比表面未表现出明显的相关性,说明孔隙分布特征不受物质组成的影响 3、鄂尔多斯地区的空隙呈现开放状态为主,空隙开放的次序为暗煤-亮煤-煤样-镜煤,其他盆地则为半封闭和细瓶颈空隙 4、随压力增加,煤对气体的吸附量增加,煤中所含游离气的量随之减小;随温度增加,煤对气体的吸附量减小,而煤中所含游离气的量随之增加;在相同的温压条件下,同是长焰煤的样品,吸附量在孔容中所占的比例随镜质组含量增加而增加。

I am saved at that time " examine immediately " basic characteristic is: 1Of.1POCT cover a range wide, the testing instrument model of same item amounts to 7~8 to plant. 1.2POCT all is placed in clinical the outpatient service of each division, emergency call and ward, the apparatus is almost entire by groom without POCT operation post already card, lack again examine the operation of the member that be not identifier of basic knowledge. 1.3POCT assures measure without quality, examine the specimen is collected, reagent is purchased and save all compare optional, be opposite extremely between the instrument experiment, do not have room endoplasm to accuse already at ordinary times, do not have again judge character between the room, examine quality is in nobody to run state. Of 1.4POCT detect result error is big, repeatability of partial instrument result is poor, the hospital examined 2002 3 hospitals selectived examination randomly in division quality assessment, 45 second large biochemistry appearance detects contrasting POCT blood sugar, its written guarantee...

当时我省"即时检验"的基本特征是:1.1POCT的覆盖面广,同一项目的检测仪器型号多达7~8种。1.2POCT均放置在临床各科的门诊、急诊和病房,仪器几乎全由既无POCT操作岗位培训证,又缺少检验基本知识的非检验人员操作。1.3POCT没有质量保证办法,检验标本采集、试剂采购和保存均比较随意,仪器间无比对试验,平时既无室内质控,又无室间质评,检验质量处于无人管理状态。1.4POCT的检测结果误差大,部分仪器结果重复性差,2002年医院检验科质量考核中随机抽查了3所医院,45例次有大型生化仪检测对照的POCT血糖,其结。。。

A schematic model was proposed to illustrate the occurrences of various lithologies and lithofacies associations. The erosional surfaces on siliciclastic mudstones, funnel-shaped structure, and the exhuming of massive cold-seep carbonates exposed might have been occurred concurrently during a tectonic unstable time in SW Taiwan. The deposition of fossiliferous mudstone interfingered with the conglomerate lithofacies, and represented the rapid facies transition from siliciclastic (non-carbonate) into carbonate environment.

综合岩相观察结果,建构一个符合台湾西南部更新世珊瑚礁与基底泥岩接触关系的沉积相模式;其中,基底泥岩顶部的不规则冲蚀面、充填碳酸盐胶结泥岩砾与碳酸岩烟柱的漏斗状沉积,以及块状冷泉碳酸盐岩的出露,可能均为区域地质构造活动时期所造成;至於与含化石泥岩同时沉积的砾岩相,可能均为基底泥岩在快速浅化的过程中所沉积,标志古环境由矽质碎屑快速转变为碳酸盐环境的过程。

Its main features are: algae body as a single cell or even into a variety of groups; cell walls composed of silica and pectin, but also by the structure of the shell and the shell under the combined set of the Cheng, vertical section view was "soap-box"-shaped; in the upper and lower shell surface of the shell are patterns arranged in patterns on both sides of the main mode of symmetry and radial symmetry is divided into two categories, for the classification of the most important basis; be able to campaign Type in the shell has a shell side seam, can not be changed no shell seam types; pigment body sheet or ribbon, 1 or 2, or for multiple small discoid, yellow green or brown, containing chlorophyll a, c, also contains fucoxanthin and silicon A flavin and other photosynthetic pigments; storage material mainly for oil droplets; reproduction mainly for cell division and cell division in diatoms obvious features are: each cell division, resulting from two sub-cells,, only one and the mother cell and so big, the other one is smaller.

