唑

The key step involves reduction-amination of benzamine and -acetonide glycealdehyde 20 synthesized from cheap and available ascorbic acid . The hydrolysis product of 21 condensed with triphosgene to get 6, key intermediates of Linezolid and Eperizolid. After a series of reactions, we got Linezolid and Eperizolid in reasonable yields and purity. The spectrum and 〓 values of compounds 6 and other intermediates were identical with literature reported.

我们以国内非常便宜易得的维生素C为原料合成得到-丙酮保护的甘油醛20，20和取代苯胺经还原胺化反应制备得到二噁烷21，21水解后与三光气缩合成环得到利奈唑酮和埃皮唑酮的关键中间体6.6经一系列的反应合成得到了利奈唑酮和埃皮唑酮。6及一些中间体的〓D值与文献报道的数据相吻合。

We firstly introduced benzoazole (including benzimidazole, benzoxazole and benzothiazole) into the meso-positions of porphines and obtained five new porphyrins 36a-e. Their structures were characterized by 1H NMR, MS, UV-vis spectra and fluorescence emission spectra.

将苯并唑类基团(苯并咪唑、苯并噁唑和苯并噻唑)引入到卟吩中位，得到5个新型卟啉36a-e衍生物，并经核磁氢谱、质谱、紫外吸收光谱和荧光发射光谱表征了化合物的结构。

In this thesis, two series compounds of thiadiazole (2a~2f) and benzothiazole (5a~5f) were synthesized by using the reagent of iodobenzene diacetate. We also bound the iodobenzene diacetate reagent to the resin and applied it to synthesize thiadiazole and benzothiazole compounds.

本文利用二醋酸碘苯试剂分别与1-芳甲酰基-5-芳基-2-硫代缩二脲及1-芳甲酰基-3-芳基硫脲反应合成了噻二唑(2a~2f)和苯并噻唑(5a~5i)两个系列的杂环衍生物，并通过把二醋酸碘苯负载在高分子上合成了一类新型的固相氧化剂，同时考查了该固相氧化剂在噻二唑，苯并噻唑类化合物合成中的应用以及该固相氧化剂的循环使用。

Three kinds of small molecular copper and zinc superoxide dismutase mimics were synthesized with N, N-bis (benzimidazol-2-ylmethyl) amine (N3), N, N-bis (benzimidazol-2-ylmethyl) methylamine(MN3) and N,N-bis (benzimidazol-2-ylmethyl) benzylamine(BN3) as ligands. The com-plexes were characterized by UV, IR and element analysis and the structures were proposed.

模拟铜一锌超氧化物歧化酶的活性中心，以二(2-苯并咪唑)丙烷为桥、二(2-苯并咪唑亚甲基)胺(N3)、二(2-苯并咪唑亚甲基)甲胺(MN3)及二(2-苯并咪唑亚甲基)苄胺(BN3)为配体合成了3种异双核的小分子模型化合物，并进行了紫外、红外表征及元素分析，推测了可能的结构。

Materials and Methods: According to authoritative clinical diagnosis standards and evaluation standards, 90 cases of outpatients and inpatients were selected as the research subjects. These patients of H.pylori associated alimentary disease all failed on routine triple therapy and belonged to deficiency-cold of spleen and gaster, damp-heat of spleen and gaster as well as stagnant blood of gaster. 90 cases were divided into three groups stochastically. Among these patients, 30 cases were served as contrast groupⅠ treated by "Omeprazole, Clarithromycin, Metronidazole", 30 cases were served as contrast groupⅡtreated by "Omeprazole, Levofloxacin, Ornidazole", the other 30 cases were served as observation group treated by "Qingyou Soup" associated with above-mentioned routine medicines. The period of treatment of all three groups was 2 weeks.

资料与方法：根据2007年《第三次全国Hp共识会议》制定的Hp感染临床诊断标准、根除标准，以及2002年《中药新药临床研究指导原则》的病例选择标准、中医辨证标准、临床疗效判断标准，选择经西医常规三联疗法根除失败的Hp感染相关消化疾病，且中医辨证属脾胃虚寒、脾胃湿热、胃络瘀血证的门诊和住院患者90例，随机分为对照组Ⅰ、对照组Ⅱ、治疗组，对照组Ⅰ30例予常规三联药物&奥美拉唑、克拉霉素、甲硝唑&治疗，对照组Ⅱ30例予新三联药物&奥美拉唑、左氧氟沙星、奥硝唑&治疗，治疗组30例予中药方剂&清幽汤&联合上述常规三联药物治疗，三组均以1周为一个疗程，共治疗2个疗程。

The products have an isoxazole mother core with 3-morpholinopyridyl substitution and possess an approxi-mately planar structure. In addition a number of ester groups, amino groups, triazole groups and oxazolidi-none groups were introduced to 5-position of the isoxazole mother core.

这些化合物均以异噁唑为母核，具有近似的平面结构，在异噁唑环的3-位引入吗啉吡啶基，而在5-位引入酯基、取代氨基、三唑环和噁唑烷酮环。

Methods The clinical manifestations, mycological features, and the therapeutic results of 47 patients were retrospectively analyzed.

回顾分析47例真菌感染患者的临床表现、真菌学特征及治疗结果。17例患者单用氟康唑，21例单用伊曲康唑，9例氟康唑无效后改用伊曲康唑治疗。

Finally, the crystallization metastable zone of cefazolin sodium pentahydrate in water and the mixture of water and 2propanol at different temperatures was determined by the laser method. Valuable thermodynamics data for the industrial manufacture of cefazolin sodium pentahydrate were obtained.

本文测定了5～35℃范围内头孢唑林钠在不同配比的水乙醇、水丙酮、水异丙醇混合溶剂中的溶解度数据，采用热分析仪测定了头孢唑林钠的差热分析数据，推导了头孢唑林钠溶解度模型，为头孢唑林钠的结晶分离提供了热力学数据。

Finally,the crystallization metastable zone of cefazolin sodium pentahydrate in water and the mixture of water and 2propanol at different temperatures was determined by the laser method.Valuable thermodynamics data for the industrial manufacture of cefazolin sodium pentahydrate were obtained.KEY WORDS Cefazolin sodium pentahydrate;Crystallization;Thermodynamics;Metastable zone

本文测定了5~35℃范围内头孢唑林钠在不同配比的水乙醇、水丙酮、水异丙醇混合溶剂中的溶解度数据，采用热分析仪测定了头孢唑林钠的差热分析数据，推导了头孢唑林钠溶解度模型，为头孢唑林钠的结晶分离提供了热力学数据。

Valuable thermodynamics data for the industrial manufacture of cefazolin sodium pentahydrate were obtained.KEY WORDS Cefazolin sodium pentahydrate; Crystallization; Thermodynamics; Metastable zone

本文测定了5～35℃范围内头孢唑林钠在不同配比的水乙醇、水丙酮、水异丙醇混合溶剂中的溶解度数据，采用热分析仪测定了头孢唑林钠的差热分析数据，推导了头孢唑林钠溶解度模型，为头孢唑林钠的结晶分离提供了热力学数据。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。