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Abstract] AIM:To investigate the role of nuclear factor κB in the induction of iNOS gene by TNFα and LPS in endothelial cells and the effect of antioxidant on the induction of iNOS. METHODS:Nitrite was determined based on Griess reaction. iNOS mRNA was analyzed using Northern blot. NFκB in the cell nucleole was detected with electrophoretic mobility shift assay.RESULTS:(1)NO production and iNOS mRNA expression induced by LPS and TNFα was blocked by pyrrolidine dithiocarbamate or N-acetylcysteine.

研究表明内皮细胞激活时iNOS表达的调控主要发生在转录水平。iNOS基因的启动子区域含有多个转录因子的结合位点包括NFκB、AP-1、NF-IL6,Oct-1等[2],而核因子κB(nuclear factor κB, NFκB)被认为在多种参与炎症反应的蛋白质因子的基因调控中担任重要角色,因而可能是内皮细胞激活的调控中一个重要转录激活因子[2,3]。

A fuzzy logic controller based on Genetic Algorithm has been devised aimed at this point. GA is employed to optimize the membership functions of the Fuzzy Logic Controller and the initial values of the quantifying factors and the scaling factor. And the quantifying factors and the scaling factor are adjusted on-line according to the output of the fuzzy control query table.

针对这一特点,本文设计了一种基于遗传算法的模糊控制器,利用遗传算法来优化模糊控制器的隶属函数及量化因子和比例因子的初值,并且根据模糊控制查询表的输出来在线调整量化因子和比例因子

Results:According STAI, the scores of anxiety state factor,negative anxiety state factor, trait anxiety state factor, negative trait anxiety state factor and the total scores of unstable angina patients' were all higher than those in the control group.

结果:STAI评分比较中,不稳定型心绞痛患者的状态焦虑因子、负性状态焦虑因子、特质焦虑因子、负性特质焦虑因子和STAI总分均分都明显高于对照组

The orthogonal design of fifteen factors and two levels is made. At the same time, fifteen components are tested and five key factors have been selected out .Finally the second orthogonal design of five factors and four levels is carried on and the new optimum component of artificial diet of rice stem borer is reached.

同时,本文从已报道的不同二化螟人工饲料中选择了15种饲料成分,采用15因子2水平的正交试验设计,对这15种成分进行了优化,并从中筛选出5个关键因子,然后对这5个关键因子进行了5因子4水平的第二次正交试验优化设计,得出了二化螟人工饲料新的优化配方。

Experiment shows that both the dry plate pressure drop and the wet plate pressure drop increase with the increase of the kinetic energy factor in plate hole but have no influence of the height of cap. The wet plate pressure drop linearly ascends as the clear liquid height increases. Liquid lift-up increases at first then decreases with the increasing of the kinetic energy factor in plate hole, increases with the clear liquid height increasing and the height of cap decreasing, but as the kinetic energy factor in plate hole increased, the influence of height of cap will gradually decreased.

实验表明干板压降、湿板压降均随板孔动能因子的增大而增大,不受罩体高度变化的影响,湿板压降随清液层高度的增大而增大,成正比关系;液体提升量随板孔动能因子的增大先增大后减小,随清液层高度的增大而增大,随罩体高度的增大而减小,但随板孔动能因子的增加,罩体高度的影响逐渐变小;漏液量随板孔动能因子的增大迅速减小,随清液层高度的增大而增大,但接近漏液点时清液层高度的影响不明显。

Results The score of openness of sexual thought was 3.38±0.71, diversity of sexual behavior was 2.83±1.06, acceptant of sex trade was 2.16±0.61, alterative of sex objects was 1.89±0.65 and abundance of sexual knowledge was 3.11±0.75; Male's scores were ...

结果被试总体性观念各因子的得分在1.89±0.65~3.38±0.71之间,即性思想开放性、性行为多样性、性交易接受性、性对象可选性和性知识丰富性;上述因子的得分,男生显著高于女生;四年级显著高于一、二、三年级;城市生源学生显著高于农村生源学生;性观念因子高分组与低分组的被试在心理健康因子上的敌对和偏执上差异显著,前者得分高于后者。

AF297709 , which has specific interaction with the promoter region of hTERT, was first screened out of the HeLa cells cDNA library with the method of yeast one-hybrid assary in 2000.It was found that TRAP has positive activation effect on the transcription starting of hTERT.

人端粒酶催化亚单位hTERT组分的水平决定了细胞中端粒酶的活性;hTERT表达是端粒酶激活的关键步骤,一些转录因子、肿瘤抑制因子、细胞周期抑制因子、细胞寿命决定因子、激素受体和病毒蛋白参与了hTERT表达调控。

Nerve stem cell can be differentiation into astroblast, oligodendrocyte and nerve cell induced by factors.

神经干细胞的增殖分化可受各种因素的影响,目前已知,许多细胞因子,生长因子,营养因子以及细胞外环境等因素的作用,可诱导神经干细胞向不同的终末细胞分化,若能在体外分离培养神经干细胞并在促分化因子的作用下,诱导神经干细胞向某一特定方向分化,将为干细胞的分化机制提供有力的实验依据。

MSCs capsulated in alginate microspheres were induced by TGF-β3 and IGF-I, serving as the experiment group. While those cultured without TGF-β3 and IGF-I were taken as controls.

实验组用转化生长因子β3和胰岛素样生长因子Ⅰ联合定向诱导藻酸钠微球包被的骨髓间充质干细胞3周,对照组培养条件中无转化生长因子β3和胰岛素样生长因子Ⅰ。

Tissue factor, a receptor on the cell surface of factor VII as well as a coactive factor to activate factor VII, plays an essential role in hemostasis through the activation of the intrinsic and extrinsic coagulation pathways simultaneously.

组织因子(Tissue factor,TF)既是Ⅶ因子在细胞表面的受体,又是激活Ⅶ因子的辅助因子,它可同时启动内外两条凝血途径,在生理性止血中起重要作用。

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推荐网络例句

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。