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Recombinant endostatin is a specific inhibitor of chick chorioallantoic membrane angiogenesis and human vitelline vein endothelial cell ECV-304 proliferation. The recombinant endostatin regressed established syngeneic B16 melanoma tumor in mice.

重组内皮抑素能够抑制鸡胚尿囊膜血管生成和人脐静脉内皮细胞ECV-304的增殖,在小鼠体内实验中对黑色素瘤产生良好的抑瘤效果(P<0.01)。

MAIN OUTCOME MEASURES: The amount of trypan blue absorbed by the CAM. RESULTS: The correlation coefficient between CAM-TB score and Draize eye irritation was 0.925 9. Glycerol had no eye irritation potential, while acet, alcohol, methanol and DMSO had.

结果:鸡胚尿囊绒膜-锥虫蓝吸收法与体内兔眼刺激实验评分结果相关性很好(R2=0.925 9)。5种常见有机溶剂未稀释时,甘油无眼刺激性,丙酮、乙醇、二甲基亚砜、甲醇均有较高刺激性。

Methods The chemical hypoxia was induced by incubation of U251 cells with cobalt chloride.

以氯化钴模拟缺氧,采用RT-PCR、免疫细胞化学方法分别检测缺氧诱导因子-1α和血管内皮生长因子mRNA和蛋白的表达,鸡胚绒毛尿囊膜模型检测缺氧时胶质瘤细胞血管生成情况。

Heart neoplasms ; yolk sac tumor ; endodermal sinus tumor

心脏肿瘤;卵黄囊瘤;内胚层窦瘤

Tiny sacs within the lungs are responsible for making this happen.

小小的胚囊内肺部有责任使这种情况发生。

Different kinds of mature embryo sacs originate from the different ways ofdevelopment.

APⅣ不同类型胚囊是由不同的发育途径形成的。

The high potassium ferrocyanide solution was added to CAM homogenates and the absorbance was detected by ultraviolet spectrophotometer. The hemoglobin content of CAM homogenates was obtained by reference standards.

分离发育期鸡胚尿囊膜并将其匀浆,加入高铁氰化钾溶液,用紫外分光光度计测量A值,通过标准品计算样品中血红蛋白的含量。

Chicken chorioallantoic membrane ; angiogenesis ; hemoglobin ; potassium ferrocyanide

鸡胚尿囊膜;高铁氰化钾法;新生血管;血红蛋白

The imaging characteristic of each type were also analyzed.

结果:14例中不含脂肪的错构瘤8例、平滑肌瘤2例、多囊性肾瘤2例、海绵状血管瘤1例、中胚层肾瘤1例。

Tooth eruption ; Osteoprotegerin ; Tooth germ ; Dental sac

牙齿萌出;骨保护素OPG ;牙胚;牙囊

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