嗜睡

Methylmalonic acidemia is an autosomal recessive organic acidemia, which is charactered by various presentations, especially the neurological symptoms such as vomiting, lethargy and so on.

甲基丙二酸血症是一种常见的有机酸血症，属于常染色体隐性遗传，临床表现无特异性，以呕吐、嗜睡等神经系统症状为主。

Methods Sedative amnestic slow induction anesthesia with nasotracheal intubation,cocaine topical anesthesia combined with intraveneous sedative drug was used in 198 patients receiving general anesthesia for uvulopalatopharyngoplasty,during which the patients were asleep but had a...

方法OSAHS患者198例，采用丁卡因表麻+镇静健忘经鼻腔气管插管全麻，给予适度镇静催眠药物使患者嗜睡，保留自主呼吸，能按指令主动配合气管插管。

Results: Neonatal rats in hypoxic-ischemicgroup behaved restlessness, cyanosis, deep and rapid breath, astasia, lethargy, irritation and spasm; There were local pyknosis, fragmentation, dissymmetry, blur or disappearance of nucleoli, raritas of ground substance in left cerebral cortex; but there was no statistic significance in chinese traditional medicine group and sham group. The expression of HIF-1α mRNA in brain tissue of experimental group and chinese traditional medicine group were higher than that in sham group, especially chinese traditional medicine group at 3d; HIF-1α positive cells were found in cerebral cortex and hippocampus. There were more HIF-1α positive cells in experimental group and chinese traditional medicine group and mainly in vascular endothelial cells.

结果 缺氧缺血后大鼠相继表现为烦躁不安、全身发给、呼吸加深加快、站立不稳、嗜睡、激惹或间断发作的痉挛和抽搐；HE染色显示实验组大鼠左侧大脑皮层出现局灶性神经元核固缩，核碎裂，核仁偏位，不清或消失，基质疏松；中药组大鼠脑组织结构基本接近假手术组，无明显水肿和坏死表现；实验组和中药组大鼠脑组织HIF-1α mRNA表达较假手术组明显增加，尤其是中药组实验第3日者；免疫组化显示实验组和中药组各时间点大鼠大脑皮层和海马区均可见不同程度的HIF-1α表达，明显高于假手术组，阳性表达主要在血管内皮细胞，海马和皮层的锥体细胞亦有HIF-1α阳性细胞分布。

According to the 1951 edition of Pharmacology and Therapeutics, it was to be prescribed for narcolepsy , post- encephalitic parkinsonism , alcoholism ,...

二十世纪五十年代，美国政府颁布法令将甲基苯丙胺规定为处方药，根据1951年出版的Arthur Grollman所著的《病理与药理学》一书，它可用于治疗嗜睡，后脑炎，帕金森综合症，酒精中毒，以及肥胖症。

objective to explore the reasonable utilization of cephalosporins in chronic renal failure patients with cephalosporin encephalopathy.method we retrospectively analyzed the clinical characteristics of 29 crf patients,who developed encephalopathic syndrome and was treated with cephalosporin.results the encepha1opathic syndrome include (1)mental confusion in 4 cases;(2)unconsciousness in 2 cases;(3)seizure in 23 cases.physical examination did not show signs of cerebral focal injury.computed tomography of the brain in 29 patients did not show acute lesions.the state of neurotoxicity was completely recovered after discontinuation of cephalosporins.conclusion cephalosporins used in conventional doses or reduced doses can cause temporary encephalopathy in patients with crfwhich might due to prolongation of drug half life.

目的 通过研究慢性肾功能衰竭患者抗生素脑病的发病机制和临床特点，探讨头孢菌素在crf患者中的合理应用。方法 29例crf患者在使用常规剂量或减量使用头孢菌素后出现神经精神症状，诊断为抗生素脑病，将其临床资料进行回顾性分析。结果神经精神症状表现多样：(1)精神异常4例，表现为胡言乱语、烦躁不安、睡眠倒错；(2)意识障碍2例，表现为嗜睡、昏睡、神志不清；(3)癫痫样抽搐23例，表现为肌阵挛、全身抽搐、癫痫样发作；部分患者同时出现几组症状。所有患者均无神经系统定位体征，行颅脑ct检查无急性病变。

Signs for both include hypersalivation, vomiting, lethargy, tremors, difficulty walking, weakness, and death.

临床表现包括：多涎、呕吐、嗜睡、震颤、行走困难、虚弱，甚至死亡。

But the side????effects such as somnolence, hypersalivation, constipation, weight gain, abnormal ECG, nausea, leukopenia decreased significantly.

研究组嗜睡、流涎、便秘、体重增加、心电图异常、恶心呕吐、白细胞减少等因子显著少于对照组，差异有显著性（P＜0.01或0.05）。

But the sideeffects such as somnolence, hypersalivation, constipation, weight gain, abnormal ECG, nausea, leukopenia decreased significantly.

研究组嗜睡、流涎、便秘、体重增加、心电图异常、恶心呕吐、白细胞减少等因子显著少于对照组，差异有显著性（P＜0.01或0.05）。

Please report to your supervisor and avoid to working outside if you take some hypersomnia medicine.

如果服用嗜睡类药品请及时向自己的主管报告，尽可能避免室外工作。

Hypersomnia sleeping disorder is characterized by excessive sleepiness sometimes to the extent that the person finds it difficult to stay awake.

睡眠过度睡眠障碍的特点是有时过度嗜睡的程度的人难以保持清醒。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。