四环素

To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G－ bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50～97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果：G－杆菌比例居多，条件致病菌和酵母样真菌检出机会显著增高；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和克雷伯菌等G－杆菌对喹诺酮类药物的耐药率在50％～97.7％，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50％以上，链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

Twenty clones showed a high level of tetracycline resistance (over 200 microgram tetracycline per ml).

测定了这些含有重组质粒的菌株抗四环素能力，其中有4株在平板上抗四环素水平超过225微克/毫升。

Results Three kinds of veterinary drugs (erramycin,tetracycline,stilboestrol)were detected in the raw meat.The detection rate of terramycin was 5.13%,and the detection rate of stilboestrol and tetracycline was 2.56% and exceeded the national standards.However,aureomycin and hydroxymethyl tertbutyladrenergics were not detected.

结果 共检测出3种兽药(土霉素、四环素和己烯雌酚)残留，金霉素和盐酸克伦特罗未检出；检出率分别为土霉素5.13%，四环素、己烯雌酚为2.56%；残留量均超出中国相应标准。

objective: the clinical date of 60 cases of early syphilis were analyzed.and summed up with the morbid condition ,types of tetter and therapeutic effect.method:all patients were divided into four groups and offered benzathine benzylpenicillin,ceftriaxone, tetracycline and azithromycin respectively.result: the cure risks of the groups treated with benzathine benzylpenicillin or ceftriaxone were all 100 percent, and no repellency in serum of the patients treated with ceftriaxone, the cure risks of the groups treated with tetracycline or azithromycin were all 80 percent.conclusion : it is indicated that benzathine benzylpenicillin and ceftriaxone were all of the best effective drugs.

目的：对60例早期梅毒患者发病情况、皮疹类型、治疗效果进行临床分析和总结。方法：分别采用苄星青霉素、头孢曲松、四环素及阿奇霉素治疗。结果：苄星青霉素、头孢曲松组，临床治愈100%，头孢曲松组无血清学抵抗，四环素、阿奇霉素临床治愈80%。

For mid-degree four wreaths plain tooths arriving depth change countenance, fluorine spot tooth etc., for example flush, hair ash, nigrescent time of bleach of four wreaths plain tooths is long, ineffective.

对於中度到深度四环素牙变色、氟斑牙等，比如发红、发灰、发黑的四环素牙漂白时间长，效果不佳。

Methods The adult parodontitis may use the armor ni...

方法成人牙周炎可以采用甲硝唑凝胶、二甲胺四环素纤维膜、二甲胺四环素凝胶、强力环素聚合物、洗必泰薄膜等各种局部给药方法。

Methods: Experimental mice were perfused with different dosages of tetracycline. Eighteen hours later, the serum levels of ALT, AST were measured and the liver tissues were observed by photics microscope to find the relative suitable dosage that can obviously induce acute liver injury. Then the suitable dosage was given in the same way, and the levels of ALT, SOD, MDA, GSH-PS, IL-18 in serum were measured 18, 36, 54, 72 h later respectively. The condition of cell apoptosis was analyzed, and the tissues were observed by photics microscope and electron microscope to find the relative suitable time.

先以不同剂量四环素灌胃，18h后检测小鼠血清ALT、AST水平并进行光镜观察，探索导致明显急性肝损伤的相对合适剂量；再以相对合适剂量四环素灌胃，18、36、54、72h后分别检测小鼠血清ALT、SOD、MDA、GSH-PX、IL-18水平及肝细胞凋亡情况，并进行光镜、电镜观察，探索导致明显急性肝损伤的相对合适时间及可能机制。

Simultaneous determination of N, N-Dimethylaniline and phenol in wastewater by high-performance liquid chromatography with chemiluminescence detection; 2 rapid determination of rudimental trace aniline in indigotine by reverse phase HPLC; 3 determination of the levels of tetracycline and oxytetracycline residues in liver tissue by HPLC-CL; 4 rapid determination of Shikimic acid in taxodium distichum by ion-suppression reversed-phase HPLC.

第二节是高效液相色谱及其与化学发光柱后检测技术在药物分析中的应用，研究了四环素、土霉素的HPLC-CL方法，应用于动物肝组织中四环素、土霉素残留量的测定；并研究了用离子抑制-反相高效液相色谱法快速测定落羽杉中的莽草酸的新方法。

Methods The resistance of Salmonella isolates were detected by drug susceptibility tests with KirbyBauer diffusion method. PCR was designed to detect tetA, tetB, tetC, tetD, tetE, tetG and tetK. The amplified products were sequenced and alignment analysis was performed.

用KB法测定分离株对四环素等21种抗生素的耐药情况，用PCR方法检测四环素耐药基因tetA、tetB、tetC、tetD、tetE、tetG及tetK，并对扩增产物进行测序。

Methods The resistance of Salmonella isolates were detected by drug susceptibility tests with Kirby Bauer diffusion method. PCR was designed to detect tetA, tetB, tetC, tetD, tetE, tetG and tetK. The amplified products were sequenced and alignment analysis was performed.

用KB法测定分离株对四环素等21种抗生素的耐药情况，用PCR方法检测四环素耐药基因tetA、tetB、tetC、tetD、tetE、tetG及tetK，并对扩增产物进行测序。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。