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KM strain mice immunosuppressed with 7. 5~10mg/L DEX in drinking water had the higher oocysts output and fewer dead than other groups.(4) There was no significant difference infection rate between groups inoculated with different number CSO and groups inoculated CSO with conserved different time. Trial were divided into control, groups of 50mg/kg /d, 100 mg/kg /d and 200 mg/kg /d dose of the drug to study the anticryptosporidial activities of nitazoxanide in an immunosuppressed mice model. The experimental results showed the treatment with 200mg/kg bw /day was significant inhibition of oocyst excretion. To detect the two cryptosporidiums strain C.

实验结果表明:C.parvum虫种能够感染上本实验所采用的BALB/c和昆明小白鼠两种小鼠,而C.andersoni没有能够感染本次实验小鼠;且从小鼠感染后的排卵囊量和小鼠的生存状态来看,采用5~6周龄的KM鼠能获得最大量的隐孢子虫卵囊,小鼠的死亡数最少;每升饮水中地塞米松量为7.5mg~10mg组比12.5mg以上组小鼠死亡数量少,比5mg/L以下组排卵囊数量多;接种不同卵囊数和卵囊的保存时间这两个参数均对小鼠受感染后的排卵囊情况影响不大。

It was found that the process of secretion can be divided into three phases in rat gonadotropes and pancreatic β cells. The three phases correspond to rapidly releasable pool , slowly releasable pool and unprimed pool , respectively.

在大鼠促性腺激素细胞和胰腺β细胞上观察到,它们的分泌都可分为三个阶段,这三个阶段分别对应于快速分泌囊泡池、慢速分泌囊泡池和未启动囊泡池。

Different strains have different reaction to the delay of oviducts in body after animal death. After 10min delay C57BL/6 mouse oocytes have death rate of 56.5%,significantely higher than Kunming mouse (47.6%);Spontaneous activation rates were respectively 13.3% and 46.0%, C57BL/6 were obviously lower than Kunming mouse.4. The oviducts were obtained after being delayed 5min 24h after the mice were injected with hCG. The oocytes were cultured in CZB. About 81.1% occurred spontaneous activation, evidently lower than parthenogenetic rate (96.4%) with SrCl_2. Spontaneous activable oocytes had high cleavage rate(93.2%) and 4-cell rate(87.3%). However, spontaneous activable oocytes had blastula development rate(18.7%) as low as parthenogenetic oocytes by SrCl_2(22.9%).

不同品系小鼠卵母细胞对输卵管在体内滞留产生的反应不同,滞留10min C57BL/6系小鼠卵母细胞死亡率为56.5%,显著高于昆明鼠(47.6%);自发激活率分别为13.3%和46.0%,C57BL/6系小鼠显著低于昆明鼠。4.hCG后24h体内滞留5min卵母细胞在CZB中培养自发激活率为81.1%,显著低于SrCl_2孤雌激活率(96.4%);自发激活的卵母细胞有较高的卵裂率(93.2%)和4-cell比率(87.3%),但囊胚率(18.7%)较低,同卵龄的卵母细胞经SrCl_2孤雌激活囊胚发育率为22.9%,差异不显著。

Results Cribriform and trumpet-shaped epithelial stomata were scattered on the pineal capsule.

结果 在大鼠松果体囊表面发现存在筛状囊上皮孔和喇叭口状囊上皮孔。

Cribriform epithelial stomata were seen mostly in 1.5-month old rats.

筛状囊上皮孔主要存在于1.5月龄大鼠的松果体囊上皮,是由许多密集排列的囊上皮细胞周边部细胞膜凹陷形成的圆形孔洞,筛孔直径200—500nm;喇叭口状囊上皮孔见于1.5月龄和12月龄大鼠的松果体囊表面,由相邻上皮细胞向松果体内部凹陷,形成圆形或椭圆形开口,孔径1~4脚。

Objective To establish rat model with polycystic ovary with two different methods:testosterone plus human chorionic gonadotropin and progestogen plus HCG,compare the rat models induced by testosterone plus HCG with the patients with polycystic ovary syndrome in the aspects of ovarial morphous and gonadal hormone,and investigate whether testosterone with HCG is the effective method to establish rat model with polycystic ovary syndrome,than compare two methods(T+HCG and P+HCG)finally to draw a conclusion if there are any difference or similary between the two methods and which one is more ideal and convenient.Methods 60 SD female rats of 23 days were divided into three groups in random.

目的 本实验用睾酮联合绒毛膜促性腺激素及炔诺孕酮联合HCG两种方法分别建立多囊卵巢大鼠模型,将模型鼠的卵巢形态及血清激素方面改变与人类多囊卵巢综合征的病理改变加以比较,探讨睾酮联合HCG是否是建立多囊卵巢大鼠模型的有效方法,并比较两种造模法是否存在异同点,判断哪一种造模方法更为理想及简便有效。

The expression of AT2R gene can be regulated efficiently in vivo by local delivery of MSC with dual-stable expression of AT2R gene, thus reduces the formation of intimal hyperplasia.④AT2R gene can influence the expression of ECM and significantly promote the cellular apoptosis in the injury rat carotid artery.⑤These data demonstrate the clinical potential of AT2R regulatable expression to prevent restenosis after PCI.

研究结论:(1)与VSMC直接接触可以诱导MSC向血管成分细胞分化;(2)构建的Dox-on可调控的MSC细胞株诱导活性可靠,使外源AT2R基因的表达处于有效的主动控制下;(3)局部导入MSC不影响球囊损伤后大鼠颈动脉新生内膜增生;(4)由MSC介导的AT2R可调控表达受到Dox的良好调控,可有效抑制球囊损伤后大鼠颈动脉新生内膜增生;(5)AT2R影响血管损伤后修复时ECM成分的表达,并促进细胞凋亡的发生,可能是AT2R介导抑制新生内膜形成的机制。

We simply give up some of the plants to the greedy mouths of the omnipresent pocket gophers (last year we lost 3% of the potato plants).

我们简单的放弃一些植物留给无处不在的贪吃囊鼠(去年我们损失了土豆植物的3%)。

He could take a community and run it over and over again in different combinations, making ponds without algae, woods without termites, grasslands without gophers, or just to cover the bases, jungles with gophers and grasslands with algae.

他可能选择一个群落,一遍一遍地以不同的组合来操纵它,制作没有水藻的池塘,没有白蚁的森林,没有囊地鼠的草地,或只是控制这块基地,制作有囊地鼠的丛林,有水藻的草地。

A Gambian giant pouch rat receives the scent of a suspected anti-personnel mine in a minefield near the town of Vilancoulos, 450 km north east of the capital Maputo in Mozambique.

一只冈比亚大囊鼠,在莫桑比克首都马普托东北面四百五十公里的维兰库卢什镇附近一个地雷区,嗅到一枚可疑杀伤性地雷的气味。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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