喹唑啉

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

In this thesis, a series of benzamides and thioureas derivatives have been designed and prepared. By reasonable photoreaction conditions, a series of benzophenone and quinazoline compounds have been synthesized and structurally determined by NMR, MS and X-ray crystallography, respectively.

本文设计并合成了一系列苯甲酰胺和硫脲衍生物，通过选择合理的光反应条件，合成了一系列二苯甲酮和喹唑啉类化合物，应用核磁、质谱以及X-射线衍射技术对这些化合物的结构进行表征。

Odoquinazolin-4(3H)-one,7-methyl-4(3H)-quinazolinone,7-bromoquinazolin-4(3H)-one were synthesized by using anthranilic acid、2-amino-5-nitrobenzoic acid、2-amino-4-nitrobenzoic acid,6-nitro--4(3H)-quinazoline-one、o-amino-terephthalic acid, 2-amino-4-hydroxy benzoic acid、2-amino-5-bromo-benzoic acid、2-amino-5-iodine acid,1、4-butynediol、L-glutamine、isatin anhydride、formamide as starting materials and utilizing microwave-assisted synthetic approach.

本文利用微波辅助合成的方法，以邻氨基苯甲酸、2-氨基-5-硝基苯甲酸、2-氨基-4-硝基苯甲酸、邻氨基对苯二甲酸、2-氨基-4-羟基苯甲酸、2-氨基-5-溴苯甲酸、2-氨基-5-碘苯甲酸、5-甲基-2-氨基苯甲酸等为原料与甲酰胺反应，以及以1，4-丁炔二醇、L-谷氨酰胺与靛红酸酐反应，共合成了13个喹唑啉酮衍生。。。

Methods: In this paper, a quinazoline purine analogues for the parent nucleus, respectively, and four of its seven introduced to replace the structure of diverse and flexible side-chain amino-benzene, design a series of 4 - to replace the aniline-based -6 - methoxy --7 -(2 - hydroxy replace C oxy) quinazoline compounds.

目的：通过各种化学合成方法完成目标化合物4--6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉的合成并对目标化合物进行结构修饰，以期获得高活性的表皮生长因子受体酪氨酸激酶抑制剂。

METHODS: A simple and timesaving SOCl2 refluxed method was adopted to synthesize five quinazoline compounds as EGFR inhibitors.

我们改进了这种化合物的合成方法，用简单省时的SOCl2回流法合成五种喹唑啉类EGFR TK抑制剂。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况，详细介绍了新型喹唑啉类表皮生长因子受体抑制剂，着重研究了该类化合物的合成，设计并打通了合成路线，同时又合成了25个新化合物。

Objective: through various chemical synthesis target compounds 4 -- 6 - the - 7 -(2 - hydroxyl replace c oxygen radicals) quinazoline compounds were synthesized and the structure of the modified, so as to get high epidermal growth factor receptor tyrosine kinase inhibitor.

目的：通过各种化学合成方法完成目标化合物4--6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉的合成并对目标化合物进行结构修饰，以期获得高活性的表皮生长因子受体酪氨酸激酶抑制剂。

The N(1) atom of the quinazoline can form a stable H- bond with Met-769, while the N(3) atom can form a H-bond with a water molecule.

抑制剂喹唑啉环上的N(1)原子能够和Met-769上的 NH形成稳定的氢键，而抑制剂上的N(3)原子则和周围的一个水分子形成氢键。

In the course of the condensation of 2, 4, 6-triamino quinazoline with substituted benaldehyde, the solvent DMF was replaced by absolute ethanol and the dried 3A clathrates was used as the dehydrating agent in order to improve the yield.

在2，4，6-三氨基喹唑啉与取代苯甲醛的缩合过程中，用无水乙醇代替DMF作溶剂，并用干燥过的分子筛吸收反应过程中生成的水，从而简化了后处理的步骤，并提高了产率。

Subsequently, 3-(substituted-phenyl)isoxa- zole-5-methylamino-4(3H)-quinazoline derivatives 6a～6e were obtained by solid-grinding 5a～5e and 4 under the basic Al2O3 at room temperature.

4与5a～5e在碱性氧化铝作用下固相研磨合成了5种未见文献报道的新型的含异噁唑环的喹唑啉衍生物6a～6e。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。