其主要特征是:藻体为单细胞或连成各式群体;细胞壁由硅质和果胶质组成,而且在结构上都是由上壳和下壳套合而成,纵断面观呈"肥皂盒"形;在上下壳的壳面上有花纹,花纹排列的方式主要分为两侧对称和辐射对称两大类,为分类上的最重要依据;能运动的种类在壳面都有壳缝,不能动的种类均无壳缝;色素体片状或带状,1个或2个,或为多个小盘状,黄绿色或黄褐色,含叶绿素a、c,还含有墨角藻黄素和硅甲黄素等光合色素;贮藏物质主要为油滴;繁殖方式主要为细胞分裂,硅藻的细胞分裂的明显特点是:每次细胞分裂所产生的2个子细胞中,仅有1个和母细胞等大,另1个则稍小。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括:遗传学方面的基因多态性和基因突变,二者均是2型糖尿病合并心血管疾病的一个易感因素,内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成;免疫复合物的形成可加速动脉壁的破坏;蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

The result indicates that spore germination shapes prothallium at keeping wet, cortrolling temperature and covering with 75% shading rate.

结果表明:在保湿、控制温度、覆盖遮光率为75%的遮阳网的条件下孢子发芽率高,能正常形成原叶体,继续培养均能进入有性世代形成孢子体幼苗,其中在山林腐殖土和壤土按1:1的比例混合的基质上最适于孢子萌发和幼苗生长,出苗量可达3500株/m2;在杭州采集的紫萁孢子萌发后形成的原叶体、孢子体均比在湖北民族学院采集的耐高温性好。

After selective extraction, the cyst wall of two kind of resting cysts displayed a filament network. In the resting cysts of Tachysoma pellionella and Euplotes encysticus, the filament was located in mesocyst and endocyst respectively. On the other hand, a special filament scaffold region was observed below the cyst wall in two kind of cysts. Compared with the true IF which was located in central part of cyst, the filament of this region was net as well as uniform, and no any cytoplasm residue can be seen in this region. In the resting cyst of Euplotes encysticus, a filamental boundry which partitioned the special filament scaffold region and the true IF region was observed.

两类休眠包囊的包囊壁经生化分级抽提后均显示纤维结构,急纤虫休眠包囊中纤维定位于中间层,包囊游仆虫休眠包囊中纤维定位于内层壁;其次,在两类休眠包囊的包囊壁下,相当于细胞质表质层的位置,均有一个特殊的纤维网络区,与细胞质深层的网络区相比,此部分的纤维纯净、均匀,未见附着细胞器及细胞质残留物,在包囊游仆虫休眠包囊中此纤维网络区与真正的细胞质纤维网络之间由纤维构成的界膜隔开。

The paper studied the scavenging active oxygen radicals of brown pigment from chestnut shell. The results showed that the brown pigment had scavenging effects on hydroxyl radical, superoxide anion radical and aliphatic radicals on lipid-peroxidation. In the range of test concentration, the maximum scavenging or inhibition rate of the brown pigment to hydroxyl radical generated by Fenton reaction, superoxide anion radical generated by illuminating riboflavin system and linoleic acid auto-oxidation was 83.0%, 82.1% and 88.5% respectively.

从清除羟基自由基和超氧阴离子自由基、抗脂质过氧化以及还原能力等方面对板栗壳棕色素的抗活性氧自由基进行了试验研究和评价,结果表明:板栗壳棕色素对Fenton反应产生的羟基自由基和光照核黄素产生的超氧阴离子自由基均具有较强清除作用,对脂质过氧化过程中产生的脂自由基和脂过氧化自由基有明显的抑制作用,且在试验浓度范围内,其最大清除率或抑制率分别可达到83.0%、82.1%和88.5%。

The results showed that the sheep had fibrinous pneumonia and lymphocyte interstitial pneumonia, which were typical pathologic changes of this disease. Remarkable changes were observed in the lung: fibrinous exudates, infiltration of inflammatory cells, pleura thickening, interstitial edema, hemorrhage and formation of thrombiand lymph clot. The heart, liver and kidney had different degeneration degree. Reactive hyperplasia presented in bronchales lymphonodi.

结果发现该病例具有胸膜肺炎的典型病理变化,呈现纤维素性肺炎和淋巴细胞性间质肺炎,纤维素性物质的渗出和炎性细胞的浸润很明显,肺胸膜增厚,同时在肺间质还可见水肿、出血、血栓和淋巴栓的形成;另外心、肝、肾也均有不同程度的变性,淋巴结呈反应性增生。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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