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Methods Fifteen rabbits were divided into three groups: group A (posterior limbs was completely cut off and posterior tibia artery was ligated with posterior tibia vein), group B (posterior limb was uncompletely cut off and posterior tibia artery was ligated with posterior tibia vein), group C posterior limb was completely cut off and traditional operation type was applied to ligate the posterior tibia artery with posterior tibia artery (control group.

用15只兔分3组:A组为完全离断小腿胫后动脉缝接胫后静脉组,B组为部分离断小腿胫后动脉缝接胫后静脉组,C组为完全离断小腿应用传统的胫后动脉缝接胫后动脉对照组,3组均结扎胫前动脉,保留胫前静脉等未动脉化的静脉及缝接其它离断软组织。

This implies that DNA methylation of promoter exon 1_7 may not underly the mechanism of GR up-regulation in GLP-1 -programmed rats.5 Hippocampal expression of GLP-1R and NGFI-A mRNAHippocampal GLP-1R (p =.009) and NGFI-A (p =.001) gene mRNA expression were significantly up-regulated in GP group as compared to VP group.Taken together, neonatal intramuscular injection of plasmid DNA encoding GLP-1 affects behavior and hippocampal GR expression in adolescent rats.

提示GR exon 1_7启动子区域DNA甲基化可能不参与GLP-1导致的GR转录上调。6海马GLP-1R和NGFI-A mRNA表达GP组大鼠GLP-lR(P=。009)和NGFI-A(P=。001)表达均显著高于VP组,表明肌肉注射GLP-1可能通过作用于其海马受体提高NGFI-A表达,进而调控GR表达。

Analyzing the model, especially the activity of Taihang Mountain piedmont fault, we got such main conclusion:1. Based on sequence stratigraphy, the strata is divided from the selected drills. And the Quaternary stratigraphic framework of Handan city is established, dividing the Quaternary strata into four parts- Qh, Qp3O , Qp2Y and Qp1G.2. With all the selected drill data of Handan city, a drill database is established. A quaternary strata 3D model of Handan city is imitated by GOCAD and ArcGIS, and so are the bottom structural map of each horizon.3. Analyzing the 3D model and the contradistinction section of drills, we got: the stratum of Qh and Qp3 is smooth and flat, with a feature of a higher west, little difference between south and north and undistinctness of faults; there are several depocenters along S-N and N-W in the stratum of Qp2, and the evolution of the stratum is controlled by a couple of ruptures, which means the tectonic movement is active in this period of time.4. Since quaternary, main tectonic movements happened in Qp2 and have been stable in Qp3 and Qh.

获得主要结论如下:1、利用层序地层学的方法将收集的邯郸市钻孔以及论文所依托项目野外施工的钻孔进行了具体的地层划分与对比,建立了邯郸市第四系等时地层格架,将邯郸市第四系划分为全新统、更新统上部欧庄组(Qp3O)、更新统中部杨柳青组(Qp2Y)和更新统下部固安组(Qp1G)。2、利用收集到的邯郸市水文、工勘钻孔以及所依托项目初勘和详勘两个阶段野外施工的钻孔数据,建立钻孔数据库,通过使用三维建模软件GOCAD和地理信息系统软件ArcGIS等进行模拟,得到邯郸市市区部分第四系地层三维可视化模型,并获得各个地层的底部构造图;3、通过对所天生模型和钻孔廊带对比剖面的分析,可以得到:全新世和更新世晚期(Qp3)时期地形整体较平缓,整体上显示西高东低、南北差异不大的格式,断裂显示不明显;更新世中期(Qp2)时期沿南北向和北西向存在几个沉积中心,地层发育受几条断裂的控制,反映了研究区的构造活动在更新世中期较为活跃;4、邯郸市自第四系以来,主要构造运动均发生于更新世中期,到更新世晚期及全新世时期逐渐趋于稳定,进而使更新统上部和全新统地层沉积均一且完好。

Chapter Six argues that the western preachers\' Euoropeanized vernacular versions of English Bible or Christian hymns played an unestimable part in late Qing dynasty\'s vernacular Chinese movement, the May 4~ vernacular Chinese movement and the May 4~ free verse movement by carding the diachronic change of Chinese literary language at the turn of 20~ century and looking into the relationship between the western preachers\' Chinese versions of English Bible or Christian hymns and the May 4~ vernacular Chinese, especially the free new verses written in the vernacular. The chapter concludes that the activities of remolding classical Chinese by the western preachers at the end of 19~ century are one of the sources of the May 4* new literature, one of the sources of the May 4~ new poetry in particular.

第六章通过梳理中国近代文学语言的历时流变,探究了十九世纪末西方传教士由于基督教圣诗和赞美诗的翻译而对汉语进行的改造活动与五四白话文运动,尤其是与白话新诗的关系,提出了西方传教士19世纪末开始的欧化白话翻译对晚清白话文运动、五四白话文运动以及五四新诗的历时嬗变均有着不可低估的影响和价值的观点,认为他们的翻译活动也是五四新文学,尤其是五四白话新诗的重要源头之一。

Mn(H_3biim)_2_2Cl_2 and Cd(H_3biim)_2_2Cl_2 have been synthesized from H_2biim, their structures were determined by X-ray crystallography. The two complexes have similar structures and both are neutral compounds. One N atom in H_2biim is protonated, forming a H3biim+ cation. The later is an unidentate ligand, the central metal, Cd or Mn is six coordinated and adopts a distorted octahedral environment.

