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A developmental focus was placed upon the intermediates of the drug such as cephalosporin,antihypertensive,antilipemic,antiulcer,antineoplastic,antiviral,antineuralgic,vitamin and amino acid.

重点发展第二、三、四代头孢菌素中间体、第三、四代喹诺酮类药物中间体、新型抗高血压药物中间体、新型抗高血脂药物中间体、抗溃疡药物中间体、抗癌药及抗病毒药物的中间体、中枢神经药物中间体、手性药物中间体、维生素及各种氨基酸。

The distress of the people, the laborers without bread, the last Prince de Conde engulfed in the shadows, Brussels expelling the Nassaus as Paris did the Bourbons, Belgium offering herself to a French Prince and giving herself to an English Prince, the Russian hatred of Nicolas, behind us the demons of the South, Ferdinand in Spain, Miguel in Portugal, the earth quaking in Italy, Metternich extending his hand over Bologna, France treating Austria sharply at Ancona, at the North no one knew what sinister sound of the hammer nailing up Poland in her coffin, irritated glances watching France narrowly all over Europe, England, a suspected ally, ready to give a push to that which was tottering and to hurl herself on that which should fall, the peerage sheltering itself behind Beccaria to refuse four heads to the law, the fleurs -de -lys erased from the King's carriage, the cross torn from Notre Dame, Lafayette lessened, Laffitte ruined, Benjamin Constant dead in indigence, Casimir Perier dead in the exhaustion of his power; political and social malady breaking out simultaneously in the two capitals of the kingdom, the one in the city of thought, the other in the city of toil; at Paris civil war, at Lyons servile war; in the two cities, the same glare of the furnace; a crater-like crimson on the brow of the people; the South rendered fanatic, the West troubled, the Duchesse de Berry in la Vendee, plots, conspiracies, risings, cholera, added the sombre roar of tumult of events to the sombre roar of ideas.

人民的疾苦,没有面包的劳动人民,最后一个孔代亲王的横死②,仿效驱逐波旁家族的巴黎而驱逐纳索家族的布鲁塞尔,自愿归附一个法兰西亲王而终被交给一个英格兰亲王的比利时,尼古拉的俄罗斯仇恨,站在我们背后的两个南方魔鬼西班牙的斐迪南和葡萄牙的米格尔,意大利的地震,把手伸向博洛尼亚的梅特涅,在安科纳以强硬手段对付奥地利的法兰西,从北方传来把波兰钉进棺材的那阵无限悲凉的锤子声音,整个欧洲瞪眼望着法国的那种愤激目光,随时准备趁火打劫、落井下石的不可靠的盟国英格兰,躲在贝卡里亚背后拒绝向法律交出四颗人头的贵族院,从国王车子上刮掉的百合花,从圣母院拔去的十字架,物化了的拉斐德,破产了的拉菲特,死于贫困的班加曼·贡斯当,死于力竭的卡齐米尔·佩里埃,在这王国的两个都市中棗一个思想的城市,一个劳动的城市棗同时发生的政治病和社会病,巴黎的民权战争,里昂的奴役战争,两个城市中的同一种烈焰,出现在人民额头上的那种类似火山爆发的紫光,狂烈的南方,动荡的西方,待在旺代的德·贝里公爵夫人,阴谋,颠覆活动,暴乱,霍乱,这些都在种种思潮的纷争之上增添了种种事变的纷起。①在法国一八三○年革命中,拉斐德是自由保王派,波林尼雅克是被推翻的查理十世王朝的内阁大臣。②孔代,波旁家族的一个支系,一八三○年孔代亲王被人吊死在野外,未破案。

Archbishop Samson of Reims acted for Eleanor. On 21 March, the four archbishops, with the approval of Pope Eugenius, granted an annulment due to consanguinity within the fourth degree (Eleanor and Louis were third cousins, once removed and shared common ancestry with Robert II of France ).

兰斯大主教萨姆森站在埃利诺一方。3月21日,在获得教皇尤金三世的批准之后,四个大主教将解除婚姻的协议送达双方的第四代血亲手中(埃利诺和路易的第三代堂表兄弟姊妹,曾经被取消,与法兰西的罗伯特二世有着共同的祖先)。

The study focuses on "value diversity", and explores it step by step with a route of "Review -Rethink and Criticism -Construction and Transcendence -Application"From a historical perspective, the study reviews and summarizes western educational evaluation theories and technology development, describes evaluation methods of so-called first three generations evaluation methods, and analyzes historical critique of them, including their failure to accommodate value-pluralism, a tendency towards managerialism, and the overcommitment to the scientific paradigm of inquiry; and then further points out that the fourth generation evaluation methods can be introduced for their effective response to problems of value-pluralism. The study focuses on the characteristics and ideology of the fourth generation evaluation theory; based on which, the research work investigates the social and cultural foundations of education evaluation theory and technology formation development from the dimension of the evolution of values foundation, the impact of social ideology and methodology conversion.

研究从历史的视角回顾、梳理了西方教育评价理论与技术的发展,对称之为前三代评价的方法进行了描述,并分析了历史上对这些早期评价方法的批判,包括对价值多元化的排斥问题、管理主义倾向、对调查的科学范式的过度推崇等;进而指出,第四代评价方法能够有效回应价值多元化问题而被引入,论文重点探讨了第四代评价理论的思想及特点;在此基础上,从价值基础的演变、社会思潮的影响和方法论的转换等维度考察了教育评价理论与技术形成发展的社会文化基础。

Wang Zhentang: Our the 2nd generation gets online to just had been not sent originally, bannerer than the competitor, the 3rd generation gets online to predict to be rolled out inside year originally, still can continue to precede they, the 4th generation can precede likewise.

