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嗜酸粒细胞

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Methods The levels of IgE,IL-4,histamine in sera and the number of acidophilic cells in blood were detected or countered,the pathohistologic alterations of the main target organs or tissues were examined.

检测死者血中IgE、IL-4、组胺含量和嗜酸粒细胞数量,尸检主要靶器官病理组织学改变。

Results The levels of IgE,IL-4and histamine in sera and the number of acidophilic cells in blood were all in-creased;The asphyxiant sign,the congestion and edema of the epiglottis,a large amount of the lightish yellow mucous fluid with some blood-filaments in the tracheae,pneumochysis,scattered petechiae on the inside surfaces and the bot-toms of both lung lobes were found;cerebromeningeal haemorrhage and cerebral edema were observed under microso-cope.

结果 检血中IgE、IL-4、组胺含量和嗜酸粒细胞数量均显著增加。死者呈窒息征象;气管喉头充血水肿,气管内有大量淡黄色夹有血丝的粘性液体,肺水肿,肺叶间及肺底部散在点状出血;脑膜出血和脑水肿。

Apoptotic eosinophils were added to A549 cells which was pretreated with dexamethasone or RU38486 for engulfment .

将凋亡的嗜酸粒细胞加入到预先用地塞米松或RU38486处理的A549细胞中进行吞噬。

After engulfment apoptotic eosinophils were stained for peroxidase with o-dianisidine and A549 cells were stained with haematoxylin.

吞噬结束后,凋亡的嗜酸粒细胞用邻联茴香胺进行过氧化物酶染色,A549细胞用苏木素加以胞核衬染。

The light microscopy found that the livers pathological damage was milder, the number and the volume of granuloma were smaller than those of the control, the electron microscopy demonstrated that a lot of hepatocytes denatured, fibrous tissues proliferated, eosinophile and lymphocytes infiltrated in the liver.

光镜下观察发现肝脏病变明显减轻,肉芽肿数目少,体积小;电镜观察发现肝组织病变轻微,大部分肝细胞变性,肝纤维组织增生,有嗜酸粒细胞和淋巴细胞浸润。

Bronchial asthma;cold type asthma; heat type asthma; IgE;SIL -- 2R; T -- lymphocyt subpopulations; Eosinophile lung function;clinical study

支气管哮喘;冷哮证;热哮证;IgE;可溶性白细胞介素Ⅱ受体;T淋巴细胞亚群;嗜酸粒细胞;肺功能;临床研究

METHODS: Eighty guinea pigs were randomized into control group, model group, salbutamol treated group and Maxin liquid treated group. Asthma model s were established by ovalhumin. The changes of eosinophile in bronchoalveolar lavage fluid, thromboxane B2 and 6-Keto-prostaglandin F1a in blood, the airway resistance and the pulmonary compliance were observed by Pap staining, radio-immunity , and pulmonary function test instrument of MIL type specially for experimental animal.

实验设正常对照组、模型对照组、复方麻辛组、沙丁胺醇组,选用豚鼠共80只,采用清蛋白造模,并运用巴氏染色法、放射免疫法、MIL型实验动物肺功能测量仪,分别检测肺泡灌洗液中嗜酸粒细胞数、血浆凝血恶烷(TXB2)、6-酮-前列腺素(6-K-PGF1a)以及清蛋白激发后气道阻力和肺顺应性。

Methods 13 patients with rhinopolypus were treated by fluticasone. The expression of PKC and the apoptosis of eosinophlis before and after treatment were detected by flow cytometry, and the normal membrane of nosepiece in 7 healthy subjects was used as control.

13例鼻息肉患者给予丙酸氟替卡松喷鼻治疗,采用流式细胞术检测激素治疗前后鼻息肉组织中蛋白激酶C表达及凋亡的嗜酸粒细胞,并与7例健康正常人下鼻甲黏膜进行比较。

RESULTS: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果: 镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润,组织细胞呈梭形、多边形,胞质嗜酸性颗粒状、放射条纹状或泡沫状,一些大组织细胞质内有多量小淋巴细胞。

RESULTS摘要: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果摘要:镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润,组织细胞呈梭形、多边形,胞质嗜酸性颗粒状、放射条纹状或泡沫状,一些大组织细胞质内有多量小淋巴细胞。

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