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The experimental results show that the DNA molecule can be adsorbed on the silver colloid particles through the C6N and N7 of adenine, the C=O of thymine and deoxyribose.

同时,实验结果表明DNA分子是通过腺呤上的C6N 和N7以及胸腺嘧啶上的C=O基团吸附在胶体银颗粒上的。

Methods Seven probe drugs were incubated with or without methyl protodioscin respectively in human microsomes. The specific substrates used in this study were caffeine (CYP1A2), dextromethorphan (CYP2D6), tolbutamide (CYP2C9),-mephenytoin (CYP2C19), chlorzoxazone (CYP2E1), coumarin (CYP2A6) and midazolam (CYP3A4). The concentrations of the substrate metabolites (paraxanthine, dextrorphan, 4-hydroxytolbutamide, 4-hydroxymephenytoin, 6-hydroxychlor-zoxazone, 7-hydroxycoumarin and 1-hydroxymidazolam) were determined by HPLC and LC-MS/MS. Results MPD 1-10 μmolL^(-1 had no significant inhibition on the activities of the seven cytochrome P450 enzymes.

将MPD和CYP450酶7种亚型的特异性探针底物咖啡因(CYP1A2)、右美沙芬(CYP2D6)、甲苯磺丁脲(CYP2C9)、s-美芬妥因(CYP2C19)、氯唑沙宗(CYP2E1)、香豆素(CYP2A6)及咪达唑仑(CYP3A4)与人肝微粒体进行孵化反应,采用HPLC和LC-MS/MS法测定对应的7种代谢产物(1,7-二甲基黄呤、去甲右美沙芬、4-羟基甲苯磺丁脲、4-羟基美芬妥因、6-羟基氯唑沙宗、7-羟基香豆素和1-羟基咪达唑仑)的浓度,通过与对照组比较,确定MPD对以上7种酶活性的影响。

This osmosensation of luminal tonicity by ciliary TRPV4 involves apical ATP release and purinergic receptors and induces apical bicarbonate secretion, the main determinant of ductal bile formation.

这种通过纤毛TRPV4引起腔内张力的渗透包含顶端ATP的释放,呤受体,引起顶端碳酸氢盐的分泌,而碳酸氢盐正是管道胆汁形成的主要决定物质。

Gout is a kind of disease for purin metabolized turbulence . If it reiteration for Long time , it will come into being tophus .

痛风是一种由呤代谢紊乱所致的疾病,日久不愈,反复发作则逐渐形成痛风石沉积。

Methods::112 cases of renal transplant recipients were divided into two groups at random .

将112例患者随机分成2组,MMF(2.0 g/d)组和硫唑呤组。

Adefovir dipivoxil was synthesized from adenine and phosphorus trichloride as the starting materials.

我们选择比较经济、合理的方法,设定以腺呤和三氯化磷为起始原料合成阿德福韦酯的工艺路线。

Tungstate competitively inhibits the utilization of molybdenum for the formation of xanthine dehydrogenases.

钨酸盐竞争性地抑制钼的利用以形成黄呤脱氢酶。

In the end, the effects of methylation on the properties of uracil and adenine-uracil base pair have been investigated.

最后,我们研究了甲基化对脲嘧啶单体以及腺呤-脲嘧啶碱基对的影响情况。

Allopurinol is an appropriate long term urate lowering therapy.

呤醇是一种合适的长期降尿酸药物。

Tetraploid veliger were carried out with four chemicals on this scallop in 1998—2000. Tetraploid were induced by inhibition of the polar body and first mitosis with cytochalasin B, colchicine, 6-DMAP and caffeine combined with CB, respectively.

中文摘要:1998—2000年采用细胞松弛素B、秋水仙素、6-二甲基氨基呤(6-DMAP)以及咖啡因等药物抑制虾夷扇贝第一极体(PB1)释放、PB1和第二极体(PB2)释放以及抑制第一次卵裂等方法,诱导虾夷扇贝四倍体。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。