合成了联咪唑锰配合物Mn(H_3biim)_2_2Cl_2和联咪唑镉配合物Cd(H_3biim)_2_2Cl_2,晶体结构表明这两个配合物结构相似,均为中性化合物,联咪唑的一个氮原子被质子化,形成一价阳离子(H_3biim~+),它采取单齿配位,中心Mn原子是六配位,其配位环境为畸变的八面体。

Besides, we found that the 5′ regions of Dnmt1 and Dnmt2 were nearly completely unmethylated in all normal adults, IVF fetuses, sperm and aborted clones.

此外,我们还发现在正常成体牛、体外受精胎儿、精子和克隆流产牛胎儿中, Dnmt1和 Dnmt2基因的5′端几乎均没有发生甲基化。

Results HPP1 gene was methylated in 37 of 52(71.2%) colorectal cancers and 12 of 21 (57.1%) adenomas cases. In contrast, HPP1 gene was unmethylated in all of the samples from healthy controls.

结果 结直肠癌粪便标本HPP1基因甲基化阳性率为71.2%(37/52),腺瘤粪便标本为57.1%(12/21),而正常粪便标本均为阴性。

Results ET-1 increased the synthesis of soluble type I collagen in different periods besides the 24h group, and had no effects on the type III collagen; immunohistochemical staining revealed that ET-1 also increased the synthesis of unsoluble type I collagen.

结果 ET-1较对照组除24小时时相外,均有不同程度的促HDPC可溶性I型胶原合成作用,但对III型胶原作用不明显;经免疫组化染色证实:ET-1尚可同时促进细胞非溶解性I型胶原合成。

Only weak expression of ICAM-1 was found on bronchial and alveolar epithelium, pulmonary arteriolar and venular endothelium in normal and sensitized rat lung. The expression of ICAM-1 in all tissues mentioned above were increased in asthmatic rats.

免疫组化结果显示,哮喘大鼠支气管上皮细胞、肺动静脉内皮细胞及肺泡上皮细胞ICAM-1表达均明显高于对照组。

The geology research of carbonate reservoirs in Ordovician of Tahe oilfield showed that many large dissolved vugs and fractures were developed. The spread of the reservoir take on a very heterogeneous state. And the typical fractured-vuggy reservoirs was formed. According to the combination of the various spaces, the formation was divided into vuggy formation, fractured-vuggy formation and fractured formation. The research showed that development of the vug is relevant to the its position on the structure, the fractures, the water surface and the weathering surface. Multi-phase charge and recharge of the oil in the reservoirs resulted in the complexity of the fluid distribution. So the"Bottle Model"was brought forward to explain the movement of the water-oil contact. The special storage space and the complex fluid distribution lead to the unstability of the production and the complexity of the water cut. In order to explain the characteristic of the fracture-vug unit was brought forward and the basic principle and method of the partition of the fracture-vug unit was formed. The classification and evaluation of the units were performed according the reserve and energy. Based on the research of geology characteristic and the fluid flow in the reservoir the comprehensive numerical simulation plan of the fractured-vuggy reservoirs were established. Through the selection of the simulation unit, fluid flow type and parameter equivalent the triple media reservoir simulation model was established. Considering the practical application the model was resolved by the DKR decomposition conjugate grads method. Based on the fine reservoir description of Dsitrict IV of the Tahe oilfield the various space type were classified and combined together. The geology model of Unit S48 was constructed. Two typical single well model was established according to the geology and the dynamic phenomena. Finally the single well model and the Unit S48 were simulated by the triple media reservoir simulator. Via the local grid refinement and coarsening in the simulation good matchs were gained. Based on the results of the simulation the reserve distribution, percent of reserve produced in various space and the natural energy were analyzed. The fluid was storaged in the fractures and vugs mostly and more than 90% the produced oil came from the systems. The energy belonged to the active one. The results of simulation accorded with the fact and showed the validity and practicability the research and the simulator.

塔河油田奥陶系碳酸盐岩油藏的地质研究表明,其储层中发育着很多大型的溶蚀洞、缝,储层的平面展布呈现出极度的非均质性,形成了典型的缝洞型碳酸盐岩油藏,根据各种孔隙介质在储层中的组合,将储层分为了溶洞型、裂缝-溶洞型和裂缝型三类;研究表明溶洞储层的发育和构造位置、裂缝的发育、潜水面和风化面的位置等因素有关;多期充注的油气成藏模式导致了流体复杂的赋存状态,由此提出了所谓的&瓶子模型&,解释生产过程中油水界面的变化;特殊的储集空间类型和流体分布特征导致油田在开发过程中表现出很大的不确定性和含水变化的复杂性,为了合理的解释油气田开发过程中的动态特征,提出了&缝洞单元&的概念,并制定了&缝洞单元&纵横向划分的基本原则和依据及划分方法,并对&缝洞单元&进行了分类和评价;基于地质特征和流体在其中流动规律的研究,提出了缝洞型碳酸盐岩油藏的数值模拟综合解决方案,通过模拟单元的选择、流动类型和参数的等效,建立了三重介质油藏三维三相数值模拟模型,采用不完全LU分解预处理共轭梯度法进行了求解;在塔河油田4区精细油藏描述的基础上,将各种类型的孔隙空间进行了归类组合,建立了S48单元的地质模型;通过对油井生产动态进行分析研究,建立了两类和油井地质、生产动态相对应的单井模型;最后应用三重介质油藏数值模拟软件对单井模型和S48单元进行了数值模拟,通过局部加密和粗化等技术模拟流体流动规律,取得了很好的拟合效果;结合数值模拟结果,分析了各种介质中的储量分布、储量产出的百分比以及地层的能量,认为塔河油田缝洞型油藏中流体绝大多数储集于缝洞系统之中,所产出流体90%以上也来自于缝洞系统,其底水能量属于较充足的类型;模拟结果和油田实际情况符合较好,说明了地质研究和油藏数值模拟研究的正确性。

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