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In order to clear heterogeneous reservoirs waterflooding performance, and decreased interlayer and within-layer contradictions, and improved the water flooding recovery, experimental study should be conducted first, This paper based on Pucheng Sasan reservoir sandstone cores to study object. Multi-point pressure measurement of water flooding oil experimental apparatus was established. Through the three-layer water flooding experiment to study injection strategy, interlayer interference and recovery factors. True sandstone micro-model water flooding used newly developed color visual image analysis system researched water-drive types, forms of residual oil and waterflood efficiency. Percolation mathematical model was established, black oil simulation program was developed, long-core displacement experimental results were matched, pressure and saturation change were researched by the simulation matching results.

为了明确非均质储层注水开发动态过程,减轻由于层间和层内非均质造成的开发矛盾,提高水驱采收率,本文从实验研究出发,以濮城沙三储层岩心为研究对象,建立了一套带多测压点的多层长岩心水驱油实验装置,通过开展三层水驱油实验,研究注水方式、层间干扰以及采收率影响因素;真实砂岩微观模型水驱油实验采用最新研制的彩色可视化图像分析系统研究水驱类型、残余油形成类型以及水驱油效率;建立并求解渗流数学模型,编制黑油模拟程序,对长岩心驱替实验进行拟合,通过拟合结果研究驱替过程中油水饱和度和压力的变化情况等研究工作。

Methods Constructed the model of fetal scarless wound healing and investigated the expression of collagen in fetal and adult rat wounds by immunohistochemistry and in situ hybridization.

染色,Ⅰ、Ⅲ型胶原免疫组化,Ⅰ、Ⅲ型胶原原位杂交。结果胎鼠伤口愈合快,组织结构再生完全,没有瘢痕形成,胶原呈网状正常排列,Ⅰ、Ⅲ型胶原蛋白及表达均增多,同时伴细胞数增多,Ⅲ型胶原首先形成网状排列;成年伤口胶原纤维沉积慢,平行排列的胶原逐渐呈束状填塞伤口以致瘢痕形成,伤口内Ⅰ、Ⅲ型前胶原mRNA表达均增多,细胞数目增多不明显。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

In peripheral blood,〓increases, so cause 〓 balance is broken, and 〓 which can induce inflammatory reaction increases obviously too; meanwhile, there are immuno- function change in the red cells, the RBC-〓 receptor rosette promoting rate of serum decrease, indicate this uveitic animal model have both cellular immunity dysfunction induced by T cells and the changes of RBC immuno-function. The analysis of the local and systemic immuno-function changes of uveitic animal model offers objective theoretical bases for combining the local treatment and the systemic treatment.

葡萄膜炎兔房水中房水中〓及IL-2均升高,病变葡萄膜组织中T细胞表面分化抗原的免疫组化检查显示大量阳性细胞,表明兔葡萄膜组织本身存在着免疫功能亢进所导致的病理改变,而外周血中〓增高,导致〓平衡失调,介导炎症反应的〓亦明显增高,同时伴有红细胞免疫功能改变,外周血中RBC-〓受体花环率及血清中RBC-〓受体花环促进率均降低,显示葡萄膜炎兔本身既存在T细胞介导的细胞免疫反应功能紊乱,也存在红细胞免疫功能改变,这种局部和全身的免疫功能改变分析为葡萄膜炎的治疗局部和全身相结合提供了客观的理论依据。

Bidentis were studied by adopting indoor bioassay. The results showed that the volatile matter of F. bidentis had not allelopathy to four receptor plants. The eluviated matter inhibited seedling growth of cotton obviously, the inhibition ratio of root and stem were 6.29% and 10.42% respectively. The aqueous extract of litterfall and root exudates had different inhibition to four receptor plants, The synthesis effectof all treatments was significantly greater than eluviated matter treatment except for B3 of the aqueous extract of root exudates, such as the synthesis effect of all treatments (A1, A2, A3, B1, B2, B3 and eluviation) were 44.74, 29.37, 14.5, 31.54, 16.52, 3.55, 1.48 respectively.

结果显示:黄顶菊自然挥发物对受体植物不表现化感作用;黄顶菊淋溶物对棉花幼苗生长表现出明显的抑制作用,对棉花幼苗高度和根长的抑制率分别为6.29%和10.42%;黄顶菊枯落物浸提液和根系分泌物浸提液对4种受体植物均表现出不同程度的抑制作用,除了黄顶菊根系分泌物浸提液 B3处理外,其它处理的综合效应均显著大于淋溶物处理,如黄顶菊枯落物浸提液( A1、 A2、 A3)、根系分泌物浸提液( B1、 B2、 B3)以及淋溶物等各处理对受体植物的综合效应分别为44.74、29.37、14.5、31.54、16.52、3.55、1.48。

The range of Mw values of amylose from different types of rice starch is from 3.29×105~2.75×106. There are no significant differences in the molecular weight distribution, Mw and RMS of the amylose leaches out at the temperature between the onset pasting temperature and 90℃.

