因子

Objective To approach the expressions of vascular endothelial growth factor and transforming growth factor-beta in periosteum in patients with congenital pseudarthrosis of tibia and elucidate the pathogenesis possibility.

目的：明确血管内皮生长因子和转化生长因子-β在先天性胫骨假关节患者病变处骨膜组织中的含量，探讨其在发病机制中的作用。

Methods Fibroblastic stromal cells were isolated from fresh pseudomembrane from 7 patients undergoing revision arthroplasty for aseptic loosening of the hip and cultured in the presence and absence of bone cement (PMMA+BaSO4) particles.

酶消化法从人工假体周围假膜标本中分离FBSCs并作体外培养并加入骨水泥颗粒，检测FBSCs核因子kB受体激动剂配体和肿瘤坏死因子mRNA表达的变化。

Objective To study the mechanism in which the personality, copying style influenced survival time by changing immunity function in the patients with gastric cancer Methods The Minnesota Multiphase Personality Inventory, coping style questionnaires and immunity function were measured in patients with gastric cancer on late stage, gastric cancer patients with longer survival time, and normal control Results Psychopathic deviate, social introversion subscale scores of MMPI in groupⅡ were significantly lower than that in the other two groups ( P 05) Statistical difference were found between groupⅠand groupⅡ in problem saving factor and help seeking factor of CSQ ( P 05) Natural killer cell level in groupⅡ was significantly higher than in groupⅠ( P 05) There was negative correlation between the NKC and depression, psychopathic deviate, paranoia, psychasthenia, schizophrenia subscale scores of MMPI, there was positive correlation between NKC and SP, coping type in patients with gastric cancer Conclusion The gastric cancer patients with longer survival time are more extroversive and have more mature coping styles Their NKC level is relatively higher The results may be advantageous to improve the prognosis of gastric cancer

作者中文名：王健；邹义壮；唐丽丽；李杰；张东；金山；刘娟摘要：目的研究胃癌患者的生存期与个性特征、应付方式等心理因素，以及免疫功能的关系。方法对胃癌晚期患者、胃癌较长生存期患者及正常健康人分别进行明尼苏达多相个性测验、应对方式问卷、免疫功能测试，并做相关分析。结果(1)MMPI：胃癌Ⅱ组人格障碍评分(42.0±10.5)及社会内向评分(42.2±11.6)，低于其他两组[胃癌Ⅰ组为(49.3±11.2)分和(48.3±9.4)分，对照组为(48.6±10.9)分和(39.9±11.5)分；P均＜0.05]；(2)CSQ：解决问题和求助因子分，胃癌Ⅰ组[分别为(0.68±0.27)分和(0.42±0.18)分]均低于胃癌Ⅱ组[分别为(0.82±0.18)分和(0.65±0.21)分；P＜0.05和P＜0.01]，胃癌Ⅱ组更多采取成熟的应对方式；(3)自然杀伤细胞：胃癌Ⅱ组水平(21.4±9.2)高于胃癌Ⅰ组[(14.2±8.8)；P＜0.05]；而NK细胞水平与MMPI的抑郁(r=-0.35)、人格障碍(r=-0.39)、偏执(r=-0.29)、精神衰弱(r=-0.30)及精神分裂(r=-0.30)等量表呈负相关，与CSQ的解决问题因子(r=0.35)及应付方式类型(r=0.34)呈正相关。结论与胃癌Ⅰ组比较，胃癌Ⅱ组更为外向，负性情绪较少，更多采取成熟的应对方式，其NK细胞水平较高，对胃癌的预后产生了积极的影响。

The influence of drying parameters of freeze-drying on quality of pteridium aquilinum drying was investigated, and the impact of drying board temperature, drying chamber pressure and material thickness on Vc content was studied by nonlinear regressional orthogonal design.

