四

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

Two of the four alcohol oxygen atoms O3 in theligands act as oneμ2 bridged atom and the other two O6 act asμ3 bridge to link to Cuatoms together, resulting in the tetranuclear structure.

而立方烷型四核铜骨架配合物是分子中四个Schiff碱配体各提供一个亚氨基N、一个酚基O和一个醇羟基O，与四个Cu一起形成立方烷型四核铜骨架。

But the electrochemical results show that complexes exhibitcompletely irreversible redox behaviour which is different from thatfound in diiron proteins. 1.3 To obtain the diiron species which are stable to elec-trochemical reduction, a series of new tetranuclear cage ironspecies containing two 〓 cores, with using hexadentatepolybenzimidazole ligands, were synthesized and characterized by vari-ous spectroscopic methods. Their physical properties have been investi-gated. The crystal structures of 〓〓tetrakis (benzimidazol-2-ylmethyl)-1, 4-diaminobutane and 〓,〓-tetrakis ( N-ethylbenzimidazol-2-ylmethyl )-1, 4-diaminobutane were determined. They contain two 〓 cores which arelinked to each other by -〓-chain in the ligands.

1.3为了获得电化学还原稳定双核氧桥联Fe化合物，使用六齿配体合成了一系列含有两个〓单元四核笼状化合物，并用各种谱学手段表征了它们，还研究了它们的物理化学性质确定了〓L=N，N，N'，N'-四(苯骈咪唑基-1，4-丁二胺和〓，〓四-1，4-丁二胺化合物的晶体结构，它们含有两个〓单元，其中两个〓单元是通过配体的〓链桥联成四核笼状结构。

Because the CMYK color business card printing and making basic membership card is based on the dot to overprint colouration and instead use spot color is basic to business card printing and membership card production, although typically spot color is only partial use of the image, but valuation, it is conventional to general printing inks price to estimate; in addition, if the same suites have four business card printing and membership card making color, cards and membership cards for the purpose of making is tantamount to another color, if the business card printing and membership card making machines have no spare business card printing and membership card production unit (for example, less than four color business card printing and membership card making machine or four-colour business card printing and membership card making machine), you have to spend double the amount of real time business card printing and membership card production cost is higher.

因为CMYK四色制卡和会员卡制息根基因此网不背叠印呈色，而搁置专色则根基以实不天制卡和会员卡制息，尽管凡是专色只是在图像的部分搁置，但估价时，不惯上却因此凡是印墨的两倍代价来估算的；此外，如果同版背还来有了四个制卡和会员卡制息色，差制卡和会员卡制息而言不离即是众了一个颜色，如果制卡和会员卡制息机操纵众余的制卡和会员卡制息单位（如超出四色的制卡和会员卡制息机或四色制卡和会员卡制息机），不离又给众花一倍的工夫来制卡和会员卡制息，不败本也不离更高了。

More and more financing and technology are plough into the tradition machine for exerting efficiency and prompting precision rapidly,acquire well impression.

为了充分发挥江西第四机床厂效能，迅速江西第四机床厂加工技术与第四机床，越来越多的江西第四机床每年投入大量资金和技术对传统老式组合机床进行技术改造，取得了良好的效果。

The results showed that: at metaphase I, the homoeologous chromosome pairing among different F1 hybrids ranged from 2.0 to 11.4 bi-valents formed by homoeologous chromosomes per pollen mother cell, and very few multivalents, and even very few bivalents were formed by two chromosomes within one genome rather than homoeologous chromosomes in some PMCs; at anaphase I, all biva-lents were disjoined and most univalents were divided.

结果表明在中期I阶段，这些杂种一代的近缘染色体联会变化很大，每个花粉母细胞中二价体形成的数目从平均2个到11.4个不等，甚至在某些花粉母细胞中，还发现极少的多价体和非部分同源染色体所形成的单基因组内二价体；在后期I时，所有的二价体分离，同时多数单价体也分离，分离的二价体和分离的单价体都移向两极，从而形成两组染色体；因为这时完整花粉母细胞中分离的二价体在两组染色体中总是对应出现，从而根据半二价体上染色体重组的位置可以分析在二价体的四分体时期发生在非姊妹染色体之间的多种染色体交换类型，如单交换、三线双交换、四线双交换、四线三交换和四线多交换。

These four constitute a half immanent and half transcendent quaternity, an archetype which I have called the marriage quaternio.7 The marriage quaternio provides a schema not only for the self but also for the structure of primitive society with its cross-cousin marriage, marriage classes, and division of settlements into quarters.

这四者组成了半主观半超验的四位一体，这是一个我叫做四元婚姻的原型。这四元婚姻不仅仅为人自己也为原始社会的结构提供了一副图景，后者有着姑表婚姻，婚姻阶级，并将殖民社区分成四分。

In addition, we'll discuss these four ballades from theme, motive, ways of creation and harmony, compare four different editions, then try to realize the intention of Chopin's creation and melody. Finally, we hope that we can find out whether revolution and unity in Chopin's writing from these four ballades.

另外，藉由主题、动机、创作手法、和声等四个向度来探讨这四首叙事曲，并比较四种不同的乐谱版本，推论出萧邦当时创作上的意图与如何适合於乐曲的个人诠释之浅见，最后，期望可从这四首叙事曲发现萧邦在乐曲创作上有无创新性与统一性。

We proposed that the non-adiabatic passage at zero-crossings of quadrupole splitting would not lead to the great loss of the spin locking signals, and the second-order quadrupolar interaction had significant effects on triple-quantum coherences, which was responsible for the fast decay of the signals; the both experiments and numerical simulations supported this point of view.

另外，在该谱仪上还进行了四极核钠-23的自旋锁定效率的研究；从含时Shr〓dinger方程出发，提出了一个更为确切的四极分裂过零处的绝热通过判据，并指出四极分裂过零处的非绝热通过不会导致锁定信号的快速消失，四极相互作用的二阶项对三量子相干的影响不能忽略，它是引起锁定信号快速消失的原因；实验和数字模拟的结果证实了这个理论。

The second regiment of foot-guards had lost five lieutenant-colonels, four captains, and three ensigns; the first battalion of the 30th infantry had lost 24 officers and 1,200 soldiers; the 79th Highlanders had lost 24 officers wounded, 18 officers killed, 450 soldiers killed.

护卫步兵第二联队丢了五个中校、四个上尉和三个守旗官，步兵第三十联队第一营丢了二十四个官长和一百十二个士兵，第七十九山地联队有二十四个官长受伤，十八个官长丧命，四百五十个士兵阵亡。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。