在改变

A modern urbanization should be shown by the change in urban physical space and extensional formation, by the adjustment and the change in the urban internal social structure, by the govern structure which could fit in with the needs of the change of the social structure and the urban development.

城市化应该是现代化的，既表现在城市的物理空间和外延形态上的改变，也反映在城市内部的社会结构的调整和改变上，反映在适应社会结构变化和现代城市发展需要的治理结构上。

Right hemisphere became obviously swelling and pale, the sign ofhemorrhage under cerebral pia mater is manifest, and the other side of the brain isnormal. The colors of whole brains were stained into rose pink with TTC.

电镜超微结构形态学观察：小脑皮质最先在HIBD 1h出现凋亡征象，其次为大脑皮质在HIBD 12h、海马CA1区在HIBD 24h出现凋亡细胞超微结构明显改变，随损伤时程进展各部位细胞超微结构改变明显，细胞器损伤加重。

In many ways, reclassification may be compared to changing colors on a map , in that the reclassified attributes may plot out in new colors.

在钗h方法中，重新分类常被比喻成在地图上改变颜色，而重新分类后的属性就像在地图上的改变后的新颜色。

Results Analysis of the expression of proteins of JAK2 in leukemic blasts, there was no detectable constitutive expression of phosphorylated JAK2 in all the AML samples analyzed; Furthermore, we could detect a constitutive activation of STAT 3 by immunoprecipitation of the targeted protein in primary leukemic blasts from 3 of 11 AML patients without any cytokine treatment; Pretreatment clinical characteristics, and treatment regimens did not differ significantly between patients with and without constitutive STAT3 activity, there was not significant relation between the constitutive activation of STAT3 and the FAB subvariety and chromosome karyotype; However, the 3 patients with constitutive STAT3 activity seemed to have adverse treatment outcome, one did not show remission, the other two patients relapsed shortly after remission; Consistent with the above-mentioned result, leukemic blasts from the 3 samples with constitutive expression of STAT3 showed higher percentage of spontaneous apoptosis and S-phase cells.

在实验研究基础上，本研究进一步运用免疫沉淀和Western Blot印迹方法，检测AML患者原代细胞JAK2和STAT3活化情况，并分析了STAT3活化与AML患者预后有关指标改变的关系。结果我们的初步研究发现，11例AML患者中，有3例呈现STAT3组成型活化（STAT3阳性，下同），无一例呈JAK2组成型活化。上述3例STAT3组成型活化与FAB分型和染色体核型改变未见明显相关性；在此3例患者中，1例未取得缓解，另外2例虽然取得短暂缓解，但均在二个月内复发。上述3例STAT3阳性AML患者S期白血病细胞百分率数值较组高，而凋亡率数值较低。

Experimental process, to determine the most suitable reaction temperature, the temperature in the most appropriate amount of catalyst to change and to identify the most suitable amount of catalyst, in the amount of catalyst and temperature conditions to determine the types of changes in solvent, and to compare the differences reflect under the conditions of the conversion rate of dimethyl sulfoxide.

实验过程中，先确定最适合的反应温度，在最合适的温度下改变催化剂的用量并确定最合适的催化剂用量，在催化剂的用量和温度确定的条件下改变溶剂的种类，并比较在不同反映条件下的二甲基亚砜的转化率。

I have been wandered through Internet at early time, from curiosity to habit and even in the shape of dependence, I am always looking for something, the life of thinking and feeling have changed via time flows, my heart has never changed except for only way to pursue a dream---------that is to settle a home for my soul, just let my feeling and thinking could leap over myself through unconstraint, I don't want myself indulge in trivial matters and wear away my initial passion and love with life, so I would like to cherish every moment in life.

