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嗜中性粒细胞

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Bronchoalveolar lavage and wright staining analysis showed that thetotal number of the all inflammatory cells in asthma model group andthe normal control were (36.2±4.6)×10~6/ml and (9.5±1.6)×10~6/ml.There was significant difference between the two groups (p<0.01).Meanwhile, the number of acidophilic cell, macrophage andmacrophage were also increased in asthma model group rather thanneutrophilic granulocyte.

支气管肺泡灌洗和细胞记数显示,哮喘模型组支气管肺泡灌洗液细胞总数为(36.2±4.6)×10~6/ml,与正常对照组(9.5±1.6)×10~6/ml,相比显著增加(p<0.01),同时嗜酸性细胞、巨噬细胞和淋巴细胞增加明显,而中性粒细胞变化不明显。

The atopy asthma was correlated with the number of the eosinophil while the non-atopy with the neutrophil.

特应性哮喘的发病机制与诱导痰中嗜酸粒细胞数相关;非特应性哮喘与中性粒细胞数相关。

Pathologic studies showed smooth muscle thick-ened around bronchia and lymphocyte infiltration under mu-cosa or around bronchia smooth muscle.

病理结果显示气道粘膜及小支气管平滑肌周围淋巴细胞、嗜酸性粒细胞及中性粒细胞浸润,气道平滑肌显著增生。

The cilium is prosperous, the mitochondrion is rich, and the endoplasmic reticulum and the Golgi complex are developed. There are a lot of secretory granule in goblet cell and mucous glandular cell, and there are many lymphocytic cells, neutrophilic granulocyte and a small quantity of eosinophilic granulocytes.

上皮纤毛发达,线粒体丰富,内质网、高尔基氏体发达,黏液性腺细胞和杯状细胞浆中有大量黏液分泌颗粒,基底膜下有大量淋巴细胞、中性粒细胞及少量嗜酸性粒细胞浸润。

Results: Subjects with severe asthma were more symptomatic,had a lower FEV1, and had more sputum neutrophilia (p = 0.007)and eosinophilia (p = 0.001). Exhaled nitric oxide was similarbetween groups.

本试验证明重度哮喘患者痰中中性粒细胞增多和嗜酸细胞增多更明显,且气道内细胞因子和趋化因子的表达也不同于中度哮喘。

Microscopically, edema、 small hemorrhagic spot on superficial mucosa, superficial epithelium was necrotic and scaled, foveola epithelial cells proliferated; lymphocytic and plasma cells infiltrated into the mesenchyme of lamina propria, sometimes neutrophil and eosinophilic granulocyte done.

镜下,粘膜浅层有水肿、出血点,表浅上皮坏死脱落,小凹上皮细胞增生;固有层间质中可见淋巴细胞和浆细胞浸润,有时可见少数中性粒细胞和嗜酸性粒细胞浸润。

MethodsRandomly clinical observation method was adopted,the treatment group(n=152)were treated with Kechuanning,and the control group(n=146)were treated with Guilongkechuanning capsule;The symptom score,the count of eosinophils,leukomonocyte and neutrophile granulocyte,and clinical therapeutic effect were observed.

方法采用随机临床对照观察方法,咳喘宁治疗152例为治疗组,以桂龙咳喘宁胶囊治疗146例为对照组,观察两组患者治疗前后症状评分,嗜酸粒细胞、淋巴细胞、中性粒细胞计数的变化,并比较两组的临床疗效。

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点;典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多;免疫组化提示CD68,髓过氧化物酶,中性粒细胞碱性磷酸酶积分明显减低,Ph染色体或BCR/ABL融合基因阳性,而幼年型CCML的Ph染色体常为阴性。

HSP is the most common blood vessel inflammation disease in childhood, its main clinical manifestations are nonthrombocyte reducing purpura, arthritis or arthralgia, bellyache, gastroenterostomy haemorrhage and nephritis, and its main pathological characteristics are general small blood vessel inflammation surrounded by neutrophils and eosinophils.

过敏性紫癜是儿童时期最常见的血管炎之一,以非血小板减少性紫癜、关节炎或关节痛、腹痛、胃肠道出血及肾炎为主要临床表现。主要病理变化为全身性小血管炎,小血管周围可见中性粒细胞及嗜酸性粒细胞浸润。

Machine still in a class of smaller phagocytes, which is the main neutrophil and eosinophil.

机体内还有一类较小的吞噬细胞,其中主要的是中性粒细胞和嗜酸性粒细胞。

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