考察干燥因子对真空冷冻干燥蕨菜品质的影响，用二次正交旋转组合设计的试验方法，分析搁板加热温度、干燥室压力和物料层厚度对蕨菜Vc含量的影响规律，建立了冻干因子与Vc含量的回归模型。

Methods Pterygial samples were extracted and collected and the pterygial endothelial cells and pterygial fibroblasts were cultured alone, conditional and co-cultured to form different culture systems. The methods included that to select the suitable intensity of ultraviolet by MIT, to detect the changes of curves of growth about two kinds of cells by MIT and to explore the developments of protein and RNA of vascular endothelial growth factor and fibroblast growth factor-basic in three culture systems under ultraviolet whose intensity is 20 mJ/cm^2 by ELISA and RT-PCR.

收集翼状胬肉标本，采用血管内皮细胞和成纤维细胞单独培养、条件培养和共同培养的方法构建体系，用MTT法选择紫外线照射细胞的适宜强度；采用MTT法绘制强度20mJ/平方公分紫外线照射下细胞生长曲线；采用ELISA和RT-PCR检测紫外线照射下3种体系中细胞上清液和细胞中血管内皮细胞生长因子和成纤维细胞生长因子的蛋白和RNA含量变化。

Objective:To investigate the pattern IGF-Ⅰ and IGFBP-3 concentrations in girl with ICCP at different pubertal.

目的 ：研究特发性中枢性性早熟女孩青春各期血清胰岛素样生长因子-Ⅰ和胰岛素生长因子结合蛋白3 (IGFBP3 )的变化规律。

We have researched distribution of TGF β and its receptor in various age group and discs of various degeneration grade, found that positive ratio of TGF β and its receptor is higher in below 40 year old group and discs of MRI Ⅰ and Ⅱ grade, mainly occur in fibrous cartilagous cells of fibrous annulus and nucleus pulpous; In group of 40-60 years old and grade Ⅱ and Ⅲ discs, TGF β decreased and TGF β R decreased not as much as TGF β; In above 60 years old group, TGF β and its receptor almost disappear.

生长因子包括TGF-β对细胞功能有重要调节作用，它是一种相对分子质量为2.5×10〓的二聚体多肽，几乎参与了哺乳动物所有细胞的病理，生理过程，尤其是在细胞外基质的产生及调控方面意义重大，且TGF-β已被公认为是与胶原代谢关系最密切的细胞因子。胡有谷、陈宏等，应用杂交技术检测了TGF-β对椎间盘Ⅰ、Ⅲ型胶原MRA的调节作用。

RESULTS: HIF-1α positively expressed at stratum neuroepitheliale retinae and purpurogenous membrane in the embryonic phase. Additionally, HIF-1α still positively expressed at stratum neuroepitheliale retinae and purpurogenous membrane, especially in ganglionic cells and inner plexiform layer, in early development.

结果：胚胎期视网膜神经上皮层及色素上皮层均有低氧诱导因子1α阳性表达，生后发育早期视网膜神经上皮层及色素上皮层也可见低氧诱导因子1α阳性表达，以神经节细胞、内网层更明显，随着发育进展，其阳性表达主要位于视网膜节细胞层。

Objective To review the effect of the inflammatory factor and adherence factor on pyretic syndrome tumor by the treatment of QingreXiaotansanjie, through establish the S180 tumor model of TCM pyretic syndrome by alcohol, and to approach the mechanism of action about the pathogenic heat affect tumor'growth and development.

目的通过利用乙醇干预建立热邪干预下S180肉瘤模型，观察清热消痰散结法对热邪干预下S180肉瘤在粘附分子、炎性因子及血管内皮生长因子等方面的影响，探讨热邪对肿瘤发生发展的作用机制。

Objective To review the effect of the inflammatory factor and adherence factor on pyretic syndrome tumor by the treatment of Qingre Xiaotansanjie , through establish the S180 tumor model of TCM pyretic syndrome by alcohol, and to approach the mechanism of action about the pathogenic heat affect tumor'growth and development.

目的通过利用乙醇干预建立热邪干预下S180肉瘤模型，观察清热消痰散结法对热邪干预下S180肉瘤在粘附分子、炎性因子及血管内皮生长因子等方面的影响，探讨热邪对肿瘤发生发展的作用机制。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。