唑

Methods The minimal inhibitory concentrations of 134 clincal isolates of bacteria were determined by standard agar dilution method,and miconazole nitrate cremor.

采用琼脂平皿稀释法测定2%硝酸舍他康唑软膏对134株临床分离分离致病菌的最低抑菌浓度，并与硝酸咪康唑霜进行比较。

Based on the problem of various types of catalyst and according to the features of carbonylation catalysts reactions, our team has been designed a series of new metal complexes of benimidazoles, which can be used for carbonylation catalyst of industry. Seven new benzimidazole derivatives were prepared by the o-phenylenediamine、oxalic acid、glycolic acid、monomethyl monopotassium malonate、ethyl cyanoacetate、succinic anhydride. The structures of them were confirmed by IR、Elemental analsis. The crystal structures of d and e were determined by X-ray single crystal diffraction of Germanic Bruker Smart APEX II CCD. The catalysis of them was tested by carbonylation reactions.

本文设计以邻苯二胺和草酸、羟基乙酸、丙二酸单甲酯、氰基乙酸乙酯、丁二酸单甲酯为原料采用PPA催化和无机酸催化法，合成了4种苯并咪唑-2-羧酸衍生物并进行了表征；培养了2个化合物d、e的晶体并测定和讨论了晶体结构；制备了3种未见报道的苯并咪唑金属配合物，对配合物在羰基化法制醋酐-醋酸反应的催化作用进行了初步试验。

METHODS 5-amino-1-hydroxyethyl pyrazole-4-carboylic acid was synthesized through condensation of ethyl cyanoacetate and triethyl orthoformate followed by one-pot methodology of cyclization,hydolysis.

方法原甲酸三乙酯与氰乙酸乙酯缩合，然后和羟乙基肼经环合、水解等一锅法合成5-氨基吡唑-4-甲酸，然后在亚硫酸钠存在条件下加热脱羧得到5-氨基-1-羟乙基吡唑。

Photoinduced Electron Transfer [2+2] Cycloaddition Reactions ofBenzannelated Isoquinolin-1-ones with Electron Deficient Alkenes Photoinduced [2+2] cycloaddition reactions of 11H-benzoxazolo[3,2-b]isoquinolin-11-one 8 and 11H-benzothiazolo[3,2-b]isoquinolin-11-one 13 with electron deficient alkenessuch as acrylonitrile, methyl acrylate, dimethyl fumarate and dimethyl maleate afforded a group of polycyclic isoquinoline derivatives bearing cyclobutane moieties ingood to excellent yields and resulted in the Schenck isomerization of the alkenes.

3苯并增环异喹啉-1-酮与缺电子烯烃的光诱导电子转移[2+2]环加成反应 11H-苯并恶唑[3，2-b]异喹啉-11-酮8和11H-苯并噻唑[3，2-b]异喹啉-11-酮13与缺电子烯烃如丙烯腈，丙烯酸甲酯，富马酸二甲酯及马来酸二甲酯的光诱导[2+2]环加成反应以高产率给出一系列含有环丁烷结构单元的多环异喹啉衍生物并导致烯烃的Schenck异构化作用。

This method is simple, rapid, accurate and effective for testing the impurity dibenzyl-(2-chlorophenyl) methanol in Clotrimazole and Betamethasone Dipropionate cream and for its content determination.

所建方法准确、简便、快速，适用于克霉唑倍他米松乳膏中克霉唑和二丙酸倍他米松的含量测定和杂质二苯基-（2-氯苯基）甲醇的含量测定。

Methods Glutaric dialdehyde was prepared from benzimidazolium salt and saturated dihalide by the addition-hydrolysis reaction of benzimidazolium salt with Di-Grignard reagent.

方法以苯并咪唑盐和二卤代烷为原料，利用苯并咪唑盐与双Grignard试剂的加成水解反应合成戊二醛。

Its main products include:ZOLEDRONIC ACID, ADAPALENE, SIMDAX, VORICONAZOLE, J ACID UREA, J ACID UREA SODIUM SALT, 1,7-CLEVE'S ACID, 1,6-CLEVE'S ACID, 1,5- DINAPHTHYL ISOCYANATE, 5- INROINDOLE,----2-METHOXYIMINO-2-（FURYL-2-YL）ACETIC ACID AMMONIUM SALTand etc.

部分产品远销美国、德国、英国、印度、日本等十几个国家和地区，主要产品有：唑来磷酸、阿达帕林、左西孟旦、伏立康唑、猩红酸、猩红酸钠盐、双介酸、1，7克力夫酸1，6克力夫酸、1，5-萘二异氰酸酯、5-硝基吲哚、甲氧亚胺基呋喃乙酸铵等。

Disubstituted 2-isoxazolines were oxidized to corresponding isoxazoles by NO in dichloromethane.

3、3，5-二取代的-2-异恶唑啉在NO作用下可以发生芳环化反应，生成对应的2-异恶唑化合物。

Disubstituted 2-isoxazolines were oxidized to corresponding isoxazoles by NO in dichloromethane.

所以反应的反应过程是受溶剂控制的。3、3，5-二取代的-2-异恶唑啉在NO作用下可以发生芳环化反应，生成对应的2-异恶唑化合物。

A bis-imdazoline corrosion inhibitor JUC was synthesized by reacting with divinyl three amine,and its quaternary ammonium JUCI was also synthesized for corrosion inhibition in acids.

以己二酸、二乙烯三胺为原料合成了双环咪唑啉缓蚀剂JUC，并对其季铵化后得到了适于酸化用的双环咪唑啉季铵盐缓蚀剂JUCI；采用静态挂片失重法对合成的缓蚀剂在酸化条件下的缓蚀性能及与非离子表面活性剂SA-1复配后的缓蚀性能进行了评价研究。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。