均质的

The level of ADAR gene expression was expressed as ratio expression rate of ADAR gene /β-actin acc...

ADAR3在正常人脑胶质细胞及苯乙酸处理前后的胶质瘤细胞中，均未见表达。结论ADAR2 mRNA水平高表达，可能与高恶性度胶质瘤的发生有关。

The presence of REE tetrad effects in apatites and whole rocks of S-type granites has been reported by Sha and Chappell (1999) and Zhao et al.(1999), respectively. The REE tetrad effect in minerals, such as apatite, spessartite, beryl, alkali feldspar and spodumene, from all zones of Altay No. 3 pegmatite has been found remarkable, and the fractionations among isovalent incompatible elements in these minerals are also significant. This paper puts forward that the REE tetrad effect is one of the basic features of peraluminous melts and the origin of REE tetrad effect might be probably related to some processes prior to the formation of pegmatite magma. The immiscibile liquid separation between silicate melt and hydrosaline melt may be responsible for it.

由于阿尔泰3号伟晶岩脉各带磷灰石以及与其共生的石榴石、绿柱石、碱性长石、锂辉石矿物均存在明显的稀土"四重效应"以及相同电价、相似离子半径的不相容元素间存在显著的分异，并结合最近赵振华等(1999)和Sha and Chappell(1999)报道S型花岗岩全岩和单矿物(磷灰石、独居石、长石、黄玉等)均存在稀土"四重效应"这一现象，本文研究提出，稀土"四重效应"是富挥发分过铝质岩浆体系的一个基本特征，其机制既不可能由含稀土的副矿物早期结晶引起残余熔体相中REE含量变化的结果，也不能定性地归因于流体相与熔体相相互作用过程中稀土元素在流体/熔体之间分异的结果，而很可能与伟晶岩岩浆形成之前某些过程密切相关，S型花岗岩岩浆在液相线以上存在硅酸盐熔体与高盐熔体的不混溶液相分离有可能是过铝质岩浆体系产生稀土"四重效应"的主要原因。

The result indicates the t-BHP or diamide both cause the mass loss about the membrane protein thiol in hepatocytes, the fast oxidization about glutathione in hepatocytes, the leakage of lactate dehydrodenase, but the level of t-BHP is larger than of diamide. In the aspect of lipid peroxidation, only the t-BHP produces apparent change. As to actin and tubulin, they both find fall-off and present time-dependency effects. The result in Confocal fluorescent microscope also show these two cytoskeletal proteins are related to cell blebbing, but they don''t play the same role during the porcess. Tubulin may be more important than actin. If the study predispose dithiothreitol before adding t-BHP or diamide, then the damage by the diamide is repressed, but just partly protection for the damage by t-BHP.

结果显示t-BHP或diamide均可造成细胞膜蛋白硫醇大量流失与胞内GSH快速氧化，亦显著导致乳酸去氢□渗漏，但t-BHP诱发的渗漏程度大於diamide；在脂质过氧化方面，则仅t-BHP处理组产生明显的脂质氧化情形；至於肌动蛋白与管蛋白单体均可见减少且呈现时间依赖效应；在雷射共轭焦萤光显微镜观察中，亦显现这两种架构蛋白与细胞膜起泡有关，但两者在小泡生成的过程中扮演的角色并不完成相同，可能管蛋白较肌动蛋白重要；如果细胞在t-BHP或diamide加入前预先以dithiothreitol处理，则diamide 所造成的伤害显著的受到抑制，但DTT对t-BHP所诱发的伤害则仅有部分保护效果。

The results show that the compound conductive fiber has typical structure of sheath-core consists of black greened polyaniline electric conductive deposition as the skin and the white polypropylene matrix fiber as the core, which makes the compound fiber preferable physical mechanical property. The intensity and the elongation ratio of the electric conductive fiber are decreased but the thermal stability is enhanced after modified. The compound fiber has the good acid resistance but poor base resistance. The thermal stability of the compound fiber prepared by 4-methyl-benzene sulfonic acid is better than that prepared by hydrochloride acid. Moreover, the compound fiber can be re-doped by other organic or inorganic acid after freed from the adsorbed acid. Furthermore, the electric conductivity of the compound fiber decreases with the temperature increasing but hardly changed with the humidity. The adsorptive ability and therefore the content of the polyaniline, the constant of electric conduction, and the durability of the compound fiber can be enhanced by thinning the diameter, section heteromorphosis, section heteromorphosis and plasma treatment of the surface or blending with COPET of the fiber.

结果表明：复合纤维是聚丙烯与聚苯胺的共混体系，具有典型的皮芯型结构，皮层为墨绿色的聚苯胺沉积层，形成连续的导电通道，芯层为白色的聚丙烯基质纤维，提供物理机械性能；导电改性后纤维的强度、强力和伸长率均有下降，但热稳定性得到提高；复合纤维的耐酸性比耐碱性好，以对甲苯磺酸做掺杂酸比盐酸掺杂聚苯胺热稳定性好，脱掺杂后的复合纤维，可用其它无机酸或有机酸进行再掺杂；复合导电纤维的电导率随温度升高降低幅度较大，但几乎不受湿度影响；基质纤维细旦化、截面异形化、表面等离子体处理或共混COPET等改性处理均能提高纤维的吸附性，进而提高复合纤维表面聚苯胺含量、电导率和耐久性。

Northern blot revealed that DAT is expressed weaklt but specificlly in the brain tissue, and in situ hybridization DAT is restrictedly expressed in the adult brain tissues including substantia nigra and striatum, suggesting an important function in the dopaminergic system.

