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The results are in good agreement with available experimental results. The entropy effect on the Gibbs free energies of 6-thioxanthine base is very small and there is little significance for the tautomeric equilibria of the base.

计算结果同已有实验结果一致。6-硫代黄嘌呤异构化的熵效应小，对互变异构平衡几乎没有显著的影响，而焓变对互变异构产生了主要的影响。

Resembles thymine, but easily interconverts to tautomeric form that pairs with guanine.

与胸腺嘧啶相似，但很容易转换成与鸟嘌呤配对的互变异构形式。

The binding behavior and kinetics of uncoupling protein with its ligand, the Fourier-transformation infrared spectra of uncoupling protein and its changes during ligand-binding process, the inhibition of Guanosine 5＇-Tetraphosphate (G-4-P) and Adenine-β-Darabinofuranoside 5＇-triphosphate on the binding of uncoupling protein with GTP were studied.

本文对解偶联蛋白与配基的结合及其结合动力学，解偶联蛋白及其与配基结合过程中的傅里叶变换红外光谱及其光谱变化，鸟嘌呤核苷四磷酸（G-4-P）和9-β-D-阿拉伯糖基呋喃5＇-三磷酸对解偶联蛋白与GTP结合的影响进行了研究。

OBJECTIVE: To evaluate the short-term safety and outcome of 2 different experimental applications of rasburicase 0.2 mg/kg in patients with tophaceous gout not treatable by allopurinol.

目的：评价别嘌呤醇治疗无效的白垩性痛风患者应用拉布立酶0.2毫克/公斤的2个不同实验的短期的安全性和疗效。

Purins as a kind of signal molecular play an important role in the signal transduction of cells.

嘌呤核苷酸作为一种信号分子，在细胞的信号传递中起重要作用。

Ras homolog enriched in brain, a small GTPase, positively regulates the mTORC1 pathway. The GDP-GTP exchange of Rheb has been suggested to be facilitated by translationally controlled tumor protein. Here we demonstrate that human TCTP interacts with human Rheb and accelerates its GDP release in vitro, and that hTCTP activates the mTORC1 pathway in vivo.

丁建平研究组运用体外 GST-pulldown 和鸟嘌呤交换等生物化学实验以及对 TCTP 降低表达和过量表达等细胞生物学实验，证明了人源 TCTP 具有针对 Rheb 的弱 GEF 活性，能正向调控 mTOR 信号通路。

The glucose-6-phosphate dehydrogenase increased during overw intering,indicating that reduced condition of cell might keep the cell in pr oper function even in cold temperature,and also for cryoprotectant synthesis.The changes in trehalase activity showed that low activity was for keeping higher tre halose content and high activity for removing it in the spring.

越冬期间，体内葡萄糖-6-磷酸脱氢酶活性增高所产生的还原型烟酰胺腺嘌呤二核苷酸磷酸，可为细胞在亚低温状态下发挥正常功能以及体内抗冻保护性物质的合成提供还原动力，同时通过调节体内海藻糖酶活性来维持越冬期间较高含量的海藻糖和移除春季体内累积的过多的海藻糖。

Methods C3b sensitized yeast cells and C3b unsensitized yeast cells were used to detect C3b receptors and immune complex on red cells,method of xanthine oxidase was applied to detect SOD activity in red cells.

实验利用低碘饲料和碘化钾去离子水复制了不同碘营养状态的大鼠，采用C3b致敏和未致敏的酵母菌及黄嘌呤氧化酶法分别检测红细胞膜上的C3b受体、免疫复合物及红细胞内SOD的活性。

At present the main treatment is to increase endurance, and actively prevent and treat lung infection, and control fibrosis drug use, such as penicillamine, colchicine, azathioprine, and so on, can also be supplemented by anti-vascular inflammatory drugs, such as low-dose glucocorticoids , vasodilating agents, such as anticoagulants.

目前治疗主要是提高抵抗力，积极防治肺部感染，同时用控制纤维化的药物，如青霉胺、秋水仙碱、硫唑嘌呤等，也可辅以抗血管炎症药物，如小剂量糖皮质激素、扩血管剂、抗凝剂等。

Here we show that purine-mediated signalling triggers both EFTF expression and eye development in Xenopus laevis.

本文中我们发现嘌呤介导的信号触发EFTFs的表达并引发非洲爪蟾眼睛发育。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。