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In the rat pheochromocytoma cell line (PC12) and its subclones, D-Asp is synthesized intracellularly, most likely by Asp racemase.

在鼠的嗜铬细胞瘤细胞系及其亚克隆中,D-天冬氨酸在细胞内大多数可能被天冬氨酸消旋酶所合成。

Results Cortical tumors were seen in 9 cases, including adenomatous hyperplasia in 3 cases, adenoma in 4, cortical adenocarcinoma in 2;Medullary tumors were seen in 9 cases, including pheochromocytoma in 5 cases, metastasis in 3, neuroblastoma in 1;interstitial tumors were seen in 9 cases, including myelolipoma in 4 cases, and neurofibroma,cyst, lymphoma, malignant transformation of mesothelioma, malignant mesenchymal tumor in one, respectively.

结果 皮质肿瘤9例,其中肾上腺腺瘤样增生3例,腺瘤4例,皮质腺癌2例;髓质肿瘤9例,包括嗜铬细胞瘤5例,转移瘤3例,神经母细胞瘤1例;间质肿瘤9例,其中骨髓脂肪瘤4例,神经纤维瘤、囊肿、淋巴瘤、间皮瘤恶变、间叶组织来源恶性肿瘤各1例。

We found depolarization of plasma membrane induced vesicle fusion and transmitter release without the involvement of calcium in rat DRG neurons, but not in adrenal chromaffin cells.

我们对一种感觉神经元的研究发现,细胞膜的去极化可以在没有钙离子的参与下直接触发细胞的递质分泌,这种非Ca〓现象在肾上腺嗜铬细胞上不存在。

The remarkable analgesic effects of adrenal medullary chromaffin cell transplantation for pain have been shown in many studies, but it has notreached the status of a standard clinical treatment.

尽管大量研究显示出肾上腺髓质嗜铬细胞移植在疼痛治疗中的显著效果,但将其作为基本治疗方法用于临床还存在许多困难,其中有限的细胞来源是AMCC 移植广泛应用的最大障碍。

Chromaffin cell ; bovine ; culture ; dopamine

嗜铬细胞;牛;细胞培养;多巴胺

Connexin 36 (Cx36) is a new member of connexin family, which is highly expressed in neurons of brain and retina. In addition, Cx36 is also found in the beta cells of pancreatic islets and chromaffin cells in adrenal slices.

Cx36是连接蛋白家族新成员,主要分布在脑组织、视网膜的神经元,也在非神经组织,如胰岛β细胞、肾上腺嗜铬细胞表达。

The morphological changes of cultured bovine chromaffin cells were observed and the dopamine secreted was determined by HPLC to explore the feasibility of gene therapy with adrenal medulla cell transplantation.

为给肾上腺髓质细胞移植治疗帕金森病提供理论依据,观察正常体外培养和冷冻复苏后牛肾上腺嗜铬细胞的形态变化,并检测培养液中的多巴胺含量。

Objective: To study the protective effects of flavonoids from Cuscuta chinensis on oxidative stress in cultured PC12 cells and investigate the mechanism of the effects.

目的:探讨菟丝子中黄酮类组分对氧化损伤的肾上腺髓质嗜铬细胞瘤细胞(Pheochromocytoma,PC12)的保护作用及其可能的作用机制。

The pathology of tumours included 8 cases of phechoromocytoma(1 case appears malignancy),4 cases of ganglioneuroma,4 cases of adrenal myelolipoma, 2 cases of melanoma,4 cases of other lesions. Current median follow up ,available on 19 patients,was 14 months(ranges 3 to 47),no local recurrence and metastases was observed.

术后病理报告:嗜铬细胞瘤8例其中1例恶性),髓样脂肪瘤4例,神经节细胞瘤4例,脂肪肉瘤2例,其它病变4例。3例失访,19例随访3~47个月,平均14±9个月,未见局部复发和转移。

PCI2 cells were treated under glucose deprivation as model group. Method Morphological and cytoflowmetric methods (the mitochondrial transmembrane potential; MEF method) were applied to evaluate the protective effect of SAB. The RNA levels of grp75 were measured by RT-PCR and immunocytochemistry were performed to investigate the expression level of PC12 cells under glucose deprivation and treated by SAB.

以PCl2细胞(大鼠肾上腺嗜铬细胞瘤细胞)的无糖培养建立细胞缺糖损伤模型,MTT法检测细胞的存活率;应用流式细胞仪检测亚二倍体细胞的比率及线粒体跨膜电位的改变;应用免疫细胞化学、RT-PCR法研究细胞内应激蛋白grp75的表达变化,激光共聚焦显微镜观察SAB作用下Ca(上标 2+)的变化。

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