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Initial stage of disease of acerbity blood of high make water can not have any symptoms, but the part can evolve and cause acute arthritis, chalkstone, kidney stone and uric acid nephrosis. The content that 3 health teach 3 · 1 balanced diet, reducing acid of make water of tall purine food is the final result that purine metabolizes, fructose is absorbed can bring about acid of nucleotide of purine of the gland inside body to produce increase too much, promote make water to be generated acerbitily then, reason should be fed less contain the food with much fructose, the intake of daily purine should 50 Mg.

高尿酸血症初期可无任何症状，但部分可演变而诱发急性关节炎、痛风石、肾结石及尿酸肾病。3健康教育的内容3·1均衡饮食，减少高嘌呤饮食尿酸是嘌呤代谢的最终产物，果糖摄入过多可导致体内腺嘌呤核苷酸产生增多，进而促进尿酸的生成，故应少食含果糖多的食物，每日嘌呤的摄入量应50 mg。

RNA editase transforms or modifies the nucleotide of pre-RNA by deaminization, and hydrolytic deaminize C6 amino group of the adenosine at the specific RNA site, changing adenosine to inosine or changing cytosine to uracil,but inosine was recognized as guanine in mRNA.

RNA编辑酶以脱氨方式使得RNA特异位点的腺嘌呤脱氨转变为次黄嘌呤，或者是特异位点的胞嘧啶变为尿嘧啶，而次黄嘌呤在碱基配对时被识别为鸟嘌呤。

Object: The purpose of this study was to supply people with scientific dietary instructions by investigating the change of the content of adenine, guanine, xanthine and hypoxanthine in two Huahuang fish and carp during boil processing. Method The HPLC method was accepted.

目的：通过检测经过水煮的黄花鱼和鲤鱼中腺嘌呤、鸟嘌呤、黄嘌呤、次黄嘌呤的含量，探索在高温水煮过程中嘌呤含量的变化，希望以此为人们的健康饮食提供科学的指导基础。

The reactivity of guanine, adenine and hypoxanthine on electrodes made with different materials is discussed. The rough pyrolytic graphite electrode was selected for the electrochem. study.

本文讨论了鸟嘌呤、腺嘌呤和次黄嘌呤等嘌呤类生物小分子在几种电极上的反应活性，并选用粗热解石墨电极研究了它们的电化学性质。

The content of purines in soup increased sharply during 10 min, increased slowly during 10 min to 60 min. The content of adenine in carp weighed 200 g increased during boiling process, that of guanine was stable, that of total purines and hypoxanthine decreased. The content of total purines and four purines in Huahuang fish decreased during boil processing.

鱼汤中嘌呤含量在10min内迅速升高，10~60min缓慢升高。200g鲤鱼中腺嘌呤含量在水煮加热过程中升高，鸟嘌呤含量无明显变化，总嘌呤和次黄嘌呤组分含量下降，200g黄花鱼的总嘌呤及4种嘌呤组分含量在水煮加热过程中下降。

A method of screening serum of patients of gout and hyperuricemia includes checking purine compound content of xanthine and hypoxanthine in serum to be tested, confirming that serum to be tested is serum of gout patient if xanthine content of 1.00-2.35 mg / L and / or hypoxanthine content of 4.1-16.00 mg / L are contained in serum to be tested and confirming that serum to be tested is serum of hyperuricemia patient if xanthine content of 0.20-1.20mg/L and / or hypoxanthine content of 1.30-3.50mg/L are contained in serum to be tested.

本发明所提供的筛查痛风疑似患者及高尿酸血症疑似患者血清的方法，是检测待测血清中包括黄嘌呤和次黄嘌呤在内的嘌呤化合物的含量，如待测血清中黄嘌呤含量为1.00-2.35mg/L，和/或次黄嘌呤含量为4.1-16.00mg/L，则待测血清为痛风疑似患者血清；如待测血清中黄嘌呤含量为0.20-1.20mg/L，和/或次黄嘌呤含量为1.30-3.50mg/L，则待测血清为高尿酸血症疑似患者血清。

Part II:The electrocatalytic oxidation of guanine, adenine, guanosine-5'-monophosphate and ssDNA was performed in the presence of iron bis(2,2':6',2"-terpyridine) and Fe tris(1,10-phenanthroline) complexes as a homogeneous catalysts with Fe redox couple. The electrocatalytic and electroanalytic properties of guanine with an iron bis(2,2':6',2"-terpyridine) complex was measured by the amperometry method using the rotating disk electrodes. Electropolymerization of iron tris(5-amino-1,10-phenanthroline) complex produced thin polymer films on a gold, platinum, nickel, and glassy carbon electrode.

第二部分利用iron bis(2，2'：6'，2&-terpyridine)和Fetris(1，10-phenanthroline)之金属错合物当作均相的催化剂对於鸟嘌呤、腺嘌呤、5'-鸟嘌呤核苷单磷酸盐(guanosine-5'-monophosphate)和单股DNA进行电催化氧化的研究。iron bis(2，2'：6'，2&-terpyridine)之金属错合物对於鸟嘌呤的电催化和电分析性质可利用计时安培法并使用旋转环-碟电极进行测量。rontris(5-amino-1，10-phenanthroline)之金属错合物可经由电聚合过程所形成的聚合薄膜固定在黄金、白金、镍和玻璃碳电极上。

Comparative studies of electroactive components and voltammetric behaviors different between the MCF-7 cell without estrogen and the MCF-7 cell with estrogen showed that the concentration of the guanine and xanthine bases in the cytoplasm decreased, which resulted in the decrease of secretion ability of the MCF-7 cell without estrogen decreased, and these result in the decreasing of the voltammetric response of the cells, impling that the cell vaibility decreases.

结果发现，去激素MCF-7细胞质中的黄嘌呤和鸟嘌呤浓度降低，使细胞分泌黄嘌呤和鸟嘌呤能力降低，导致细胞和细胞质的伏安信号减弱，说明去激素MCF-7细胞的活性下降；研究了标准雌激素雌二醇、环境雌激素壬基酚和双酚A对去激素培养的MCF-7细胞增殖的影响，发现其均存在剂量-效应关系和时间-效应关系，并且雌激素效应由大到小的顺序为：雌二醇＞壬基酚＞双酚A；同时使用3-(4，5-Dimethylthiazol-2-yl)-2，5-diphenyltetrazolium bromide法验证了电化学法评价雌激素效应的可靠性。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本论文主是采用以鸟嘌呤为原料，经过一系列的酰基化，脱羧，还原等反应作用下最终得到了产物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤；其中的中间体衍生物主要是阐述从以2-氨基-6-氯鸟嘌呤为原料通过在不同的条件下进行溴代与碘代分别合成了另外两种中间体2-氨基-6-溴鸟嘌呤及2-氨基-6-碘鸟嘌呤；还有一部分主要是阐述从以苯乙酮，盐酸氨基脲，苯肼，乙酰乙酸乙酯为原料通过一系列的反应先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛这两个吡唑醛，然后再与2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反应得到了两个新型的吡唑嘌呤席夫碱

METHOD The serum concentrations of AZP metabolite 6-Mercapto prine(6-MP) in different time were determined by reverse phase HPLC,when AZP was used alone and combined with Pred in nine rabbits.The pharmacokinetic parameters of the two groups wer statistically analysed by paired t test.

采用反相高效液相色谱法对单用硫唑嘌呤及醋酸泼尼松与硫唑嘌呤合用后，对家兔体内硫唑嘌呤的代谢产物六巯基嘌呤(6-MP)的血清药物浓度进行了测定，并对两组药物动力学参数进行配对t检验统计处理。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。