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WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因而得名WD40;介于生长激素和WD一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆,形成了一个螺旋桨式与每个刀片是一个四叶片结构组成若干链反平行的β-片;与数份检测实例假设,形成了聚大结构,每个WD40重复序列形成了前三个一个刀片和绞线的最后在未来的刀片链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留的建议,配合和其他蛋白质的相互作用/或小配体; 7重复副本,目前这条路。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因此得名WD40;之间的生长激素和WD是一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆性;形式与每个刀片是一个四叶片组成的几个类似结构的螺旋桨,搁浅反平行β-负债表;很少检测副本实例假设,形成了聚大结构,每个WD40重复序列形成了前三个链的一个刀片,并在未来的刀片上链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留物,则建议协调与其他蛋白质和/或小配体; 7重复副本存在于相互作用这条路。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are propos

WD40域,在真核蛋白质的数量发现,涵盖了包括各种功能适配器/信号转导,mRNA前体细胞骨架组装加工和管理模式;通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长,因而得名WD40;介于生长激素和WD一个保守的核心,作为一个稳定的螺旋桨式平台,可以绑定的蛋白可以稳定或可逆,形成了一个螺旋桨式与每个刀片是一个四叶片结构组成若干链反平行的β-片;与数份检测实例假设,形成了聚大结构,每个WD40重复序列形成了前三个一个刀片和绞线的最后在未来的刀片链,最后C -末端WD40重复完成了第一WD40重复叶片结构,创造螺旋桨的封闭环结构,对螺旋桨顶部和底部表面残留的建议,配合和其他蛋白质的相互作用/或小配体; 7重复副本,目前这条路。

Based on the theoretical model coupling Maxwells equation with the rate equation of 4 level inverted population, the numerical simulation is made via the FDTD method and MATLAB programs. The simulation results show that 1. With the increase of the pumping rate, both the localization of the electric field and the spectrum mode numbers will change; 2. The lasing threshold decreases by increasing the size or concentration of the scatters; 3. The lasing threshold also decreases by increasing the size of samples or strengthening the sample randomness.

在理论和实验研究的基础上,利用麦克斯韦方程与四能级反转粒子数的速率方程相耦合的理论模型,采用时域有限差分方法和MATLAB程序对随机激光泵浦阈值特性进行了数值模拟与计算,模拟结果显示:随着泵浦速率的增大,出现了阈值前后电场强度局域态及频谱模式数的改变;随着散射体粒径的增大,浓度的增大,阈值呈现下降的趋势;随着样品长度的增大,随机强度的增强,阈值也呈现下降的趋势。

The present study is involved in the expression of vitronectin , a ligand of integrin, on human spermatozoa and its role in fertilization; the expression of integrin α〓、α〓、β〓 sbunits on human and mouse oocytes and their relationship with maturation of oocytes; the reorganization of cytoskeletal protein, actin, of mouse oocytes mediated with RGD peptide binding with integrins; the roles and mechanisms of integrins in activation of mouse oocytes as trasmembrane signaling receptors, using the methos of cell culture, immunohistochemistry, flow cytometer, laser confocal microscope.

本课题采用细胞培养、免疫组化、流式细胞术、激光共聚焦显微技术进行以下四个方面的研究:整合素配体玻连蛋白在人精子的表达及其与精子功能状态及受精的关系:整合素〓在人、小鼠卵的表达及其与卵的成熟程度的关系:整合素介导小鼠卵内actin骨架蛋白的重组;整合素介导卵激活的早、晚期事件,包括卵细胞内钙离子浓度的变化及孤雌发育胚的形成,并探讨其机制。

This plate of spice spaghetti, you can find it everywhere in italy, and this little package of mixing spices is easy to buy as well. The spices inside are: dry garlic, dry chilly pepper, dry black pepper, and a lot of parsley. They are simple but after you fry them together with the oil they'd become amazingly tasteful.

这道香料面在义大利各处都吃的到,像这样的混何香料包到处也都买的到,里面的内容物很简单:乾大蒜,乾辣椒,胡椒,和大量的 xyz软体王巴西利(洋香菜,现在顶好超市都买的到),以上这四样简单的东西混合之后用油爆香出来的美味是无与伦比的!

Therefore, the EL spectra of (Znq_2)_4 is wider than that of Znq_2. 4._2 was synthesized. The analysis of molecular spatial structure and the characterization of material performance of_2 and Liq showed that two Liq molecules and two Naq molecules were connected by Na-O-Na bond bridges to form_2. Compared with Liq,_2 exhibits stronger rigidity in planar molecular structure, larger steric hindrance and intermolecular distance, and much smaller molecular polarity, thus resulting in much longer fluorescence lifetime, much higher fluorescence quantum efficiency, wider energy bandgap and better film formability. When used as light-emitting layer in OLED,_2 shows lower formation probability of excited dimmer and exciplex formation than Liq, thus emits bluer light with higher current efficiency than Liq. When_2 ultrathin film is used as electron injection layer in OLED, it exhibits higher current density, higher luminance, lower turn-on voltage and higher current efficiency than Liq ultrathin film for the existence of sodium ions in_2 ultrathin film. 5. The summarization the relationship between molecular spatial structure and material performance of Alq_3,(Znq_2) and Liq, lead the conclusion that the molecular spatial structure of Mq_n affects its material performance in such aspects as the rigidity of planar molecular structure, intermolecular interaction, molecule stacking mode and intermolecular distance.

制备了_2,通过对_2和Liq的分子空间结构与性能进行分析与讨论,发现_2是通过两个Na-O-Na键桥将两个Liq和两个Naq连接构成的,其分子平面结构的刚性程度强于Liq,空间位阻大于Liq,分子之间的距离大于Liq,分子极性远远小于Liq;_2的荧光寿命长于Liq,荧光量子效率高于Liq,成膜性优于Liq;_2的禁带宽度比Liq大,光致发光光谱中_2的最大发射峰较Liq发生蓝移;当_2在OLED中作为发光层时,激发二聚体与激基复合物的生成几率远远小于Liq,发的光比Liq更蓝,电流效率大于Liq;_2超薄膜中有Na离子的存在,与Liq超薄膜相比,当其在OLED中作为电子注入层时,具有更大的电流密度,更高的发光强度,更低的阈值电压和更高的电流效率 5、对上述Alq_3、Znq_2和Liq的分子空间结构与材料性能之间的关系进行了归纳总结,认为Mq_n的分子空间结构主要在分子平面结构的刚性程度,相邻分子之间的相互作用,分子堆叠的方式和分子之间的距离这四个方面影响其性能。

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I didn't watch TV last night, because it .

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