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Results: Neonatal rats in hypoxic-ischemicgroup behaved restlessness, cyanosis, deep and rapid breath, astasia, lethargy, irritation and spasm; There were local pyknosis, fragmentation, dissymmetry, blur or disappearance of nucleoli, raritas of ground substance in left cerebral cortex; but there was no statistic significance in chinese traditional medicine group and sham group. The expression of HIF-1α mRNA in brain tissue of experimental group and chinese traditional medicine group were higher than that in sham group, especially chinese traditional medicine group at 3d; HIF-1α positive cells were found in cerebral cortex and hippocampus. There were more HIF-1α positive cells in experimental group and chinese traditional medicine group and mainly in vascular endothelial cells.

结果 缺氧缺血后大鼠相继表现为烦躁不安、全身发给、呼吸加深加快、站立不稳、嗜睡、激惹或间断发作的痉挛和抽搐;HE染色显示实验组大鼠左侧大脑皮层出现局灶性神经元核固缩,核碎裂,核仁偏位,不清或消失,基质疏松;中药组大鼠脑组织结构基本接近假手术组,无明显水肿和坏死表现;实验组和中药组大鼠脑组织HIF-1α mRNA表达较假手术组明显增加,尤其是中药组实验第3日者;免疫组化显示实验组和中药组各时间点大鼠大脑皮层和海马区均可见不同程度的HIF-1α表达,明显高于假手术组,阳性表达主要在血管内皮细胞,海马和皮层的锥体细胞亦有HIF-1α阳性细胞分布。

Most endothelial cells fell off, elastic fibre autolyze; the number of SMC decreased, some SMC nucleus contracted completely or depressed, typical apoptosis body were seen in later stage, muscle silk autolyzed and disappeared mostly; in outer layer saw much collagenic fiber, arranged unorderly; inflammation cells were seen in the aneurysm wall(hypertrophy cell et al.).

多数瘤壁的内皮细胞溶解脱落,不连续,弹力纤维自溶;动脉瘤血管壁均可见SMC明显减少,较多SMC染色质边聚、固缩,部分SMC核全部固缩或出现不规则凹陷,SMC核胞浆或胞核部分出现脱落或裂解成碎片,晚期可见典型的凋亡小体出现,肌丝大都自溶消失:外膜可见大量的胶原纤维,排列较紊乱;瘤壁还可见炎性细胞浸润。

Result 1991, area of Lian Yun harbor produced half plait to knit grain snail 2003 toxic 11, 2004 Ningxia Yinchuan the snail when a; is toxic 1, toxicity test of acute of small white rat all check gives toxin of paralytic sex shellfish; color atlas of afore-mentioned photograph of fluid of classics of shellfish check appearance, mass spectra couplet gives balloonfish toxin TTX and its ramification with analytic check.

结果1991—2003年连云港地区发生半褶织纹螺中毒11起,2004年宁夏银川1起;时螺中毒1起,小白鼠急性毒性试验均检出麻痹性贝类毒素;上述贝类检样经液相色谱—质谱联用分析检出河豚毒素TTX及其衍生物。

This result indicates that WT1 gene plays an important role in differentiation and development of fetal kidney and may be the factor that promotes metanephric blastemal cell to differentiate into epithelial cell.

结果显示小胎龄肾组织中WT1蛋白在胚基细胞和幼稚肾小球细胞核表达而大胎龄组肾组织中WT1在肾小管细胞胞浆表达,阳性率分别为57.1%(8/14)和46.2%(6/13),提示WT1基因在胚胎肾分化发育的过程中起着重要作用,WT1蛋白可能是促进后肾胚基细胞向上皮细胞分化的调控因子,其表达在时间上和空间上都受到严格的调控,WT1的表达异常可能导致胚基细胞分化停滞。17例肾母细胞瘤WT1蛋白表达阳性率为41.2%(7/17),阳性部位在胚基型和上皮型肿瘤细胞核,表达部位和阳性率与早期胚胎肾相似,其中间质型肾母细胞瘤均为阴性,胚基型和上皮型肾母细胞瘤阳性率70%(7/10),两组间阳性率有显著差异。

Simulation results show significant vibration of the axial constraint force of the flexible links and the centroidal velocity of the central rigid body due to the increasing temperature.

数值仿真结果表明,当温度升高时,机械臂的轴向约束力和中心刚体的质心运动速度均出现显著振荡,而适当减小温度变化率,可以有效地控制振幅。

In invasive clostridial infections, spores reach tissue either by contamination of traumatized areas Or from the intestinal tract.

组织肿胀影响血液的供应。细菌所产生的引起坏死的毒素和透明质酸酶均有利于感染的扩散。

Result All of 4 cases were intracerebral hematoma and reactive cerebral collagenous hype-rplasia.

结果 均为脑内血肿,反应性脑胶质增生。

APE/Ref-1 expression was found mainly in cytoblast of gastric mucosa and metastatic lymph node.

APE在胃黏膜组织中普遍表达,胞质、胞核均有表达,以胞核表达为主。

Results ① The percentage of positive TPOAb and TGAb were 91.4% and 74.4%, respectively in all the AIT patients. 47.6% of the patients had TSH levels within normal range (0.3~5mu/L).② All of the slides had different grades of lymphocytic infiltration. 49.3% had germinal center, 32.8% had Askanazy cells, 26.9% had plasma cells, 22.4% had colloid, and 9% had multinuclear giant cells.③ Lymphocytic infiltration was divided into four degrees. The levels of TSH and TPOAb increased significantly in the extremely heavy lymphocytic infiltration grade than in the others (P.05). There was no relationship between serologic markers and other cytopathologic features.

结果 ①82例患者中TPOAb、TGAb的阳性率分别为91.4%和74.4%,约有半数(47.6%)TSH值位于正常值范围内(0.3~5mu/L);②所有患者细胞病理学均存在淋巴细胞不同程度的浸润,49.3%可见生发中心,32.8%可见嗜酸性变细胞,26.9%可见浆细胞,22.4%可见胶质,9%可见多核巨细胞;③将淋巴细胞浸润程度分级,分别与TSH、TPOAb及TGAb进行相关性分析,发现仅淋巴细胞极重度浸润者其血清TSH、TPOAb水平较其他组显著升高(P.05),其他细胞病理学改变与血清学指标之间未发现显著相关性。

Then histochemical, electron microscopic, enzyme histo cytochemical and confocal laser scanning microscopic methods were employed to study the distribution of vinculin, cathepsin Dand nematolysosomes ...

结果在正常对照组神经元,组织蛋白酶D与纽蛋白分布于胞质及突起内;在CD及PMA处理神经元,纽蛋白及组织蛋白酶D的分布呈向心性移动,但集聚的部位不同;电镜酶细胞化学方法显示CD组及PMA组神经元内线状溶酶体均增多。

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呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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