因子

We examined 2 representative growth factors: brain-derived neurotrophic factor and vascular endothelial growth factor.

检测两种典型的生长因子：脑源性神经营养因子和血管内皮生长因子。

The research applied landscape ecology, integrating land using, ecology networks, and the concept of human needed environment model addressed by Odum to build natural and cultural criteria which are used to decide natural factorsand cultural factors. Subsequently, applying the criteria and planning procedures to category land into agricultural and non-agricultural areas. The agriculture areas include basic grain production areas, and leisure agriculture areas. The non- agriculture areas include agriculture of river corridor ecology restoration areas and remnant cultivates lands. Above all, remnant cultivated lands are separated into wilderness, parks or indefinite areas because of different context.

本研究运用之理念包括地景生态学、整合土地使用、生态网络及Odum提出四种人类需求环境模型；据以研拟自然及人文面原则，进行自然因子(NDVI值、坡度、高度、土壤等)及人文因子之准则建构；再依准则及划设流程规划出农业及非农业区域二类型，其中农业类型包括基础粮食生产区、休闲农业区，非农业区包括河廊农业生态复育区及剩余耕地，其中剩余耕地又依背景因子不同划设为荒野化、公园化或模糊区使用。

They are already being evaluated in clinical trials as potential therapeutic agents for major human neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and motor neuron disease. However, delivery of polypeptide growth factors to compromised neurons in the CNS is problematic because their plasmatic half-life are very short and their abilities to cross the blood-brain barrier are theoretically null.

然而由于中枢神经系统中存在血脑屏障，神经营养因子类物质难以通过血脑屏障而到达靶部位；同时又因为神经营养因子在体内生物半衰期较短，使得全身性用药效果不够理想，另外还往往产生意想不到的副作用，如何解决这些问题对于深入研究神经营养因子在神经损伤及神经系统退行性疾病中的作用及开展临床应用前景研究有着十分重要的意义。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Customer segmentation is a critical step to the success of target or segment marketing. The effectiveness of customer segmentation depends on a good number of variables such as customers' demographic, behavioral, geographic, and psychographic characteristics. However, the huge combinations and correlations among variables make customer segmentation a challenging task, even with the aids of information technologies. The industry is desperate for effectual and powerful tool for excavating customer knowledge from the large accumulated data in the corporate database management system.

摘要顾客分群对於目标行销或市场切割的成功与否都是一个重要的关键步骤，顾客分群结果的优劣取决於其所采用的分群因子，顾客分群中常使用的分群因子有顾客的人口统计资讯、行为特徵、地理性资讯与心理方面的特徵等，然而，这大量与因子复合交错的资讯使得顾客分群成为企业的一个挑战，并且渴望寻求一个能够从大量累积的资料库系统中挖掘知识的工具。

Results the scoresof obsessive-com pulsive, interpersonal sensitivity, depression, anxiety, hostility, paranoid ide ation, general symptomatic index and number of positive items were significantlyhigher than those of the domestic norm.the multiple linear stepwise regression revealed that the nervousness of epq; fa ther's refusal, rejection; father's warmth and understanding; feeling of oppress ion and cognition of future object entered regression equation.

进入回归方程的变量有epq的n因子、embu的父亲拒绝否认因子和父亲情感温暖理解因子、压抑感及对未来目标的认识。

The results indicate that the presence of GSH increased the expression of exoY、exoS、phzA1 and gacA,while no difference was observed with others virulence factor genes tested.PAO1 produced markedly less pyocyanin than the wild type strain PAOIP＜0.01Treating with GSH, the PCN production of PAOI(△gshB was increased from 0.47μg/mL to 1.73μg/mL (P＜0.01),the PCN production of PAO1 increased from 1.3μg/mL to 1.9μg/mL(P＜0.05),this result indicates that GSH upregulates PCN production.

结果发现，GSH对启动子库中exoS、exoY、phzA1和gacA等致病性因子的表达有促进作用，对其余测试过的致病性因子则没有明显影响；铜绿假单胞菌分泌的重要致病因子绿脓菌素(pyocyanin，PCN)的含量，在PAO1中远低于PAO1P＜0.01加入GSH后，PCN平均含量在PAO1(△gshB中从0.47μg/mL提高到1.73μg/mL，差异十分显著(P＜0.01)，在PAO1中从1.3μg/mL提高到1.9μg/mL，差异显著(P＜0.05)，表明GSH对铜绿假单胞菌生产PCN有促进作用。

All the offspring will be Ay/at alright, but because the male had a pattern of rufous polygenes that determined his tan points should be medium toned and the female the same medium toned Gold; the offspring could be anything from Red (having randomly received lots of red checkers from both parents) to Cream (having randomly received lots of white checkers from both parents).

是也不是。所有后代的基因型都是Ay/at是对的，但因为公獒还有一组&修改基因&即红褐色因子群决定他的金色适中，母獒也一样有着适中的金色；因此他们的后代可能从奶酪色（从父母得到了较多的白色因子）到红色（从父母得到了较多的红色因子）都有。

Immunohistolochemical stain by monoclonal antibodies for growth factors and actin was used to detect whether there are abnormal expressions in saccular aneurysms.

利用血小板源性生长因子、转化生长因子（TGF-β1）、血管内皮细胞生长因子和肌动蛋白的单克隆抗体进行免疫组织化学染色。

The identification of protein were performed by searching the mass spectrometry data from the NCBInr database using the software of Sequest Bioworks3. 2. The results indicated that over 25 protein components including acid and basis phospholipase A2, nerve growth factor, presynaptic neurotoxin, hemorrhagic factor, thrombin-like enzyme, serine protease, glycogen synthase, metalloproteinase, maturase, L-amino acid oxidase, plasminogen activator, adhesion, cysteine-rich secretory protein, disintegrin, fibronectin-binding protein, fibrinogen clotting inhibitor A chain, vascular apoptosis-inducing protein 1, pyranose 2-oxidase, carbamoyl-phosphate synthase, as well as the homology proteins of snake venom ablomin, ablomin, catrin, mucrofirase, pallabin, salmosin and triflin homologues were identified from the GSSV.

从GSSV中鉴定出超过25种蛋白组分，主要包括：酸性磷脂酶A1、碱性磷脂酶A2、神经生长因子、突触前神经毒素、出血因子、类凝血酶、丝氨酸蛋白酶、糖原合酶、金属蛋白酶、成熟酶、L-氨基酸氧化酶、纤溶酶源激活物、外源凝集素、富含半胱氨酸分泌酶、去整合素、纤连蛋白结合蛋白、纤维蛋白原凝固抑制因子A、血管凋亡诱导蛋白1、氨甲酰基磷酸合成酶、吡喃糖－2-氧化酶以及ablomin， catrin， mucrofirase， pallabin， salmosin和triflin的同源蛋白。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。