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To master the ultrastructure of mitochondrion;the molecular structure elements of Oxidative Phosphorylation;electron-transport chain;the coupling mechanism of Oxidative Phosphorylation and electron transport;the main content of chemiosmotic coupling hypothesis;the structure and chemical composition of thylakoid;electron transport and photophosphorylation;the mechanism of photophosphorylation;the evidence of endosymbiotic theory.

掌握线粒体的超微结构;氧化磷酸化的分子结构基础;电子传递链;氧化磷酸化作用与电子传递的偶联机制;渗透假说的主要内容;类囊体的结构;类囊体的化学组成;电子传递和光合磷酸化;光合磷酸化的作用机制;内共生起源学说的根据。

And it is also a check point to understand the physical chemical properties of the unique aggregates.

在没有外加能量的条件下,由单体分子、胶束或双层膜如何自发转变为囊泡,以及自发形成的囊泡的稳定性一直是近期研究的热点,也是弄清这一特殊的聚集体的物理化学性质的瓶颈。

First, For the coronary artery stent, two kinds of loads, including the pressure named 〓 derivatively from the balloon and the counterforce named 〓 on the wall edge of the stent, have been taken into account in the analysis of the stent.〓 and 〓 were changing as the stent expanding. So, the expansion process of the stent could be considered as the process composing of many extremely short equilibrium processes, where 〓 and 〓 could be regarded as constants and the stresses, the strains and the displacements were obtained using NFEA in every processes. Then, the stresses, the strains and the displacements obtained in every processes or steps were added up to get the final structure of the coronary stent.

首先,解决了支架有限元分析的载荷非线性问题,认为医用心血管支架受到两种载荷的作用:球囊直接传递的压力〓和球囊对不锈钢支架丝壁边缘的反作用力〓,这两种载荷在支架分析中必须都考虑进去;〓为非线性载荷,随着支架扩张不断变化,处理时将支架扩张的整个过程看成由37个很短的平衡过程组成,在每个过程中取〓为常量,采用有限元法获得应力、应变、位移,最后将各过程的应力、应变、位移迭加起来就获得了不锈钢支架总的应力、应变和位移;本研究用变分法和有限元法模拟杆件拉伸证明了上述方法是合理的。

Analysis of the incubation fluid showed that 2.4 to 6.4mmol dipeptide disappearedfrom the incubation fluid of per gram of intestine in the first 15 minutes of incubation.

旨在测定:同一浓度下的二肽不同肠段的肠囊各部位的水解差异,及不同的浓度的二肽在同一肠段的不同肠囊部位上的水解差异。

The results reveled that no obvious disruption in the tissue structures of the flavedo and the albedo could be found after the processing by the enzymatic technology developed in this study.

从所摄的照片上看,经本论文确定的酶法工艺处理后,橙子原料中的外果皮和中果皮的组织结构没有受到明显的破坏,而囊瓣结构发生了明显解体,但囊衣的解体程度低于汁胞区的解体程度。

The results showed that the sera samples got from the pigs immunized with Hog cholera haplized virus using bursin as adjuvant have higher antibody titers than those without using adjuvant according to the criterion established here, which is conform to the previous study. This study lay on foundation for standarding the I-ELISA assay established here.

以此方法建立的间接ELISA方法对收集的约120头份血清样品进行检测,结果显示:使用囊素与疫苗共同免疫猪的血清抗体水平明显高于未加囊素组猪的血清抗体水平,与以往的报道一致,为以CSFV重组蛋白作为抗原建立的间接ELISA方法的标准化奠定基础。

The degradating and redistributing of ECM were migration of VSMC and vascular remodeling through inhibiting the production of PDGF-BB and the activation of MMPs so to prevent the vascular stenosis.⑤Orthotopic hybridism in situ: The expression of MMP-3 increased after operation, the tendency and intensity were parallel to the expression of NF-κB. Tongxinluo could decrease the expression of MMP-3 and NF-κB. The study showed that the producting and activating of MMP-3 were modulated by NF-κB. The inhibition to the producting and activating of MMp-3 of Tongxinluo was mediated by inhibiting the activating of NF-κB. Conclusion ①The rabbit vascular stenosis model could be established successfully by plain balloon damage, the operation process was easy, economical and practical.

①单纯球囊损伤可成功建立典型家兔血管狭窄模型,操作方法简单,经济实用;②以VSMC增殖、迁移为主的内膜增厚以及以ECM降解、合成与再分布所致的血管重构是导致受损血管狭窄的根本原因;③通心络能明显抑制VSMC的增殖、迁移和ECM降解、合成,阻止血管内膜增生和血管重构,防止受损血管狭窄;该作用可能与其减少和阻止PDGF-BB的产生和活性,以及抑制MMPs的表达和恢复MMPs/TIMPs平衡有关;④通心络能显著抑制球囊损伤后血管内膜增生和血管重构,可能与其保护血管内皮,改善内皮功能,增加血清NO含量有关;⑤通心络抑制内膜增生和血管重构,减轻受损血管狭窄,还可能是通过抑制NF-κB的活化途径而起作用的。

Objective: To determine if an aggressive approach to coronary revascularisation with oversized balloons is counterproductive, we studied the effect of increasing balloon-to-artery ratio on neointimal hyperplasia following primary stent placement using a non-atherosclerotic porcine coronary overstretch model.

目的:为了确定在冠状动脉重建术中使用过大的球囊这种过于积极的措施是不是有反作用,我们研究了首次支架置入术后增加的球囊比动脉比值对新生内膜增生的影响,模型是没有动脉粥样硬化的猪的过度牵张的冠状动脉。

The objective of this study is to picture the signal tranduction pathway of apoptosis induced by MC so as to further investigate the impact of MC on transcription, expression and regulation of apoptosis gene and the related biological effects; illustrate the toxicological mechanism of MC; as well as discover the new biomarkers invovled.

本研究工作的目的是通过功能基因组分析的技术平台,探讨微囊藻毒素诱导肝组织细胞凋亡的信号转导通路,以便在此基础上,进一步深入研究该毒素对凋亡功能基因在转录、表达、调控水平上的影响,及由此引发的生物学效应;揭示微囊藻毒素的凋亡毒理机制,同时发现新的生物标记物。

According to the results of DLS and cryo-TEM, the decreasing region from start to the minimum is just that of from vesicle formation to monodisperse state, which implies the formation of vesicle inhibits the self-oxidation.

结合光散射、电镜等实验结果,可以发现在复配体系中,邻苯三酚的自氧化速率从开始降低到达到最低点的这一区域正好是囊泡形成的区域,这说明是囊泡的形成抑制了邻苯三酚的自氧化。

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