利用cRNA探针的原位杂交组织化学研究，发现DRP在成年大鼠脑组织神经元和胶质细胞均有表达，以胶质细胞广泛表达是其重要特征；而DAT在成年脑组织仅限于少部分核团的有限表达，包括黑质和纹状体。

The spermatozoa are embeded in a extracellalar matrix composed of high dense fibrils matrix and flocculent and concentric vesicles similar to that in the primary spermatophore layer, but the later lack of spermotozoa. The flocculent and concentric vesicles are often seen to release their contents around the main body of spermatozoa. The spermatozoa may absorb the contents to form vesicular zone and membrane zone in sperm nucleu. The secondary spermatophore layer is distinctly subdivided into inner region and outer region. The loose outer region consists of canaliculated reticulum and large flocculent vesicles.

输精管内的精荚为管状，由精子群、精荚基质及初级精荚壁和次级精荚壁组成，初级精荚壁与精荚基质是相连续的，它们之间无明显界限，两者均由电子密度较高的纤丝状基质和絮状泡和同心圆泡组成，但后者不含精子，后者中的絮状泡和同心圆泡常在精子主体部周围释放内含物，可能与形成精子细胞核中的泡状带和膜状带有关，在交配后的雌虾，其头胸部腹面上粘着的精荚中，其基质内已不见絮状和同心圆泡，仅见稀疏的纤丝。

By electrospray ionization multistage mass spectrometry, the fragmentation pathways of ＋ and ＋ions of homocyclic peptides were studied in detail. The fragmentation pathways of ＋ ions were different from those of ＋ ions and their dissociation mechanisms were proposed, respectively.

采用电喷雾多级质谱技术，对系列均环多肽＋离子和＋离子的质谱裂解规律进行了系统研究，两种系列的离子具有不同的质谱裂解特征，分别提出了其可能的质谱裂解机制。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

objective to compare image manifestations values between high resolution computerized tomography and x-ray chest film in idiopathic interstitial pneumonia in the elderly.methods we analysed and compared image manifestations between hrct and x-ray chest film with 12 cases of clinically suspected iip in the elderly.results ct and hrct had more sensitivity and specificity than x-ray chest film.there were more image manifestations in hrct such as grand grass,net,line,nodular,honeycombing,bronchiectasis,honeycombing cyst,peribronchovascular interstitial thickening and irregularity.there were significant difference between them （p.05）.these patients who were suspected iip had better control and remission after being treated with hormone and immuno-suppressive drug.conclusion it have more significant virtues in hrct to manifest iip in the elderly than x-ray chest film,and it also may manifest iip curative effect.

目的 比较高分辨断层摄影术、x线胸片检查对老年特发性间质性肺炎的诊断价值。方法对12例临床疑诊为间质性肺炎的老年患者，进行胸部hrct与胸部平片检查，并对照分析。结果胸部ct在诊断方面比常规胸片有较大的优越性，hrct则有更高的敏感性和特异性，hrct表现出磨玻璃影、网状、线条、小结节、蜂窝影，支气管扩张、细支气管扩张、支气管壁和血管壁增厚及不规则等征象，12例临床疑诊为间质性肺炎的患者，经胸部hrct诊断的12例，而胸部平片诊断的仅有2例，二者比较差异有显著性（p.05），hrct疑诊的iip患者，经临床激素及免疫抑制剂治疗，病情均得到控制或缓解。结论 hrct表现老年间质性肺炎的特点明显高于胸部平片，且hrct可以反映间质性肺炎的疗效。

Results 1、 Generally, we can see the original blue and white, shiny, no cracks in the articular surface of the cartilage after the stress increases gradually yellow, surface roughness, cracks appear; when the pressure decreases, the yellowing, rough, the color of the fracture restore gradually and become shiny.2、the shiny smooth surface can be seen under a light microscope, formation, cell distribution, tidy, clear the level of cartilage at the articular surface stress increases, the surface roughness changes, defects, disordered cells, uneven dyeing ; when the articular surface of the pressure gradually decreased, the cartilage gradually repair and the surface of cells at the surface appear only disorder.3、immunohistochemical observation can be seen throughout the observation period, cartilage cells are type Ⅱ collagen expression and expression after 3 weeks gradually weakening, when the seventh week begin to strong gradually.4、 electron microscopy shows that when stress increases the articular surface, the cartilage cells became flat, the cytoplasm in the endoplasmic reticulum, Golgi apparatus decreased with collagen disorders; and when stress decreases the articular surface, cartilage cells gradually returned normal, cytoplasm in the endoplasmic reticulum, Golgi body gradually restore quantity; collagen fibers with a gradual rules.

结果：①大体观察可见到原本蓝白色、有光泽、无裂纹的软骨在关节面压力增大后，逐渐呈灰黄色，表面粗糙，出现裂隙；当压力逐渐减小后，变黄、粗糙、有裂隙的软骨颜色逐渐恢复，变得有光泽②光镜下可见表面光滑、平整，细胞分布均匀、整齐，层次清楚的软骨在关节面压力增大后，表面变粗糙、缺损，细胞排列紊乱、染色不均；当关节面压力逐渐减小后，软骨表面逐渐修复，细胞仅在表层排列紊乱③免疫组织化学观察可见整个观察期内软骨细胞胞浆内均有Ⅱ型胶原表达，术后3周内表达逐渐变弱，从第7周时开始逐渐变强。④电镜下可见当关节面压力增大后，软骨细胞逐渐变扁，胞质中内质网膜、高尔基体减少，胶原排列紊乱；当关节面压力减小，软骨细胞形态逐渐恢复正常，胞质中内质网膜、高尔基体数量逐渐恢复；胶原纤维排列逐渐有规则。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。