研究表明,90℃以上高温不利于用浸出法从直链淀粉含量低的大米淀粉中分离直链淀粉,当温度低于90℃而高于糊化温度时,各个温度下均可用浸出法分离出直链淀粉,得到的直链淀粉具有十分相似的分子量分布、重均分子量和分子旋转半径。

The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups(P<0.01).The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group(P<0.01,P<0.05).The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面,差异均有显著性(P<0.01);IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性(P<0.01); MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达,差异具有显著性(P<0.01,P<0.05),MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达;TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

A systematic study on S and/or Pb isotopic compositions of the copper-bearing porphyries, ore minerals and andesite of the deposit shows that S isotopic compositions of ore minerals are similar to those of porphyries.

矿石矿物(208Pb/204Pb=37.917~38.230,平均值38.075;207Pb/204Pb=15.528~15.614,平均值15.571;206Pb/204Pb=17.929~18.082,平均值17.981)与矿化斑岩(208Pb/204Pb=37.832、37.883,207Pb/204Pb=15.529、15.538,206Pb/204Pb=17.906、17.910)以及安山岩(208Pb/204Pb=37.816~37.884,207Pb/204Pb=15.549~15.562,206Pb/204Pb=17.845~17.919)的初始铅组成基本一致,变化范围较小,表明三者具有相同的来源;在铅构造模式图上,所有样品铅同位素均位于造山带演化线上或附近,在铅同位素源区判别图中,均落入造山带和下地壳区域,这表明Pb主要来源于壳幔混合。

Results show that microbial biomass carbon and microbial biomass nitrogen in fertilized soil peak in the first several days, and then decline. Incubating both sweet maize straw and white clover have the highest yield, maxima of 529.57 mgkg^(-1) and 75.50 mgkg^(-1) respectively. They also release respired CO2 the most among all treated soils. The best mineral nitrogen release is in white clover incubating, with a maximum of 29.81 mgkg^(-1) under a 26-day culture, and then keeping 1.60 times the control and reaching 2.48 times at 80-day culture. Sweet maize incubating has the least mineral nitrogen release. It is 13%~53% of the control under a 26-day culture, with a maximum of 7.51 mg kg^(-1). Soil nitrogen mineralization is insignificant under sweet maize incubating with urea in short-term.

研究发现,各施肥处理的土壤微生物量碳、微生物量氮均在培养前期出现峰值,后期平稳降低;甜玉米桔秆和白三叶草绿肥同时还田的土壤微生物量碳、微生物量氮在各培养时期均最大,峰值分别达529.57 mgkg^(-1),和75.50 mgkg^(-1),土壤呼吸产生的CO2最多;白三叶草绿肥单独还田有利于土壤无机氮的释放,培养第26d无机氮达到最大值,为29.81 mgkg^(-1),之后一直在对照处理的1.60倍以上,第80d达到2.48倍;甜玉米秸秆单独还田不利于土壤无机氮的释放,培养的第26d至结束,甜玉米秸秆处理的无机氮为对照的13%~53%,最大为751 mgkg^(-1);甜玉米秸秆配施尿素,短期内不利于土壤无机氮矿化。

Results show that microbial biomass carbon and microbial biomass nitrogen in fertilized soil peak in the first several days, and then decline. Intercropping Incubating both sweet maize straw and white clover have the highest yield, maxima of 529.57 mg·kg-1 and 75.50 mg·kg-1 respectively. They also release the most respired CO2 the most among all treated soils. The best mineral nitrogen release is in white clover intercroppingincubating, with a maximum of 29.81 mg·kg-1 under a 26-day culture, and then keeping 1.60 times the control and reaching 2.48 times at 80-day culture. Sweet maize incubatingintercropping has the least mineral nitrogen release. It is 13%~53% of the control under a 26-day culture, with a maximum of 7.51 mg·kg-1. Soil nitrogen mineralizatiomineralization is insignificant under sweet maize incubatingintercropping with urea in short-term.

研究发现,各施肥处理的土壤微生物量碳、微生物量氮均在培养前期出现峰值,后期平稳降低;甜玉米秸秆和白三叶草绿肥同时还田的土壤微生物量碳、微生物量氮在各培养时期均最大,峰值分别达529.57 mg·kg-1和75.50 mg·kg-1,土壤呼吸产生的CO2最多;白三叶草绿肥单独还田有利于土壤无机氮的释放,培养第26 d 无机氮达到最大值,为29.81 mg·kg-1,之后一直在对照处理的1.60倍以上,第80 d达到2.48倍;甜玉米秸秆单独还田不利于土壤无机氮的释放,培养的第26 d至结束,甜玉米秸秆处理的无机氮为对照的13%~53%,最大为7.51 mg·kg-1;甜玉米秸秆配施尿素,短期内不利于土壤无机氮矿化。

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