王振堂:我们的第二代上网本刚刚已经发不了,比竞争对手领先,第三代上网本预计年内推出,还会继续领先他们,第四代同样会领先。

The first generation of barracks were underground bunkers built with cements and reinforced concretes in the early 1970s; the second generation of barracks became blockhouses with sleeping quarters built on the ground, which are used as warehouses now; the third and fourth generations of barracks were modernized barracks, but they too have been turned into memorial halls and rooms of honor; the fifth generation is an innovatively designed three-storied building, in which spring beds has replaced the Chinese heatable brick beds and large boiler has replaced old-typed stove.

走进院内,一栋错落有致的三层小阁楼展现眼前,这已是哨所的第五代营房。五代营房忠实地记录着30多年的风雨历史。第一代营房是上个世纪70年代初用水泥钢筋浇铸的地下工事;第二代营房是地面上修筑的炮楼带宿舍的住房,现在已做了仓库;第三代、第四代营房是现代制式营房,但也变成了纪念馆、荣誉室;第五代营房是设计新颖的三层楼房,室内的钢丝床代替了小火炕,大锅炉代替了土炉子,暖气烧得热乎乎。

The four articles show the preliminarily philosophical transmutation on the view of moral between heaven and human made by Confucius on the basis of the ideas of heaven and human formed from the Xia, Shang,Western Zhou dynasties to the Spring and Autumn period; they reveal Confucius' orientation to think which transformed the traditional heaven as dominator into the moral heaven, and transformed the relationship between the subject and the metaphysical existence from external transcendence to innerness; thus they relieve Confucius as a keen and profound thinker at that time.

本文通过对帛书易传《二三子问》、《易之义》、《要》、《缪和、昭力》四篇的分析,认为帛传四篇为孔子《易》论,其中包涵着《论语》、《孔子集语》、传世本《易传》等反映孔子思想的传世文献所隐微罕见的天人道德观念;帛传四篇表现了孔子在涵括三代以至春秋新旧天人观念的基础上对于天人内涵的初步的哲学改造,反映了孔子将传统的主宰之天转化为道德之天、并将传统的主体对于形上存在的外在超越关系转化为内在超越关系的致思取向,从而凸显了孔子作为当时敏锐而深邃的思想家的形象;帛传四篇所涵具的孔子天人道德思想补足了三代天命德政观与思孟天道性命思想之间的逻辑缺环,是经由曾子而达致《中庸》、郭店儒家简、《孟子》乃至传世本《易传》所体现的天道性命思想高峰的理论根据。

The four articles show the preliminarily philosophical transmutation on the view of moral between heaven and human made by Confucius on the basis of the ideas of heaven and human formed from the Xia, Shang, Western Zhou dynasties to the Spring and Autumn period; they reveal Confucius' orientation to think which transformed the traditional heaven as dominator into the moral heaven, and transformed the relation- ship between the subject and the metaphysical existence from external transcendence to innerness; thus they relieve Confucius as a keen and profound thinker at that time.

本文通过对帛书易传《二三子问》、《易之义》、《要》、《缪和、昭力》四篇的分析,认为帛传四篇为孔子《易》论,其中包涵着《论语》、《孔子集语》、传世本《易传》等反映孔子思想的传世文献所隐微罕见的天人道德观念;帛传四篇表现了孔子在涵括三代以至春秋新旧天人观念的基础上对于天人内涵的初步的哲学改造,反映了孔子将传统的主宰之天转化为道德之天、并将传统的主体对于形上存在的外在超越关系转化为内在超越关系的致思取向,从而凸显了孔子作为当时敏锐而深邃的思想家的形象;帛传四篇所涵具的孔子天人道德思想补足了三代天命德政观与思孟天道性命思想之间的逻辑缺环,是经由曾子而达致《中庸》、郭店儒家简、《孟子》乃至传世本《易传》所体现的天道性命思想高峰的理论根据。

Job experts who communicate by letter throw this feasible whole world more distant with sight having faced fourth communicating by letter on behalf of displacement, to look forward to on behalf of moving an insolvable problem coming to resolve 3 G communication system by fourth, the nothing crack realizing the wireless network of commerce , local area network , blue-tooth , radio and television, satcom ultimately is link up and mutually compatible, realize "anybody fond dream switching in a network with any form in any place" really.

这使得全世界通信业的专家们将目光更远地投向了第四代移动通信,以期通过第四代移动通信系统来解决3G无法解决的问题,最终实现商业无线网络、局域网、蓝牙、广播、电视卫星通信的无缝衔接并相互兼容,真正实现&任何人在任何地点以任何形式接入网络&的梦想。

Segregation analyses were carried out in selfed T1 generationof S6 and S7 transgenic rice lines and T1,T2,T3,T4 generations of S8 transgenic rice lines,bothMendelian and non-Mendelian segregation of transgenes occurred.

对S7、S6基因在T1代、S8基因在T1、T2、T3、T4后四代中的分离进行分析,结果表明孟德尔式和非孟德尔式的分离现象均有发生。S8基因在转基因水稻T0、T1、T2代的表达分析结果表明,S8基因编码产物P8和P8′能够稳定地在转基因水稻当代及其后代中表达。

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