很早的时候就游离在互联网中，从新奇变成习惯，甚至一种依赖，一直在寻找着什么，生活的所思所悟都随着时间的变化而改变，唯独那寻梦的心没有改变——那就是给自己的心灵安一个家，让自己的思绪可以天马行空的跨越自我，不再让自己沉浸在生活的琐碎中磨灭掉那对生命最初的激情和热爱，从而珍惜生命中的每一刻。

But Robert Sweet, the presiding judge, disagreed, at least as far as the BRCA genes are concerned. After weighing up Myriad's arguments, he ruled:"It is concluded that DNA's existence in an 'isolated' form alters neither this fundamental quality of DNA as it exists in the body nor the information it encodes. Therefore, the patents at issues directed to 'isolated DNA' containing sequences found in nature are unsustainable as a matter of law and are deemed unpatentable subject matter."

但首席法官Robert Sweet的答案却是"否"，至少是在考虑BRCA基因一案后给出了这个答案，仔细掂量了Myraid公司的陈词后，他裁定说"我们得出结论：DNA结构是'脱离个体'的存在物，它既不能在人体内改变其基本特征，也不能改变它所编码的信息，因此，这个正在审议中的专利所指的"脱离个体，独立的DNA"，它包含序列信息，是在大自然中所发现的，把它当作一个法律问题来看是不成立的，应当作为一个不可申请专利的条目"。

Results 6 patients with PAP presented with ground-glass opacification of the bilateral lungs on HRCT. Typical chest HRCT scan showed "map-like" lesions in 3 cases and "cobble stone-like" lesions in 3 cases. Multifocal consolidative opacities in the lungs were seen on HRCT in 3 cases. Lung biopsies from 6 patients with PAP revealed a prominent positive periodic acid-Schiff intra-alveolar exudates. There were normal alveolar spetasis in 3 patients while interstitial thickening, fibroblast hyperplasia, interstitial fibrosis in the others.

结果 6例患者在不同层面可见磨玻璃影，其中2例可见小结节影；3例表现为两肺斑片状磨玻璃影与周围肺组织分界清楚，呈地图样改变；3例因磨玻璃影与小叶间隔增厚交织成铺路石样改变；3例可见肺泡实变融合成密度较高的斑片状阴影，1例在肺泡实变区可见&空气支气管征&。6例患者活检肺组织在光镜下显示肺泡腔内充满大量块状或颗粒状嗜伊红物质，PAS染色阳性，AB染色阴性，其中3例肺泡间隔正常，3例肺泡间隔增宽，可见慢性炎性细胞浸润、成纤维细胞增生和胶原沉积。

The advanced expression of Filaggrin may start the mechanism of apoptosis ahead of tune and the premature expression of TGK may accelerate the formation of cornified cell membrane,which will speed up the terminal differentiation of keratinocytes.Consequently,the hyperproliferative keratinocytes differentiate and exfoliate.

K17在扁平庆皮损中染色为阴性，而在寻常庆、尖锐湿虎皮损中为阳性，这提示：扁平庆的异常增生比寻常庆、尖锐湿庆要弱，这与扁平庆的临床表现和病理改变相一致；K17与炎尖锐湿疣初期表现症的发生有关，在三种庆的病理改变中，扁平庆的炎症现象最微弱，这与K17的染色阴性相吻合。

Based on an analysis of distribution pattern of hydrocyclone"s axial velocity, by changing the inlet flow rate Qi and split ratio Fand making an investigation in the effect of Qi and F on axial velocity field, the factors causing the forming of short-cut circuit and circulating flow are found. It is considered that the short-cut circuit and circulating flow are produced by the structure of the hydrocyclone, and can"t be eliminated completely, though they interfere the flow field inside a hydrocyclone and affect the separation accuracy. Test results show that, by increasing Qi and F and controlling them in a certain range, the separation efficiency of the hydrocyclone can be improved.

在研究旋流器轴向速度分布规律的基础上，分析了短路流与循环流的形成原因，试验研究了改变操作参数，即改变入口流量Qi与分流比F对轴向速度场的影响认为短路流与循环流是由旋流器结构决定的，很难完全消除，它们干扰了旋流腔和大锥段的流场，在一定程度上也影响了分离精度试验结果表明，加大入口流量Qi与分流比F，并将其控制在一定范围内，便可提高分离效率这项研究对水力旋流器分离机理的认识与实际应用均有重要意义

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。